Pharmacological target of venom proteins

This page gives the list of channel/receptor families that are targeted by venom proteins and an access to these venom proteins. A detailed information on these families is available by clicking on the "channel/receptor family" blue hyperlink, while clicking on the logo image permits to retrieve venom protein(s) of interest in UniProtKB/Swiss-Prot. Dashes indicate that no venom protein has been described yet to target the channel/receptor family.

The column "Channel/Receptor Human" of the table permits an access to human channel/receptor entries of UniProtKB/Swiss-Prot.


See also Venom protein activity
See also Systems targeted by venom proteins
See also Activity Greek symbol descriptors

Channel/receptor families Channel
Receptor
Venom proteins that target channels/receptors
Click on image to retrieve UniProtKB entries
Ion channel (voltage-gated and
ligand-gated)
Human Snake Scorpion Cone
snail
Spider Cnidarian Insect Other All
Voltage-gated sodium (Nav) channel image image image image image image image image image
Voltage-gated potassium (Kv) channel image image image image image image image image image
Calcium-activated potassium (KCa) channel image image image image image - image - image
Inward-rectifier potassium (KIR) channel image - image - - - image - image
Nicotinic acetylcholine receptor (nAChR) image image - image - - - - image
Voltage-gated calcium (Cav) channel image image image image image - image image image
Ryanodine-sensitive calcium-release (RyR) channel image image image - - - - image image
P2X receptor (P2RX) image - - - image - - - image
Voltage-gated chloride (ClC) channel image - image - - - - - image
CFTR channel image image image - - - - - image
Ionotropic GABA receptor image image - - - - - - image
Ionotropic glutamate receptor image - - image image - - - image
HCNa nonspecific cation channel image - - image - - - - image
Cyclic nucleotide-gated channel (CNG) image image - - - - - - image
Transient receptor potential (TRP) channel image - image - image image - image image
Acid-sensing ion channel (ASIC) image image - image image image image - image
5-HT receptor image - image image - - - - image
Ion channel (voltage-gated and
ligand-gated) ALL
image image image image image image image image image
receptor 7TM / G-protein coupled receptor (GPCR) Human/Insect Snake Scorpion Cone
snail
Spider Cnidarian Insect Other All
Adipokinetic hormone/corazonin-related peptide (ACP) receptor image - - - - - image - image
Adrenergic receptor image image image image - - - image image
Bradykinin receptor image image image - image - image image image
Cholecystokinin receptor image - - - - - - image image
Endothelin receptor image image - - - - - - image
Dopamine receptor image image - - - - - - image
GABA-B receptor image - - image - - - - image
Glucagon-like peptide receptor image - - - - - - image image
Melanocortin receptor image - image - image - - - image
Muscarinic acetylcholine receptor image image - - - - - - image
Neurotensin receptor image - - image - - - - image
Opioid receptor image image image - - - - image image
Prokineticin receptor image image - - - - - image image
Pruritogenic receptor MRGPRX1 image - - image - - - - image
Somatostatin receptor image - - image - - - - image
Vasoactive intestinal polypeptide receptor image - - - - - - image image
Vasopressin/oxytocin receptor image image - image - - - - image
receptor 7TM / G-protein coupled receptor (GPCR) ALL image image image image image - image image image
receptor 1TM Human Snake Scorpion Cone
snail
Spider Cnidarian Insect Other All
Epidermal growth factor receptor (EGFR) image - - - - image - - image
Insulin receptor (INSR) image - - image - - - - image
Integrin image image - - - - - - image
Vascular endothelial growth factor receptor (VEGFR) image image - - - - - - image
Transporter Human Snake Scorpion Cone
snail
Spider Cnidarian Insect Other All
Glutamate transporter image - - - image - - - image
Noradrenaline transporter image - - image - - - - image