Bitis gabonica (Gaboon viper)


Venom composition
Figure 1: Composition of B.gabonica venom, studied at the proteomic level (Calvete et al., 2007 ). This venom contains the following families: CRISP, PLA2 (phospholipase A2 ), LAAO (L-amino-acid oxidase ), C-type lectin (true venom lectin and Snaclec ), SVMP (snake venom metalloproteinase ), serine protease, BPP (bradykinin potentiating peptide ), DC-fragment (disintegrin/cysteine-rich fragment from P-III SVMPs), disintegrin, venom Kunitz-type, cystatin, PDGF/VEGF growth factor.
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website
and the WHO venomous snake database to access snake distribution and antivenom products.
Lethal dose
Miscellaneous B. gabonica produces the largest amounts of venom of all poisonous snakes; yields in excess of 2 grams of dried venom per milking have been recorded.
There are comparatively few recorded cases of human snakebites, due in part to its nocturnal habits and its daytime concealment (Marsh et al., 1997 ).

Venom protein entries in UniProtKB/Swiss-Prot

15 entries grouped by species (browse by taxonomy, browse by keywords)

15 entries

Bitis gabonica (Gaboon adder) (Gaboon viper)

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CYT_BITGA Bitiscystatin (Cystatin) Cystatin family
DID1_BITGA Disintegrin gabonin-1 (Bitisgabonin-1) Disintegrin family, Dimeric ...
DID2_BITGA Disintegrin gabonin-2 (Bitisgabonin-2) Disintegrin family, Dimeric ...
LEC1_BITGA C-type lectin 1 (CTL) True venom lectin family
OXLA_BITGA L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) (Fragment) Flavin monoamine oxidase family, ...
PA2A_BITGA Acidic phospholipase A2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group ...
SL2_BITGA Snaclec 2 (C-type lectin 2) Snaclec family
SL3_BITGA Snaclec 3 (C-type lectin 3) Snaclec family
VEGFA_BITGA Vascular endothelial growth factor A (VEGF-A) (Vascular ... PDGF/VEGF growth factor family
VKT1_BITGA Kunitz-type serine protease inhibitor bitisilin-1 (BG-11) ... Venom Kunitz-type family
VKT2_BITGA Kunitz-type serine protease inhibitor bitisilin-2 (BG-15) ... Venom Kunitz-type family
VKT3_BITGA Kunitz-type serine protease inhibitor bitisilin-3 (Two-Kunitz ... Venom Kunitz-type family
VM2BI_BITGA Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VSP1_BITGA Venom serine proteinase-like protein 1 (Snake venom serine ... Peptidase S1 family, Snake venom ...
VSPG_BITGA Thrombin-like enzyme gabonase (SVTLE) (EC 3.4.21.55) ... Peptidase S1 family, Snake venom ...