Bothrops jararacussu (jararacussu)



Venom composition image
Figure 1: Composition of B.jararacussu venom, studied at the transcriptomic level (Kashima et al., 2004 and Freitas-de-Sousa et al., 2020). The following families have been identified: PLA2 (phospholipase A2), SVMP (snake venom metalloproteinase), C-type lectin (true venom lectin), CRISP, serine protease (peptidase S1), L-amino-acid oxidase (flavin monoamine oxidase), nerve-growth factor (NGF-beta), BPP (bradykinin-potentiating peptide). "Other" corresponds to house keeping or no match sequences.
A. Venom composition of Bothrops jararacussu (Kashima et al., 2004). B. Venom composition of one of the smallest snakes in this study (BJSU04, 36 cm) of Freitas-de-Sousa et al., 2020. This study showed that basic myotoxic PLA2s are the most abundant components in large snakes, whereas in the venoms of small snakes, pro-coagulant and hemorrhagic PIII-class SVMPs are the major components. This variability was demonstrated to be linearly related to snake size and does not correspond to the reproductive stage or geographical location.
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Venom protein entries in UniProtKB/Swiss-Prot

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16 entries grouped by species (browse by taxonomy, browse by keywords)

16 entries

Bothrops jararacussu (Jararacussu)

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BNP_BOTJR Bradykinin-potentiating and C-type natriuretic peptides isoform ... Bradykinin-potentiating peptide ...
LECG_BOTJR C-type lectin BJcuL (CTL) (Galactose-specific lectin) (Snake ... True venom lectin family
NGFV_BOTJR Venom nerve growth factor (v-NGF) (vNGF) (Bj-NGF) NGF-beta family
OXLA_BOTJR L-amino-acid oxidase (BjsuLAAO) (BjussuLAAO-I) (LAO) (EC ... Flavin monoamine oxidase family, ...
PA2A_BOTJR Acidic phospholipase A2 BthA-1 (svPLA2) (EC 3.1.1.4) (BOJU-III) ... Phospholipase A2 family, Group ...
PA2B2_BOTJR Basic phospholipase A2 homolog bothropstoxin-II (Bothropstoxin ... Phospholipase A2 family, Group ...
PA2B_BOTJR Basic phospholipase A2 BjIV (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
PA2H1_BOTJR Basic phospholipase A2 homolog bothropstoxin-I (Bothropstoxin I) ... Phospholipase A2 family, Group ...
VM1B2_BOTJR Snake venom metalloproteinase BjussuMP-2 (SVMP) (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM3B1_BOTJR Zinc metalloproteinase-disintegrin-like BjussuMP-1 (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VSP1_BOTJR Thrombin-like enzyme BjussuSP-1 (SVTLE BjussuSP-1) (EC 3.4.21.-) ... Peptidase S1 family, Snake venom ...
VSP48_BOTJR Thrombin-like enzyme BJ-48 (SVTLE BJ-48) (EC 3.4.21.-) ... Peptidase S1 family, Snake venom ...
VSPDV_BOTJR Thrombin-like enzyme D-V (SVTLE D-V) (EC 3.4.21.-) (Clotting ... Peptidase S1 family, Snake venom ...
VSPH_BOTJR Snake venom serine protease homolog Peptidase S1 family, Snake venom ...
VVP1_BOTJR 1370.6 Da venom vasodilator peptide Not in a family
VVP2_BOTJR 1095.6 Da venom vasodilator peptide Not in a family