Cardiotoxin

Cardiotoxins are components that are specifically toxic to the heart. They cause heart electrophysiology dysfunction or/and muscle damage.

Also see UniProtKB-keyword

Venom protein entries in UniProtKB/Swiss-Prot

134 entries grouped by species (browse by taxonomy, browse by keywords)

4 entries

Anthopleura elegantissima (Green aggregating anemone) (Actinia elegantissima)

Select_allDeselect_all
NA11_ANTEL Delta-actitoxin-Ael1b (Delta-AITX-Ael1b) (Toxin APE 1-1) Sea anemone sodium channel ...
NA122_ANTEL Delta-actitoxin-Ael1d (Delta-AITX-Ael1d) (Toxin APE 2-2) Sea anemone sodium channel ...
NA13_ANTEL Delta-actitoxin-Ael1c (Delta-AITX-Ael1c) (Toxin APE 1-2) Sea anemone sodium channel ...
NA1C_ANTEL Delta-actitoxin-Ael1a (Delta-AITX-Ael1a) (APE 2-1) ... Sea anemone sodium channel ...

2 entries

Anthopleura fuscoviridis (Sea anemone)

Select_allDeselect_all
NA11_ANTFU Delta-actitoxin-Afv1a (Delta-AITX-Afv1a) (Toxin AFT-I) (AFI) Sea anemone sodium channel ...
NA12_ANTFU Delta-actitoxin-Afv1b (Delta-AITX-Afv1b) (AFT-II) (AFII) Sea anemone sodium channel ...

4 entries

Anthopleura sp. (strain 'Zhanjiang') (Sea anemone)

Select_allDeselect_all
NA116_ANTS7 Delta-actitoxin-Aspp1d (Delta-AITX-Aspp1d) (Toxin Hk16a) Sea anemone sodium channel ...
NA12A_ANTS7 Delta-actitoxin-Aspp1a (Delta-AITX-Aspp1a) (Toxin Hk2a) Sea anemone sodium channel ...
NA17A_ANTS7 Delta-actitoxin-Aspp1b (Delta-AITX-Aspp1b) (Toxin Hk7a) Sea anemone sodium channel ...
NA18A_ANTS7 Delta-actitoxin-Aspp1c (Delta-AITX-Aspp1c) (Toxin Hk8a) Sea anemone sodium channel ...

6 entries

Anthopleura xanthogrammica (Giant green sea anemone) (Actinia xanthogrammica)

Select_allDeselect_all
NA12_ANTXA Delta-actitoxin-Axm1e (Delta-AITX-Axm1e) (PCR2-5) (Toxin PCR2) Sea anemone sodium channel ...
NA13_ANTXA Delta-actitoxin-Axm1d (Delta-AITX-Axm1d) (PCR2-1) (Toxin PCR3) Sea anemone sodium channel ...
NA14_ANTXA Delta-actitoxin-Axm1f (Delta-AITX-Axm1f) (PCR2-10) (Toxin PCR4) Sea anemone sodium channel ...
NA16_ANTXA Delta-actitoxin-Axm1h (Delta-AITX-Axm1h) (PCR3-7) (Toxin PCR6) Sea anemone sodium channel ...
NA1A_ANTXA Delta-actitoxin-Axm1a (Delta-AITX-Axm1a) (Anthopleurin-A) (AP-A) ... Sea anemone sodium channel ...
NA1B_ANTXA Delta-actitoxin-Axm1b (Delta-AITX-Axm1b) (Anthopleurin-B) (AP-B) ... Sea anemone sodium channel ...

1 entry

Atractaspis bibronii (Bibron's mole viper) (Southern stiletto snake)

SRTXB_ATRBI Bibrotoxin (BTX) Endothelin/sarafotoxin family

2 entries

Atractaspis engaddensis (Israeli burrowing asp) (Israeli mole viper)

Select_allDeselect_all
SRTXD_ATREN Sarafotoxin-D (SRTX-D) (S6D) Endothelin/sarafotoxin family
SRTX_ATREN Sarafotoxin [Cleaved into: Sarafotoxin-A, Ser-isoform (SRTX-A) ... Endothelin/sarafotoxin family

2 entries

Atractaspis irregularis (Variable burrowing asp) (Elaps irregularis)

Select_allDeselect_all
SRTX1_ATRIR Sarafotoxin-i1 (SRTX-i1) (Sarafotoxin-i3) (SRTX-i3) Endothelin/sarafotoxin family
SRTX2_ATRIR Sarafotoxin-i2 (SRTX-i2) Endothelin/sarafotoxin family

1 entry

Atractaspis microlepidota microlepidota

SRTXL_ATRMM Long-sarafotoxin (L-SRTX) [Cleaved into: Sarafotoxin-m (SRTX-m); ... Endothelin/sarafotoxin family

2 entries

Bunodosoma granuliferum (Red warty sea anemone)

Select_allDeselect_all
NA12_BUNGR Delta-actitoxin-Bgr2a (Delta-AITX-Bgr2a) (Bg II) (BgII) ... Sea anemone sodium channel ...
NA13_BUNGR Delta-actitoxin-Bgr2b (Delta-AITX-Bgr2b) (Bg III) (BgIII) ... Sea anemone sodium channel ...

1 entry

Conus villepinii (Villepin's cone)

CCAP_CONVL ConoCAP [Cleaved into: ConoCAP-a (CCAP-vil); ConoCAP-b; ... Not in a family

1 entry

Daboia russelii (Russel's viper) (Vipera russelii)

3SA1_DABRR Cytotoxin drCT-1 (drCT-I) (Fragment) Snake three-finger toxin family, ...

2 entries

Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps)

Select_allDeselect_all
3SL2_DENAN Toxin C10S2C2 Snake three-finger toxin family, ...
VKTHC_DENAN Kunitz-type serine protease inhibitor homolog calcicludine (CAC) ... Venom Kunitz-type family

1 entry

Dendroaspis jamesoni kaimosae (Eastern Jameson's mamba)

3SL8_DENJA Toxin S4C8 Snake three-finger toxin family, ...

2 entries

Dendroaspis polylepis polylepis (Black mamba)

Select_allDeselect_all
3SL2_DENPO Toxin FS-2 (FS2) Snake three-finger toxin family, ...
3SLS_DENPO Calciseptin (Calciseptine) (CaS) (L-type calcium channel ... Snake three-finger toxin family, ...

5 entries

Hemachatus haemachatus (Rinkhals) (Sepedon haemachatus)

Select_allDeselect_all
3SB1_HEMHA Cytotoxin 1 (Hemolytic protein 12B) Snake three-finger toxin family, ...
3SB2_HEMHA Cytotoxin 2 (Toxin 12A) Snake three-finger toxin family, ...
3SB3_HEMHA Cytotoxin 3 (Toxin 11/11A) Snake three-finger toxin family, ...
3SBH_HEMHA Three-finger hemachatoxin Snake three-finger toxin family, ...
3SOE_HEMHA Cytotoxin homolog (Toxin 9B/9BB) Snake three-finger toxin family, ...

1 entry

Heterometrus bengalensis (Indian black scorpion)

BENG_HETBN Bengalin (Fragment) Not in a family

1 entry

Leiurus quinquestriatus hebraeus (Yellow scorpion)

SCB1_LEIQH Beta-mammal/insect toxin Lqhb1 (Lqh-beta-1) Long (4 C-C) scorpion toxin ...

10 entries

Naja annulifera (Banded Egyptian cobra) (Naja haje annulifera)

Select_allDeselect_all
3SA1_NAJHA Cytotoxin 1 (Toxin V(II)1) Snake three-finger toxin family, ...
3SA2_NAJHA Cytotoxin 2 (Toxin V(II)2/V(II)2A) Snake three-finger toxin family, ...
3SA3_NAJHA Cytotoxin 3 (Toxin CM-8/CM-8A) Snake three-finger toxin family, ...
3SA4_NAJHA Cytotoxin 4 (Toxin CM-11) Snake three-finger toxin family, ...
3SA5_NAJHA Cytotoxin 5 (Toxin CM-6) Snake three-finger toxin family, ...
3SA6_NAJHA Cytotoxin 6 (Toxin CM-2H) Snake three-finger toxin family, ...
3SA7_NAJHA Cytotoxin 7 (Toxin CM-4B) Snake three-finger toxin family, ...
3SA8_NAJHA Cytotoxin 8 (Toxin CM-7) Snake three-finger toxin family, ...
3SA9_NAJHA Cytotoxin 9 (Toxin CM-2e) Snake three-finger toxin family, ...
3SAA_NAJHA Cytotoxin 10 (Toxin CM-4a) Snake three-finger toxin family, ...

28 entries

Naja atra (Chinese cobra)

Select_allDeselect_all "Naja atra" VenomZone page
3SA1A_NAJAT Cytotoxin 1a (Cardiotoxin-1a) Snake three-finger toxin family, ...
3SA1B_NAJAT Cytotoxin 1b (Cardiotoxin-1b) Snake three-finger toxin family, ...
3SA1C_NAJAT Cytotoxin 1c (Cardiotoxin-1c) Snake three-finger toxin family, ...
3SA1D_NAJAT Cytotoxin 1d/1e (Cardiotoxin-1d/1e) Snake three-finger toxin family, ...
3SA1F_NAJAT Cytotoxin 1f (Cardiotoxin 1f) (Fragment) Snake three-finger toxin family, ...
3SA1_NAJAT Cytotoxin 1 (CX1) (Cardiotoxin 1) (CTX-1) (CTX1) (Cardiotoxin ... Snake three-finger toxin family, ...
3SA2_NAJAT Cytotoxin 2 (Cardiotoxin 1A) (Cardiotoxin 2) (CTX-2) ... Snake three-finger toxin family, ...
3SA3A_NAJAT Cytotoxin 3a (Cardiotoxin-31) (Ctx-31) (Cardiotoxin-3a) Snake three-finger toxin family, ...
3SA3B_NAJAT Cytotoxin 3b (Cardiotoxin 3b) Snake three-finger toxin family, ...
3SA3D_NAJAT Cytotoxin 3d (Cardiotoxin 3d) Snake three-finger toxin family, ...
3SA3_NAJAT Cytotoxin 3 (Cardiotoxin 3) (CTX-3) (CTX3) (Cardiotoxin A3) (CTX ... Snake three-finger toxin family, ...
3SA4N_NAJAT Cytotoxin 4N (Cardiotoxin-4N) (CTX-4N) Snake three-finger toxin family, ...
3SA4_NAJAT Cytotoxin 4 (CTX-4M) (CTX4) (Cardiotoxin A4) (CTX A4) ... Snake three-finger toxin family, ...
3SA5_NAJAT Cytotoxin 5 (Cardiotoxin 5) (CTX5) Snake three-finger toxin family, ...
3SA6_NAJAT Cytotoxin 6 (Cardiotoxin-6) (CTX6) Snake three-finger toxin family, ...
3SA8A_NAJAT Cytotoxin 8 (Cardiotoxin-8) (CTX8) Snake three-finger toxin family, ...
3SA8B_NAJAT Cytotoxin 8 (Cardiotoxin VIII) (Cardiotoxin-8) (CTX8) Snake three-finger toxin family, ...
3SAA_NAJAT Cytotoxin 10 (Cardiotoxin-10) (CTX10) (Ctx-10) Snake three-finger toxin family, ...
3SADB_NAJAT Cytotoxin SP13b Snake three-finger toxin family, ...
3SAFA_NAJAT Cytotoxin SP15a Snake three-finger toxin family, ...
3SAFC_NAJAT Cytotoxin SP15c Snake three-finger toxin family, ...
3SAFD_NAJAT Cytotoxin SP15d Snake three-finger toxin family, ...
3SAG_NAJAT Cytotoxin najalgesin (Fragment) Snake three-finger toxin family, ...
3SAN_NAJAT Cytotoxin 6 (Cardiotoxin 6) (CTX6) (Cardiotoxin A6) (CTX A6) ... Snake three-finger toxin family, ...
3SAPF_NAJAT Cytotoxin I-like P-15 (Cardiotoxin I-like P-15) Snake three-finger toxin family, ...
3SATF_NAJAT Cytotoxin I-like T-15 (Cardiotoxin I-like T-15) Snake three-finger toxin family, ...
3SAT_NAJAT Cytotoxin 5 (Cardiotoxin A4b) (CTX-A4b) (Cardiotoxin T) ... Snake three-finger toxin family, ...
3SOF7_NAJAT Cytotoxin 7 (Cardiotoxin-7) (CTX7) (Ctx-7) (Cardiotoxin-like ... Snake three-finger toxin family, ...

1 entry

Naja haje haje (Egyptian cobra)

3SA5_NAJHH Cytotoxin 5 (Toxin CM-8) Snake three-finger toxin family, ...

8 entries

Naja kaouthia (Monocled cobra) (Naja siamensis)

Select_allDeselect_all
3NO2_NAJKA Tryptophan-containing weak neurotoxin (WTX) Snake three-finger toxin family, ...
3SA1_NAJKA Cytotoxin 1 (NK-CT1) Snake three-finger toxin family, ...
3SA2_NAJKA Cytotoxin 2 Snake three-finger toxin family, ...
3SA3_NAJKA Cytotoxin 3 (CX3) (Toxin CM-7) Snake three-finger toxin family, ...
3SA4_NAJKA Cytotoxin 4 (Cytotoxin IV) Snake three-finger toxin family, ...
3SA5_NAJKA Cytotoxin 5 (Cytotoxin II) Snake three-finger toxin family, ...
3SA7A_NAJKA Cytotoxin 2 (CX2) (Toxin CM-7A) Snake three-finger toxin family, ...
3SA8_NAJKA Cytotoxin 1 (CTX1) (CX1) (Cardiotoxin F8) (Toxin CM-6) Snake three-finger toxin family, ...

1 entry

Naja melanoleuca (Forest cobra) (Black-lipped cobra)

3SA1_NAJME Cytotoxin 1 (Cytotoxin V(II)1) Snake three-finger toxin family, ...

5 entries

Naja mossambica (Mozambique spitting cobra)

Select_allDeselect_all "Naja mossambica" VenomZone page
3SA1_NAJMO Cytotoxin 1 (CTX M1) (Cardiotoxin IIB) (CTX-IIB) (Cytotoxin ... Snake three-finger toxin family, ...
3SA2_NAJMO Cytotoxin 2 (CTX M2) (Cardiotoxin IIA) (CTX IIA) (Cytotoxin ... Snake three-finger toxin family, ...
3SA3_NAJMO Cytotoxin 3 (CTX M4) (Cytotoxin V(II)3) Snake three-finger toxin family, ...
3SA4_NAJMO Cytotoxin 4 (CTX M3) (Cardiotoxin V(II)4) Snake three-finger toxin family, ...
3SA5_NAJMO Cytotoxin 5 (CTX M5) (CTX V) Snake three-finger toxin family, ...

10 entries

Naja naja (Indian cobra)

Select_allDeselect_all
3SA1_NAJNA Cytotoxin 1 (Cobramine-A) (Cytotoxin I) (Cytotoxin XI) ... Snake three-finger toxin family, ...
3SA2A_NAJNA Cytotoxin 2a (CTX2a) (Cytotoxin 2) (CTX2) Snake three-finger toxin family, ...
3SA2_NAJNA Cytotoxin 2 (Cobramine-B) (Cytotoxin II) Snake three-finger toxin family, ...
3SA3A_NAJNA Cytotoxin 3a (CTX3a) (Fragment) Snake three-finger toxin family, ...
3SA3_NAJNA Cytotoxin 3 (Cytotoxin IIa) Snake three-finger toxin family, ...
3SA7_NAJNA Cytotoxin 7 (CTX7) Snake three-finger toxin family, ...
3SA8_NAJNA Cytotoxin 8 (CTX8) Snake three-finger toxin family, ...
3SA9_NAJNA Cytotoxin 9 (CTX9) (Fragment) Snake three-finger toxin family, ...
3SAA_NAJNA Cytotoxin 10 (CTX10) Snake three-finger toxin family, ...
3SAW_NAJNA Cytotoxin NN-32 (Fragment) Snake three-finger toxin family, ...

3 entries

Naja nivea (Cape cobra) (Coluber niveus)

Select_allDeselect_all
3SA1_NAJNI Cytotoxin 1 (Toxin V(II)1) Snake three-finger toxin family, ...
3SA2_NAJNI Cytotoxin 2 (Toxin V(II)2) Snake three-finger toxin family, ...
3SA3_NAJNI Cytotoxin 3 (Toxin V(II)3) Snake three-finger toxin family, ...

3 entries

Naja oxiana (Central Asian cobra) (Oxus cobra)

Select_allDeselect_all
3SA1_NAJOX Cytotoxin 1 (Cytotoxin I) (CTI) Snake three-finger toxin family, ...
3SA2_NAJOX Cytotoxin 2 (Cytotoxin II) (CTII) Snake three-finger toxin family, ...
3SA5_NAJOX Cytotoxin Vc-5 Snake three-finger toxin family, ...

1 entry

Naja pallida (Red spitting cobra)

3SA1_NAJPA Cytotoxin 1 (CTX-1) (Cardiotoxin gamma) Snake three-finger toxin family, ...

1 entry

Naja sagittifera (Andaman cobra)

3SAS_NAJSG Cytotoxin sagitoxin (Cardiotoxin sagitoxin) Snake three-finger toxin family, ...

13 entries

Naja sputatrix (Malayan spitting cobra) (Naja naja sputatrix)

Select_allDeselect_all
3SA0_NAJSP Cytotoxin (CTX) (Cardiotoxin) Snake three-finger toxin family, ...
3SA1_NAJSP Cytotoxin 1 (Cardiotoxin-1) (CTX-1) (Ctx1) Snake three-finger toxin family, ...
3SA2A_NAJSP Cytotoxin 2a (Cardiotoxin 2a) (CTX-2a) (Ctx2a) Snake three-finger toxin family, ...
3SA2B_NAJSP Cytotoxin 2b (Cardiotoxin-2b) (CTX-2b) (Ctx2b) Snake three-finger toxin family, ...
3SA2C_NAJSP Cytotoxin 2c (Cardiotoxin-2c) (CTX-2c) (Ctx2c) Snake three-finger toxin family, ...
3SA3_NAJSP Cytotoxin 3 (Cardiotoxin-3) (CTX-3) (Ctx3) Snake three-finger toxin family, ...
3SA4A_NAJSP Cytotoxin 4a (Cardiotoxin-4a) (CTX-4a) (Ctx4a) Snake three-finger toxin family, ...
3SA4B_NAJSP Cytotoxin 4b (Cardiotoxin-4b) (CTX-4b) (Ctx4b) Snake three-finger toxin family, ...
3SA5A_NAJSP Cytotoxin 5a (Cardiotoxin 5a) (CTX-5a) (Ctx5a) Snake three-finger toxin family, ...
3SA5B_NAJSP Cytotoxin 5b (Cardiotoxin 5b) (CTX-5b) (Ctx5b) Snake three-finger toxin family, ...
3SA6_NAJSP Cytotoxin 6 (Cardiotoxin-6) (CTX-6) (Ctx6) (Fragment) Snake three-finger toxin family, ...
3SA7_NAJSP Cytotoxin 7 (Cardiotoxin-7) (CTX-7) (Ctx7) (Fragment) Snake three-finger toxin family, ...
3SAC3_NAJSP Cytotoxin KJC3 Snake three-finger toxin family, ...

7 entries

Ophiophagus hannah (King cobra) (Naja hannah)

Select_allDeselect_all
3SDC1_OPHHA Beta-cardiotoxin CTX21 Snake three-finger toxin family, ...
3SDC3_OPHHA Beta-cardiotoxin CTX23 Snake three-finger toxin family, ...
3SDC4_OPHHA Beta-cardiotoxin CTX14 Snake three-finger toxin family, ...
3SDC5_OPHHA Beta-cardiotoxin CTX15 (OH-84) Snake three-finger toxin family, ...
3SDC7_OPHHA Beta-cardiotoxin CTX27 (OH-27) Snake three-finger toxin family, ...
3SDC9_OPHHA Beta-cardiotoxin CTX9 Snake three-finger toxin family, ...
PA2A1_OPHHA Acidic phospholipase A2 1 (svPLA2) (EC 3.1.1.4) (APLA2-1) (OHV ... Phospholipase A2 family, Group I ...

2 entries

Parabuthus granulatus (Granulated thick-tailed scorpion)

Select_allDeselect_all
KURT1_PARGR Alpha-toxin PgKL1 (Kurtoxin-like 1) (Kurtoxin-like I) (KLI) Long (4 C-C) scorpion toxin ...
KURT2_PARGR Toxin PgKL2 (Kurtoxin-like 2) (Kurtoxin-like II) (KLII) Long (4 C-C) scorpion toxin ...

3 entries

Phlogius sp. (Tarantula spider)

Select_allDeselect_all
HM1A_PHLSP Mu-theraphotoxin-Phlo1a (Mu-TRTX-Phlo1a) Huwentoxin-1 family
HM1B_PHLSP Mu-theraphotoxin-Phlo1b (Mu-TRTX-Phlo1b) Huwentoxin-1 family
HM2A_PHLSP Mu-theraphotoxin-Phlo2a (Mu-TRTX-Phlo2a) (Fragment) Phrixotoxin family