Platelet aggregation inhibiting toxin

Toxin which inhibits agonist-induced platelet aggregation, the self-adhesion of platelets via adhesion molecules.

See also UniProtKB-keyword


Numerous snake venom families are able to inhibit platelet aggregation by enzymatic and non-enzymatic mechanisms. Enzymatic protein families include metalloproteinases, phospholipases A2, nucleotide pyrophosphatases/phosphodiesterases, 5'-nucleotidases and L-amino-acid oxidases, while non-enzymatic protein families include Snaclecs, disintegrins and snake three-finger toxins. One protein of the natriuretic peptide family has also been described to inhibit platelet aggregation.

Figure 1: Different platelet receptors and their ligands. These molecules are the targets of venom proteins that inhibit platelet aggregation (see text for more details).

Platelet aggregation inhibiting toxins act by binding to platelet receptors, as well as to their ligands. Until now, three ligands and four platelet receptors have been described to be inhibited by venom proteins:

- von Willebrand Factor (vWF) is a large glycoprotein that is released from endothelial cells in blood plasma as well as from platelets. Under high shear stress conditions, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-V-IX. It also acts as a chaperone for coagulation factor VIII (F8), delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma (Swieringa et al., 2014 ).

- Thrombin is the main effector of the coagulation cascade that induces fibrin clot formation, as well as a strong platelet agonist. It activates platelets by cleaving the protease-activated receptors (PAR) (Mackman, 2008 ).

- ADP activates platelets by binding to G-protein coupled receptors P2Y1 and P2Y12
- Integrin αIIbβ3 (ITGA2B/ITGB3) is the most abundantly expressed receptor on platelets. On resting platelets this integrin assumes a bent form with low ligand affinity. When platelets are activated, it shows high affinity for fibrinogen, vWF, fibronectin, and vitronectin (Swieringa et al., 2014 ).

- GPIb (GP1BA) is a component of the GPIb-V-IX complex. This complex binds vWF (A1 domain), allowing platelet adhesion and platelet plug formation at sites of vascular injury. GPIb is composed of two disulfide-linked GPIbβ subunits that are non covalently linked to one GPIbα subunit.

- Integrin α2/β1 (ITGA2/ITGB1) is a receptor for collagen, and its function depends on conformational changes. Its activation depends on cytoskeleton-mediated kindlin-3 and talin-1 interactions. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression (Nieswandt et al., 2009, Swieringa et al., 2014 ).

- Platelet glycoprotein VI (GPVI or GP6) is the principal signaling receptor for collagen on platelets. It is a member of the immunoglobulin superfamily, which associates with the ITAM-bearing FcRγ-chain. GPVI is only expressed on platelets and megakaryocytes. Stimulation via GPVI leads to full platelet activation, including integrin activation, secretion and procoagulant activity (Swieringa et al., 2014 ).



The table below shows the different platelet receptors and receptor activators, as well as the families of venom proteins that impair them.

Platelet receptor activators Families of venom proteins

von Willebrand Factor (vWF)

metalloproteinase
Thrombin

Snaclec
ADP

5'-nucleotidase
nucleotide pyrophosphatase/phosphodiesterase
Platelet receptors Families of venom proteins
αIIb/β3 (ITGA2B/ITGB3) disintegrin and disintegrin domains of metalloproteinase
three-finger toxin
GPIb (GP1BA)

metalloproteinase
Snaclec
α2/β1 (ITGA2/ITGB1) disintegrin
metalloproteinase
Snaclec

GPVI (GP6)

metalloproteinase

Venom protein entries in UniProtKB/Swiss-Prot

306 entries grouped by species (browse by taxonomy, browse by keywords)

2 entries

Acanthophis antarcticus (Common death adder)

Select_allDeselect_all
PA2B1_ACAAN Basic phospholipase A2 acanthin-1 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...
PA2B2_ACAAN Basic phospholipase A2 acanthin-2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...

1 entry

Agkistrodon bilineatus (Cantil) (Tropical moccasin)

PA2B2_AGKBI Basic phospholipase A2 2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

3 entries

Agkistrodon contortrix contortrix (Southern copperhead)

Select_allDeselect_all "Agkistrodon contortrix contortrix" VenomZone page
DIDA_AGKCO Disintegrin acostatin-alpha [Cleaved into: Disintegrin ... Disintegrin family, Dimeric ...
VM2AB_AGKCO Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2CO_AGKCO Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...

1 entry

Agkistrodon contortrix laticinctus (Broad-banded copperhead) (Agkistrodon mokasen laticinctus)

VM3AD_AGKCL Zinc metalloproteinase-disintegrin-like ACLD (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

1 entry

Agkistrodon piscivorus leucostoma (Western cottonmouth) (Acontias leucostoma)

VM2V2_AGKPL Zinc metalloproteinase/disintegrin VMP-II (AplVMP2) [Cleaved ... Venom metalloproteinase (M12B) ...

3 entries

Agkistrodon piscivorus piscivorus (Eastern cottonmouth)

Select_allDeselect_all "Agkistrodon piscivorus piscivorus" VenomZone page
DIDA_AGKPI Disintegrin piscivostatin-alpha (PVS-alpha) Disintegrin family, Dimeric ...
VM2PB_AGKPI Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2_AGKPI Disintegrin applaggin (Applagin) (Platelet aggregation ... Venom metalloproteinase (M12B) ...

1 entry

Anuroctonus phaiodactylus (Mafia scorpion)

PA2_ANUPH Phospholipase A2 phaiodactylipin (PLA2) [Cleaved into: ... Phospholipase A2 family

22 entries

Austrelaps superbus (Lowland copperhead snake) (Hoplocephalus superbus)

Select_allDeselect_all
PA2A1_AUSSU Acidic phospholipase A2 S1-11 (svPLA2) (EC 3.1.1.4) (ASPLA1) ... Phospholipase A2 family, Group I ...
PA2A4_AUSSU Acidic phospholipase A2 S7-48J (svPLA2) (EC 3.1.1.4) (ASPLA4) ... Phospholipase A2 family, Group I ...
PA2A5_AUSSU Acidic phospholipase A2 S9-53F (svPLA2) (EC 3.1.1.4) (ASPLA5) ... Phospholipase A2 family, Group I ...
PA2A6_AUSSU Acidic phospholipase A2 S3-24 (svPLA2) (EC 3.1.1.4) (ASPLA6) ... Phospholipase A2 family, Group I ...
PA2A7_AUSSU Acidic phospholipase A2 S15-109 (svPLA2) (EC 3.1.1.4) (ASPLA7) ... Phospholipase A2 family, Group I ...
PA2AA_AUSSU Acidic phospholipase A2 S5-32M (svPLA2) (EC 3.1.1.4) (ASPLA10) ... Phospholipase A2 family, Group I ...
PA2AB_AUSSU Acidic phospholipase A2 S13-69J (svPLA2) (EC 3.1.1.4) (ASPLA11) ... Phospholipase A2 family, Group I ...
PA2AC_AUSSU Acidic phospholipase A2 S4-30 (svPLA2) (EC 3.1.1.4) (ASPLA12) ... Phospholipase A2 family, Group I ...
PA2AD_AUSSU Acidic phospholipase A2 S14-72F (svPLA2) (EC 3.1.1.4) (ASPLA13) ... Phospholipase A2 family, Group I ...
PA2AE_AUSSU Acidic phospholipase A2 S8-51 (svPLA2) (EC 3.1.1.4) (ASPLA14) ... Phospholipase A2 family, Group I ...
PA2AF_AUSSU Acidic phospholipase A2 S12-65J (svPLA2) (EC 3.1.1.4) (ASPLA15) ... Phospholipase A2 family, Group I ...
PA2AG_AUSSU Acidic phospholipase A2 S16-19 (svPLA2) (EC 3.1.1.4) (ASPLA16) ... Phospholipase A2 family, Group I ...
PA2AH_AUSSU Acidic phospholipase A2 S17-58 (svPLA2) (EC 3.1.1.4) (ASPLA17) ... Phospholipase A2 family, Group I ...
PA2B2_AUSSU Basic phospholipase A2 S6-45 (svPLA2) (EC 3.1.1.4) (ASPLA2) ... Phospholipase A2 family, Group I ...
PA2B8_AUSSU Basic phospholipase A2 S10-58F (svPLA2) (EC 3.1.1.4) (ASPLA8) ... Phospholipase A2 family, Group I ...
PA2B9_AUSSU Basic phospholipase A2 S11-61 (svPLA2) (EC 3.1.1.4) (ASPLA9) ... Phospholipase A2 family, Group I ...
PA2B_AUSSU Basic phospholipase A2 S2-22 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...
PA2SA_AUSSU Phospholipase A2 superbin a (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...
PA2SB_AUSSU Phospholipase A2 superbin b (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...
PA2SC_AUSSU Phospholipase A2 superbin c (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...
PA2SD_AUSSU Phospholipase A2 superbin d (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...
PA2_AUSSU Phospholipase A2 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine ... Phospholipase A2 family, Group I ...

3 entries

Bitis arietans (African puff adder)

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VM2D2_BITAR Disintegrin isoform D-2 Venom metalloproteinase (M12B) ...
VM2D3_BITAR Disintegrin isoform D-3 Venom metalloproteinase (M12B) ...
VM2_BITAR Disintegrin bitistatin (Arietin) (Bitan) (Disintegrin isoform ... Venom metalloproteinase (M12B) ...

2 entries

Bitis rhinoceros (West African gaboon viper) (Vipera rhinoceros)

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SLRA_BITRH Snaclec rhinocetin subunit alpha (C-type lectin like protein 1) Snaclec family
SLRB_BITRH Snaclec rhinocetin subunit beta (C-type lectin like protein 2) Snaclec family

1 entry

Bothriechis lateralis (Side-striped palm pitviper)

VM2H1_BOTLA Zinc metalloproteinase-disintegrin BlatH1 (EC 3.4.24.-) (Snake ... Venom metalloproteinase (M12B) ...

3 entries

Bothrops alternatus (Urutu) (Rhinocerophis alternatus)

Select_allDeselect_all
SLAB_BOTAL Snaclec bothroalternin subunit alpha/beta (Bothrojaracin-like ... Snaclec family
VM2_BOTAL Disintegrin DisBa-01 Venom metalloproteinase (M12B) ...
VM3BG_BOTAL Zinc metalloproteinase-disintegrin-like BaG (EC 3.4.24.-) (Snake ... Venom metalloproteinase (M12B) ...

1 entry

Bothrops asper (Terciopelo)

"Bothrops asper" VenomZone page
VM2_BOTAS Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...

2 entries

Bothrops atrox (Barba amarilla) (Fer-de-lance)

Select_allDeselect_all
VM11_BOTAT Snake venom metalloproteinase atroxlysin-1 (SVMP) (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM2_BOTAT Disintegrin batroxostatin (Disintegrin colombistatin) (Platelet ... Venom metalloproteinase (M12B) ...

1 entry

Bothrops cotiara (Cotiara) (Rhinocerophis cotiara)

VM2_BOTCO Disintegrin cotiarin (Platelet aggregation activation inhibitor) Venom metalloproteinase (M12B) ...

1 entry

Bothrops diporus (Chaco lancehead) (Bothrops neuwiedi diporus)

SL1_BOTDP Snaclec (Fragments) Snaclec family

2 entries

Bothrops erythromelas (Caatinga lance head)

Select_allDeselect_all
PA2A_BOTER Acidic phospholipase A2 BE-I-PLA2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
VM3BE_BOTER Zinc metalloproteinase-disintegrin-like berythractivase (EC ... Venom metalloproteinase (M12B) ...

1 entry

Bothrops fonsecai (Fonseca's lancehead) (Rhinocerophis fonsecai)

VM2_BOTFO Disintegrin (Platelet aggregation activation inhibitor) ... Venom metalloproteinase (M12B) ...

3 entries

Bothrops insularis (Golden lancehead) (Lachesis insularis)

Select_allDeselect_all
SLA_BOTIN Snaclec bothroinsularin subunit alpha (BIN) Snaclec family
SLB_BOTIN Snaclec bothroinsularin subunit beta (BIN) Snaclec family
VM2IA_BOTIN Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...

16 entries

Bothrops jararaca (Jararaca) (Bothrops jajaraca)

Select_allDeselect_all
PA2A_BOTJA Acidic phospholipase A2 (svPLA2) (EC 3.1.1.4) (BJ-PLA2) ... Phospholipase A2 family, Group ...
SL1A_BOTJA Snaclec GPIB-binding protein subunit alpha (GPIb-BP subunit ... Snaclec family
SL1B_BOTJA Snaclec GPIB-binding protein subunit beta (GPIb-BP subunit beta) Snaclec family
SLAA_BOTJA Snaclec bothrojaracin subunit alpha (BJC subunit alpha) Snaclec family
SLAB_BOTJA Snaclec bothrojaracin subunit beta (BJC subunit beta) Snaclec family
VM2J2_BOTJA Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2JA_BOTJA Disintegrin jarastatin (JT) (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...
VM2JC_BOTJA Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2JR_BOTJA Zinc metalloproteinase-disintegrin jararin (EC 3.4.24.-) (Snake ... Venom metalloproteinase (M12B) ...
VM3B1_BOTJA Zinc metalloproteinase-disintegrin-like bothrojarin-1 (EC ... Venom metalloproteinase (M12B) ...
VM3B2_BOTJA Zinc metalloproteinase-disintegrin-like bothrojarin-2 (EC ... Venom metalloproteinase (M12B) ...
VM3B3_BOTJA Zinc metalloproteinase-disintegrin-like bothrojarin-3 (EC ... Venom metalloproteinase (M12B) ...
VM3B4_BOTJA Zinc metalloproteinase-disintegrin-like bothrojarin-4 (EC ... Venom metalloproteinase (M12B) ...
VM3BP_BOTJA Zinc metalloproteinase-disintegrin-like bothropasin (EC ... Venom metalloproteinase (M12B) ...
VM3H3_BOTJA Zinc metalloproteinase-disintegrin-like HF3 (EC 3.4.24.-) (Snake ... Venom metalloproteinase (M12B) ...
VM3JA_BOTJA Zinc metalloproteinase-disintegrin-like jararhagin (EC ... Venom metalloproteinase (M12B) ...

3 entries

Bothrops jararacussu (Jararacussu)

Select_allDeselect_all "Bothrops jararacussu" VenomZone page
PA2A_BOTJR Acidic phospholipase A2 BthA-1 (svPLA2) (EC 3.1.1.4) (BOJU-III) ... Phospholipase A2 family, Group ...
VM1B2_BOTJR Snake venom metalloproteinase BjussuMP-2 (SVMP) (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM3B1_BOTJR Zinc metalloproteinase-disintegrin-like BjussuMP-1 (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

4 entries

Bothrops leucurus (Whitetail lancehead)

Select_allDeselect_all
OXLA_BOTLC L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) (Fragment) Flavin monoamine oxidase family, ...
VM1LA_BOTLC Snake venom metalloproteinase leucurolysin-A (Leuc-A) (SVMP) (EC ... Venom metalloproteinase (M12B) ...
VM3LB_BOTLC Zinc metalloproteinase leucurolysin-B (Leuc-B) (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM3L_BOTLC Zinc metalloproteinase-disintegrin-like leucurogin (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

1 entry

Bothrops moojeni (Lance-headed viper) (Caissaca)

PA2A_BOTMO Acidic phospholipase A2 BmooPLA2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

1 entry

Bothrops pauloensis (Neuwied's lancehead) (Bothrops neuwiedi pauloensis)

PA2A1_BOTPA Acidic phospholipase A2 (Bp-PLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

1 entry

Bothrops pirajai (Piraja's lance0 head)

"Bothrops pirajai" VenomZone page
PA2A1_BOTPI Acidic phospholipase A2 BpirPLA2-I (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

1 entry

Bungarus fasciatus (Banded krait) (Pseudoboa fasciata)

VM3_BUNFA Zinc metalloproteinase-disintegrin-like BfMP (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

4 entries

Bungarus multicinctus (Many-banded krait)

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3NO52_BUNMU Long neurotoxin homolog NTL2 Snake three-finger toxin family, ...
3NO56_BUNMU Long neurotoxin homolog TA-bm16 (Delta-protein) Snake three-finger toxin family, ...
3NO5I_BUNMU Gamma-bungarotoxin (Long neurotoxin homolog NTL2I) Snake three-finger toxin family, ...
VM3_BUNMU Zinc metalloproteinase-disintegrin-like BmMP (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

11 entries

Calloselasma rhodostoma (Malayan pit viper) (Agkistrodon rhodostoma)

Select_allDeselect_all
OXLA_CALRH L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) Flavin monoamine oxidase family, ...
PA2AA_CALRH Acidic phospholipase A2 S1E6-a (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AB_CALRH Acidic phospholipase A2 S1E6-b (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AC_CALRH Acidic phospholipase A2 S1E6-c (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AE_CALRH Acidic phospholipase A2 H1E6 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
SLEA_CALRH Snaclec rhodocetin subunit alpha Snaclec family
SLEB_CALRH Snaclec rhodocetin subunit beta Snaclec family
SLEC_CALRH Snaclec rhodocetin subunit gamma (Fragment) Snaclec family
SLED_CALRH Snaclec rhodocetin subunit delta Snaclec family
VM1K_CALRH Snake venom metalloproteinase kistomin (SVMP) (EC 3.4.24.-) Venom metalloproteinase (M12B) ...
VM2RH_CALRH Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...

2 entries

Cerastes cerastes (Horned desert viper)

Select_allDeselect_all
PA2A1_CERCE Acidic phospholipase A2 CC-PLA2-1 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2A2_CERCE Acidic phospholipase A2 CC-PLA2-2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

2 entries

Cerastes vipera (Sahara sand viper)

Select_allDeselect_all
DIDA_CERVI Disintegrin CV-11-alpha (CV11) Disintegrin family, Dimeric ...
DIDB_CERVI Disintegrin CV-11-beta (CV11-beta) (Fragment) Disintegrin family, Dimeric ...

1 entry

Cerrophidion sasai (Costa Rica montane pitviper)

VM2_CERSA Disintegrin sasaimin Venom metalloproteinase (M12B) ...

4 entries

Crotalus adamanteus (Eastern diamondback rattlesnake)

Select_allDeselect_all "Crotalus adamanteus" VenomZone page
PDE1_CROAD Venom phosphodiesterase 1 (Ectonucleotide ... Nucleotide ...
PDE2_CROAD Venom phosphodiesterase 2 (Ectonucleotide ... Nucleotide ...
VM28_CROAD Zinc metalloproteinase-disintegrin 8 (EC 3.4.24.-) (Snake venom ... Venom metalloproteinase (M12B) ...
VM2_CROAD Zinc metalloproteinase-disintegrin VMP-II (CamVMP-II) (EC ... Venom metalloproteinase (M12B) ...

7 entries

Crotalus atrox (Western diamondback rattlesnake)

Select_allDeselect_all
VM1CR_CROAT Snake venom metalloproteinase crotalin (SVMP) (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM2AE_CROAT Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2IA_CROAT Disintegrin atroxatin (Fragment) Venom metalloproteinase (M12B) ...
VM2IC_CROAT Disintegrin crotatroxin (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...
VM2V2_CROAT Zinc metalloproteinase-disintegrin VMP-II (CaVMP-II) (EC ... Venom metalloproteinase (M12B) ...
VM3AA_CROAT Zinc metalloproteinase-disintegrin-like atrolysin-A (EC ... Venom metalloproteinase (M12B) ...
VM3VB_CROAT Zinc metalloproteinase-disintegrin-like VAP2B (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

1 entry

Crotalus basiliscus (Mexican west-coast rattlesnake)

VM2I_CROBA Disintegrin basilicin (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...

1 entry

Crotalus cerastes cerastes (Mojave desert sidewinder)

VM2I_CROCC Disintegrin cerastin (Platelet aggregation activation inhibitor) Venom metalloproteinase (M12B) ...

1 entry

Crotalus cerberus (Arizona black rattlesnake) (Crotalus oreganus cerberus)

VM2I_CROCE Disintegrin cereberin (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...

1 entry

Crotalus durissus durissus (Central American rattlesnake)

VM2I_CRODD Disintegrin durissin (Platelet aggregation activation inhibitor) Venom metalloproteinase (M12B) ...

1 entry

Crotalus durissus terrificus (South American rattlesnake)

OXLA_CRODU L-amino acid oxidase (LAAO) (LAO) (EC 1.4.3.2) (Bordonein-L) ... Flavin monoamine oxidase family, ...

6 entries

Crotalus horridus (Timber rattlesnake)

Select_allDeselect_all
PA2A6_CROHD Acidic phospholipase A2 CH-E6' (svPLA2) (EC 3.1.1.4) (CH-E6) ... Phospholipase A2 family, Group ...
PA2AA_CROHD Acidic phospholipase CHA-E6a (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AB_CROHD Acidic phospholipase A2 CHA-E6b (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
SLA_CROHD Snaclec CHH-B subunit alpha Snaclec family
SLB_CROHD Snaclec CHH-B subunit beta Snaclec family
VM212_CROHD Disintegrin horrdistatin-2 [Cleaved into: Disintegrin ... Venom metalloproteinase (M12B) ...

1 entry

Crotalus molossus molossus (Northern black-tailed rattlesnake)

VM2I_CROMM Disintegrin molossin (Platelet aggregation activation inhibitor) Venom metalloproteinase (M12B) ...

1 entry

Crotalus oreganus abyssus (Grand Canyon rattlesnake) (Crotalus abyssus)

PA2AD_CROOA Acidic phospholipase A2 CoaPLA2 (svPLA2) (EC 3.1.1.4) (Cvv-E6d) ... Phospholipase A2 family, Group ...

1 entry

Crotalus oreganus lutosus (Great basin rattlesnake) (Crotalus viridis lutosus)

VM2I_CROOL Disintegrin lutosin (Platelet aggregation activation inhibitor) Venom metalloproteinase (M12B) ...

1 entry

Crotalus ruber ruber (Red diamond rattlesnake)

VM2_CRORU Disintegrin rubistatin (Fragment) Venom metalloproteinase (M12B) ...

1 entry

Crotalus scutulatus scutulatus (Mojave rattlesnake)

VM212_CROSS Disintegrin mojastin-2 [Cleaved into: Disintegrin mojastin-1] Venom metalloproteinase (M12B) ...

1 entry

Crotalus simus (Central American rattlesnake) (Caudisona simus)

VM2_CROSM Disintegrin simusmin Venom metalloproteinase (M12B) ...

1 entry

Crotalus tzabcan (Yucatan neotropical rattlesnake) (Crotalus simus tzabcan)

VM2_CROTA Disintegrin tzabcanin Venom metalloproteinase (M12B) ...

11 entries

Crotalus viridis viridis (Prairie rattlesnake)

Select_allDeselect_all
PA2AA_CROVV Acidic phospholipase A2 Cvv-E6a (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AB_CROVV Acidic phospholipase A2 Cvv-E6b (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AC_CROVV Acidic phospholipase A2 Cvv-E6c (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AE_CROVV Acidic phospholipase A2 Cvv-E6e (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AF_CROVV Acidic phospholipase A2 Cvv-E6f (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AG_CROVV Acidic phospholipase A2 Cvv-E6g (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AH_CROVV Acidic phospholipase A2 Cvv-E6h (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
VM2IV_CROVV Disintegrin viridistatin (Fragment) Venom metalloproteinase (M12B) ...
VM2I_CROVV Disintegrin viridin (Platelet aggregation activation inhibitor) Venom metalloproteinase (M12B) ...
VM2V2_CROVV Zinc metalloproteinase/disintegrin VMP-II [Cleaved into: Snake ... Venom metalloproteinase (M12B) ...
VM3CR_CROVV Zinc metalloproteinase-disintegrin-like crovidisin (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

1 entry

Daboia palaestinae (Palestine viper) (Vipera palaestinae)

SLB_DABPA Snaclec VP12 subunit B Snaclec family

1 entry

Daboia russelii (Russel's viper) (Vipera russelii)

OXLA_DABRR L-amino-acid oxidase (DrLAO) (LAAO) (EC 1.4.3.2) Flavin monoamine oxidase family, ...

2 entries

Daboia siamensis (Eastern Russel's viper) (Daboia russelii siamensis)

Select_allDeselect_all
OXLA_DABSI L-amino-acid oxidase (DRS-LAAO) (LAAO) (LAO) (EC 1.4.3.2) ... Flavin monoamine oxidase family, ...
SLA_DABSI Snaclec dabocetin subunit alpha (C-type lectin-like 8) Snaclec family

13 entries

Deinagkistrodon acutus (Hundred-pace snake) (Agkistrodon acutus)

Select_allDeselect_all
PA2A_DEIAC Acidic phospholipase A2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
SLAA_DEIAC Snaclec anticoagulant protein subunit A (AaACP-A) Snaclec family
SLAB_DEIAC Snaclec anticoagulant protein subunit B (AaACP-B) (ACF 1/2 ... Snaclec family
SLCA_DEIAC Snaclec agkicetin-C subunit alpha (Antithrombin A subunit A) Snaclec family
SLCB_DEIAC Snaclec agkicetin-C subunit beta (Antithrombin A subunit B) Snaclec family
SLUA_DEIAC Snaclec agkisacutacin subunit A (Agk-A) Snaclec family
SLUB_DEIAC Snaclec agkisacutacin subunit B (Agk-B) Snaclec family
VM2A2_DEIAC Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2M2_DEIAC Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2_DEIAC Disintegrin accutin Venom metalloproteinase (M12B) ...
VM3AH_DEIAC Zinc metalloproteinase-disintegrin-like acurhagin (Acur) (EC ... Venom metalloproteinase (M12B) ...
VM3AK_DEIAC Zinc metalloproteinase-disintegrin-like agkihagin (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VMP3A_DEIAC Zinc metalloproteinase-disintegrin-like AAV1 (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

1 entry

Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps)

3SPT_DENAN Thrombostatin (Glycoprotein IIb-IIIa antagonist) (Platelet ... Snake three-finger toxin family, ...

2 entries

Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)

Select_allDeselect_all
3SP1_DENJA Toxin S5C1 Snake three-finger toxin family, ...
3SPM_DENJA Dendroaspin (Glycoprotein IIb-IIIa antagonist) (Mambin) ... Snake three-finger toxin family, ...

2 entries

Drysdalia coronoides (White-lipped snake) (Hoplocephalus coronoides)

Select_allDeselect_all
PA214_DRYCN Phospholipase A2 147 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine ... Phospholipase A2 family, Group I ...
PA222_DRYCN Phospholipase A2 PS22 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine ... Phospholipase A2 family, Group I ...

6 entries

Echis carinatus (Saw-scaled viper)

Select_allDeselect_all
DIDLA_ECHCA Disintegrin schistatin-like subunit A Disintegrin family, Dimeric ...
DIDLB_ECHCA Disintegrin schistatin-like subunit B Disintegrin family, Dimeric ...
DIDS_ECHCA Disintegrin schistatin Disintegrin family, Dimeric ...
PA2A1_ECHCA Acidic phospholipase A2 EC-I (EC-I-PLA2) (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
SLA_ECHCA Snaclec echicetin subunit alpha (Fragment) Snaclec family
SLB_ECHCA Snaclec echicetin subunit beta Snaclec family

2 entries

Echis carinatus sochureki (Saw-scaled viper)

Select_allDeselect_all
SLB_ECHCS Snaclec echicetin subunit beta Snaclec family
VM2EA_ECHCS Disintegrin echistatin-alpha (Carinatin) (Platelet aggregation ... Venom metalloproteinase (M12B) ...

2 entries

Echis leucogaster (Roman's saw-scaled viper) (Echis carinatus leucogaster)

Select_allDeselect_all
VM2LA_ECHLE Disintegrin leucogastin-A Venom metalloproteinase (M12B) ...
VM2LB_ECHLE Disintegrin leucogastin-B Venom metalloproteinase (M12B) ...

4 entries

Echis multisquamatus (Central Asian sand viper)

Select_allDeselect_all
DIDBA_ECHML Disintegrin EMS11A Disintegrin family, Dimeric ...
SLA_ECHML Snaclec EMS16 subunit alpha (EMS16A) Snaclec family
SLB_ECHML Snaclec EMS16 subunit beta (EMS16B) Snaclec family
VM2MU_ECHML Disintegrin multisquamatin Venom metalloproteinase (M12B) ...

8 entries

Echis ocellatus (Ocellated saw-scaled viper)

Select_allDeselect_all "Echis ocellatus" VenomZone page
DID1_ECHOC Disintegrin Eo1 subunit 1 (Eo1-1) Disintegrin family, Dimeric ...
DID4A_ECHOC Disintegrin EO4A (Dim-3 SP6) (Eo-10) (Eo-10c1) Disintegrin family, Dimeric ...
DID5A_ECHOC Disintegrin EO5A (Eo-12) Disintegrin family, Dimeric ...
DID5B_ECHOC Disintegrin EO5B (EO4B) Disintegrin family, Dimeric ...
DIS_ECHOC Disintegrin ocellatusin (Short ocellatusion precursor Eo10c-10) Disintegrin family, Short ...
VM2OC_ECHOC Zinc metalloproteinase/disintegrin (Long ocellatusin precursor ... Venom metalloproteinase (M12B) ...
VM2OI_ECHOC Disintegrin ocellatin Venom metalloproteinase (M12B) ...
VM3E2_ECHOC Zinc metalloproteinase-disintegrin-like EoVMP2 (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

4 entries

Echis pyramidum leakeyi (Leakey's carpet viper) (Echis carinatus leakeyi)

Select_allDeselect_all
VM2EB_ECHPL Disintegrin echistatin-beta Venom metalloproteinase (M12B) ...
VM2EG_ECHPL Disintegrin echistatin-gamma Venom metalloproteinase (M12B) ...
VM2PA_ECHPL Disintegrin pyramidin-A Venom metalloproteinase (M12B) ...
VM2PB_ECHPL Disintegrin pyramidin-B Venom metalloproteinase (M12B) ...

4 entries

Eristicophis macmahoni (Leaf-nosed viper)

Select_allDeselect_all
DIDAA_ERIMA Disintegrin EMF10A (EMF-10A) (Eristocophin I) (Platelet ... Disintegrin family, Dimeric ...
VM2AB_ERIMA Disintegrin EMF10B (EMF-10B) (Eristocophin II) (Platelet ... Venom metalloproteinase (M12B) ...
VM2TI_ERIMA Disintegrin eristicophin (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...
VM2TO_ERIMA Disintegrin eristostatin Venom metalloproteinase (M12B) ...

2 entries

Gloydius blomhoffii (Mamushi) (Agkistrodon halys blomhoffi)

Select_allDeselect_all
OXLA_GLOBL L-amino-acid oxidase (LAAO) (LAO) (M-LAO) (EC 1.4.3.2) Flavin monoamine oxidase family, ...
VM2_GLOBL Disintegrin halysin (Platelet aggregation activation inhibitor) Venom metalloproteinase (M12B) ...

8 entries

Gloydius brevicaudus (Korean slamosa snake) (Agkistrodon halys brevicaudus)

Select_allDeselect_all
VM2HS_GLOBR Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2L4_GLOBR Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2MB_GLOBR Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2MD_GLOBR Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2S2_GLOBR Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2S3_GLOBR Zinc metalloproteinase-disintegrin salmosin-3 (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM3S4_GLOBR Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM3S5_GLOBR Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...

8 entries

Gloydius halys (Chinese water mocassin) (Agkistrodon halys)

Select_allDeselect_all
PA2A_GLOHA Acidic phospholipase A2 (svPLA2) (EC 3.1.1.4) (APLA2) ... Phospholipase A2 family, Group ...
VM2AG_GLOHA Zinc metalloproteinase-disintegrin agkistin (EC 3.4.24.-) (Snake ... Venom metalloproteinase (M12B) ...
VM2DI_GLOHA Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2H1_GLOHA Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2H2_GLOHA Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2_GLOHA Disintegrin saxatilin Venom metalloproteinase (M12B) ...
VM3HA_GLOHA Zinc metalloproteinase-disintegrin-like halysase (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM3H_GLOHA Disintegrin-like halysetin Venom metalloproteinase (M12B) ...

4 entries

Gloydius ussuriensis (Ussuri mamushi) (Gloydius blomhoffii ussuriensis)

Select_allDeselect_all
PA2A_GLOUS Acidic phospholipase A2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
VM2I1_GLOUS Disintegrin ussuristatin-1 (US-1) Venom metalloproteinase (M12B) ...
VM2I2_GLOUS Disintegrin ussuristatin-2 (US-2) Venom metalloproteinase (M12B) ...
VM2US_GLOUS Zinc metalloproteinase/disintegrin ussurin [Cleaved into: Snake ... Venom metalloproteinase (M12B) ...

1 entry

Hippasa partita (Funnel-web spider) (Hippasa deserticola)

VMPAR_HIPPR Zinc metalloproteinase partitagin (EC 3.4.24.-) (Fragment) Venom metalloproteinase (M12B) ...

3 entries

Lachesis muta muta (Bushmaster)

Select_allDeselect_all
PA22_LACMU Phospholipase A2 2 (svPLA2) (EC 3.1.1.4) (LM-PLA2-II) ... Phospholipase A2 family, Group ...
PA2A1_LACMU Acidic phospholipase A2 1 (svPLA2) (EC 3.1.1.4) (LM-PLA2-I) ... Phospholipase A2 family, Group ...
VM2I_LACMU Disintegrin lachesin (Platelet aggregation activation inhibitor) Venom metalloproteinase (M12B) ...

12 entries

Macrovipera lebetina (Levantine viper) (Vipera lebetina)

Select_allDeselect_all
DID1A_MACLB Disintegrin lebein-1-alpha (ML-3) (MS-II) (Platelet aggregation ... Disintegrin family, Dimeric ...
DID1B_MACLB Disintegrin lebein-1-beta (MS-II) (Platelet aggregation ... Disintegrin family, Dimeric ...
DID2A_MACLB Disintegrin lebein-2-alpha (ML-(2,8,15)) (MS-I) (VLDA) (ml-G2) Disintegrin family, Dimeric ...
LEB_MACLB Lebetin-2-alpha (L2alpha) [Cleaved into: Lebetin-1-alpha ... Natriuretic peptide family
OXLA_MACLB L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) (Fragments) Flavin monoamine oxidase family, ...
PA2A1_MACLB Acidic phospholipase A2 1 (Vl-PLA2-1) (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2A2_MACLB Acidic phospholipase A2 2 (Vl-PLA2-2) (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
SLA_MACLB Snaclec lebecetin subunit alpha (Fragment) Snaclec family
SLB_MACLB Snaclec lebecetin subunit beta (Fragment) Snaclec family
VM1F_MACLB Snake venom metalloproteinase fibrolase (SVMP) (EC 3.4.24.72) ... Venom metalloproteinase (M12B) ...
VM1L4_MACLB Snake venom metalloproteinase lebetase-4 (Le-4) (Le4) (EC ... Venom metalloproteinase (M12B) ...
VM2L2_MACLB Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...

3 entries

Macrovipera lebetina obtusa (Levant blunt-nosed viper) (Vipera lebetina obtusa)

Select_allDeselect_all
DID4_MACLO Disintegrin VLO4 Disintegrin family, Dimeric ...
DID5B_MACLO Disintegrin VLO5B Disintegrin family, Dimeric ...
VM25A_MACLO Disintegrin VLO5A Venom metalloproteinase (M12B) ...

1 entry

Macrovipera lebetina transmediterranea (Blunt-nosed viper) (Vipera lebetina transmediterranea)

VM3LC_MACLN Disintegrin-like leberagin-C Venom metalloproteinase (M12B) ...

2 entries

Naja atra (Chinese cobra)

Select_allDeselect_all "Naja atra" VenomZone page
VM3A_NAJAT Zinc metalloproteinase-disintegrin-like atrase-A (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM3_NAJAT Zinc metalloproteinase-disintegrin-like NaMP (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

2 entries

Naja kaouthia (Monocled cobra) (Naja siamensis)

Select_allDeselect_all
OXLA_NAJKA L-amino-acid oxidase (K-LAO) (LAAO) (LAO) (EC 1.4.3.2) ... Flavin monoamine oxidase family, ...
VM3K_NAJKA Hemorrhagic metalloproteinase-disintegrin-like kaouthiagin (EC ... Venom metalloproteinase (M12B) ...

1 entry

Naja mossambica (Mozambique spitting cobra)

"Naja mossambica" VenomZone page
VM3M1_NAJMO Snake venom metalloproteinase-disintegrin-like mocarhagin (MOC) ... Venom metalloproteinase (M12B) ...

1 entry

Naja oxiana (Central Asian cobra) (Oxus cobra)

OXLA_NAJOX L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) (Fragments) Flavin monoamine oxidase family, ...

3 entries

Ophiophagus hannah (King cobra) (Naja hannah)

Select_allDeselect_all
OXLA_OPHHA L-amino-acid oxidase (LAAO) (LAO) (Oh-LAAO) (EC 1.4.3.2) Flavin monoamine oxidase family, ...
PA2A1_OPHHA Acidic phospholipase A2 1 (svPLA2) (EC 3.1.1.4) (APLA2-1) (OHV ... Phospholipase A2 family, Group I ...
VM3_OPHHA Zinc metalloproteinase-disintegrin-like ohanin (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

1 entry

Ovophis monticola (Chinese mountain pitviper) (Trimeresurus monticola)

PA2A_OVOMO Acidic phospholipase A2 Omo-E6 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

1 entry

Ovophis okinavensis (Ryukyu Island pit viper) (Trimeresurus okinavensis)

PA2A1_OVOOK Acidic phospholipase A2 DE-I (svPA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

1 entry

Philodryas patagoniensis (Ringless green snake)

VMXP_PHIPA Snake venom metalloproteinase patagonfibrase (SVMP) (EC ... Venom metalloproteinase (M12B) ...

1 entry

Porthidium nasutum (Hognosed pitviper) (Bothrops nasutus)

PA2A_PORNA Acidic phospholipase A2 PnPLA2 (svPLA2) (EC 3.1.1.4) (Fragment) Phospholipase A2 family, Group ...

2 entries

Protobothrops elegans (Elegant pitviper) (Trimeresurus elegans)

Select_allDeselect_all
VM2E1_PROEL Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2E2_PROEL Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...

9 entries

Protobothrops flavoviridis (Habu) (Trimeresurus flavoviridis)

Select_allDeselect_all
SLAA_PROFL Snaclec flavocetin-A subunit alpha (FL-A subunit alpha) Snaclec family
SLAB_PROFL Snaclec flavocetin-A subunit beta (FL-A subunit beta) Snaclec family
VM2C_PROFL Disintegrin CTF-II (Cytotoxic factor 2) [Cleaved into: ... Venom metalloproteinase (M12B) ...
VM2FL_PROFL Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2HA_PROFL Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2T_PROFL Disintegrin triflavin (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...
VM3HA_PROFL Zinc metalloproteinase/disintegrin-like HR1a (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM3HB_PROFL Zinc metalloproteinase-disintegrin-like HR1b (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VSP1_PROFL Thrombin-like enzyme flavoxobin (SVTLE) (EC 3.4.21.74) ... Peptidase S1 family, Snake venom ...

7 entries

Protobothrops jerdonii (Jerdon's pitviper) (Trimeresurus jerdonii)

Select_allDeselect_all
PA2A_PROJR Acidic phospholipase A2 jerdoxin (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
SLA_PROJR Snaclec jerdonibitin subunit alpha (TJ-GPIb-bp subunit alpha) Snaclec family
SLB_PROJR Snaclec jerdonibitin subunit beta (TJ-GPIb-bp subunit beta) Snaclec family
VM2JN_PROJR Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2JT_PROJR Zinc metalloproteinase-disintegrin jerdonitin (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM2J_PROJR Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM3_PROJR Zinc metalloproteinase-disintegrin-like jerdohagin (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

4 entries

Protobothrops mucrosquamatus (Taiwan habu) (Trimeresurus mucrosquamatus)

Select_allDeselect_all
PA2A2_PROMU Acidic phospholipase A2 2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
VM2P1_PROMU Zinc metalloproteinase/disintegrin PMMP-1 [Cleaved into: Snake ... Venom metalloproteinase (M12B) ...
VM2P2_PROMU Zinc metalloproteinase/disintegrin PMMP-2 [Cleaved into: Snake ... Venom metalloproteinase (M12B) ...
VM2T3_PROMU Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...

2 entries

Protobothrops tokarensis (Tokara habu) (Trimeresurus tokarensis)

Select_allDeselect_all
SLA_PROTO Snaclec tokaracetin subunit alpha (Fragment) Snaclec family
SLB_PROTO Snaclec tokaracetin subunit beta (Fragment) Snaclec family

1 entry

Pseudechis papuanus (Papuan black snake)

PA2_PSEPP Phospholipase A2 (svPLA2) (EC 3.1.1.4) (Phosphatidylcholine ... Phospholipase A2 family, Group I ...

1 entry

Sistrurus miliarius barbouri (Dusky pigmy rattlesnake) (Sistrurus barbouri)

VM2I_SISMB Disintegrin barbourin (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...

1 entry

Sistrurus tergeminus (Western massasauga) (Sistrurus catenatus tergeminus)

VM2I_SISTE Disintegrin tergeminin (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...

2 entries

Trimeresurus albolabris (White-lipped pit viper) (Cryptelytrops albolabris)

Select_allDeselect_all
VM2AL_TRIAB Zinc metalloproteinase homolog-disintegrin albolatin Venom metalloproteinase (M12B) ...
VM2G_TRIAB Disintegrin albolabrin (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...

2 entries

Trimeresurus borneensis (Borneo pit viper)

Select_allDeselect_all
PA2A_TRIBO Acidic phospholipase A2 Tbo-E6 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2B_TRIBO Basic phospholipase A2 Tbo-G6D49 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

1 entry

Trimeresurus gracilis (Kikuchi habu)

PA2A_TRIGS Acidic phospholipase A2 Tgc-E6 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

4 entries

Trimeresurus gramineus (Bamboo pit viper) (Indian green tree viper)

Select_allDeselect_all
VM2B_TRIGA Disintegrin trigramin-beta-2 (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...
VM2G_TRIGA Disintegrin trigramin-gamma (Platelet aggregation activation ... Venom metalloproteinase (M12B) ...
VM2TA_TRIGA Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM3G1_TRIGA Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...

4 entries

Trimeresurus puniceus (Flat-nosed pitviper)

Select_allDeselect_all
PA2AA_TRIPE Acidic phospholipase A2 Tpu-E6a (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AB_TRIPE Acidic phospholipase A2 Tpu-E6b (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AC_TRIPE Acidic phospholipase A2 Tpu-E6c (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2B_TRIPE Basic phospholipase A2 Tpu-G6D49 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

9 entries

Trimeresurus stejnegeri (Chinese green tree viper) (Viridovipera stejnegeri)

Select_allDeselect_all
PA2A5_TRIST Acidic phospholipase A2 5 (svPLA2) (EC 3.1.1.4) (PLA2-V) ... Phospholipase A2 family, Group ...
PA2AA_TRIST Acidic phospholipase A2 Ts-A1 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AC_TRIST Acidic phospholipase A2 Ts-A3 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AF_TRIST Acidic phospholipase A2 Ts-A6 (svPLA2) (EC 3.1.1.4) (CTs-A6) ... Phospholipase A2 family, Group ...
PA2AG_TRIST Acidic phospholipase A2 CTs-A1 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AH_TRIST Acidic phospholipase A2 CTs-A2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2AI_TRIST Acidic phospholipase A2 CTs-A3 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
VM2_TRIST Zinc metalloproteinase-disintegrin stejnitin (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM3SA_TRIST Zinc metalloproteinase-disintegrin-like stejnihagin-A (EC ... Venom metalloproteinase (M12B) ...

1 entry

Vipera ammodytes ammodytes (Western sand viper)

VM2A6_VIPAA Disintegrin VA6 Venom metalloproteinase (M12B) ...

1 entry

Vipera ammodytes meridionalis (Eastern sand viper)

PA2B_VIPAE Basic phospholipase A2 vipoxin B chain (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...

3 entries

Vipera berus berus (Common viper)

Select_allDeselect_all
DID7A_VIPBB Disintegrin VB7A Disintegrin family, Dimeric ...
OXLA_VIPBB L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) (Fragments) Flavin monoamine oxidase family, ...
VM27B_VIPBB Disintegrin VB7B Venom metalloproteinase (M12B) ...

3 entries

Vipera nikolskii (Nikolsky's adder)

Select_allDeselect_all
PA2B1_VIPNI Basic phospholipase A2 chain HDP-1P (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2B2_VIPNI Basic phospholipase A2 chain HDP-2P (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2H_VIPNI Acidic phospholipase A2 inhibitor chain HPD-1I (svPLA2 homolog) ... Phospholipase A2 family, Group ...

1 entry

Vipera renardi (Steppe viper) (Vipera ursinii renardi)

PA2A2_VIPRE Acidic phospholipase A2 Vur-PL2B (Vur-PL2) (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...