Bothrops atrox (barba amarilla)

Venom composition
Figure 1: Composition of B.atrox venom, studied at both proteomic (A) (Kohlhoffa, et al., 2012 ) and transcriptomic levels (B) (Neiva et al., 2009 ). Disintegrins have been detected by proteomic analysis but not by transcriptomic analysis, suggesting that they are encoded by the SVMP family. VEGF (PDGF/VEGF growth factor ), PA2 inhibitor and BPP precursor (bradykinin-potentiating peptide ) have only been detected by transcriptomic analysis, whereas all other families have been detected by both proteomic and transcriptomic analysis. CRISP, PA2 (phospholipase A2 ), serine protease, C-type lectin (true venom lectin ), LAAO (L-amino-acid oxidase also known as flavin monoamine oxidase ), SVMP (snake venom metalloproteinase ).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website
and the WHO venomous snake database to access snake distribution and antivenom products.
Lethal dose LD(50) is 5.89 mg/kg by intraperitoneal injection into mice
(117.8 (103.7-137.3) ug/mice) (Kohlhoff et al., 2012 ).

Venom protein entries in UniProtKB/Swiss-Prot

13 entries grouped by species (browse by taxonomy, browse by keywords)

13 entries

Bothrops atrox (Barba amarilla) (Fer-de-lance)

Select_allDeselect_all
BPP12_BOTAT Bradykinin-potentiating peptide 12a (BPP-12a) ... Bradykinin-potentiating peptide ...
CAMP_BOTAT Cathelicidin-related peptide batroxicidin (Cathelicidin-related ... Cathelicidin family
LECG_BOTAT C-type lectin galatrox (CTL) (Fragments) True venom lectin family
OXLA_BOTAT L-amino-acid oxidase (BatroxLAAO) (LAAO) (LAO) (EC 1.4.3.2) ... Flavin monoamine oxidase family, ...
PA2H1_BOTAT Phospholipase A2 homolog 1 (svPLA2 homolog) (Myotoxin I) Phospholipase A2 family, Group ...
VM11_BOTAT Snake venom metalloproteinase atroxlysin-1 (SVMP) (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM1B1_BOTAT Snake venom metalloproteinase Batx-1 (SVMP) (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM2_BOTAT Disintegrin batroxostatin (Disintegrin colombistatin) (Platelet ... Venom metalloproteinase (M12B) ...
VM31_BOTAT Zinc metalloproteinase-disintegrin-like batroxstatin-1 (EC ... Venom metalloproteinase (M12B) ...
VM32_BOTAT Zinc metalloproteinase-disintegrin-like batroxstatin-2 (EC ... Venom metalloproteinase (M12B) ...
VM33_BOTAT Zinc metalloproteinase-disintegrin-like batroxstatin-3 (EC ... Venom metalloproteinase (M12B) ...
VPA_BOTAT Venom prothrombin activator (vPA) (Fragment) Not in a family
VSPF_BOTAT Thrombin-like enzyme batroxobin (BX) (SVTLE) (EC 3.4.21.74) ... Peptidase S1 family, Snake venom ...