Hemorrhagic toxin (Hemorrhagin)

Hemorrhagic toxins induce the leakage of blood components into tissues by damaging endothelial cells or disturbing endothelial cell interactions with the basement membrane.

See also UniProtKB-keyword.
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Venom protein entries in UniProtKB/Swiss-Prot

(all links/actions below point to uniprot.org website)

71 entries grouped by family

1 entry

Arthropod phospholipase D family, Class II subfamily, Class IIa sub-subfamily

A4A1_LOXIN Dermonecrotic toxin LiSicTox-alphaIVA1 (EC ... Loxosceles intermedia (Brown spider)

5 entries

Flavin monoamine oxidase family, FIG1 subfamily

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OXLA_AGKCL L-amino-acid oxidase (ACL-LAO) (LAAO) (EC ... Agkistrodon contortrix laticinctus (Broad-banded ...
OXLA_BOTAL L-amino-acid oxidase (Balt-LAAO-I) (LAO) (EC ... Bothrops alternatus (Urutu) (Rhinocerophis ...
OXLA_BOTPI L-amino-acid oxidase (BpirLAAO-I) (LAO) (EC ... Bothrops pirajai (Piraja's lancehead)
OXLA_CROAT L-amino-acid oxidase apoxin-1 (LAAO) (LAO) (EC ... Crotalus atrox (Western diamondback rattlesnake)
OXLA_GLOHA L-amino-acid oxidase (AHP-LAAO) (LAO) (EC ... Gloydius halys (Chinese water mocassin) ...

pdb 1REO; 1TDK; 1TDN; 1TDO

1 entry

Not in a family

ALPH_DEIAC Alkaline phosphatase (EC 3.1.3.1) Deinagkistrodon acutus (Hundred-pace snake) ...

2 entries

Phospholipase A2 family, Group I subfamily

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PA21_ACAPL Phospholipase A2 AP-PLA2-I (PLA2) (EC 3.1.1.4) ... Acanthaster planci (Crown-of-thorns starfish)
PA22_ACAPL Phospholipase A2 AP-PLA2-II (PLA2) (EC 3.1.1.4) ... Acanthaster planci (Crown-of-thorns starfish)

1 entry

Phospholipase A2 family, Group II subfamily, D49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2A2_VIPRE Acidic phospholipase A2 Vur-PL2B (Vur-PL2) ... Vipera renardi (Steppe viper) (Vipera ursinii ...

1 entry

True venom lectin family

"True venom lectin family" VenomZone page
LECJ3_BOTJA Jararafibrase-3 (EC 3.4.24.-) (Jararafibrase ... Bothrops jararaca (Jararaca) (Bothrops jajaraca)

2 entries

Venom metalloproteinase (M12B) family

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VMXJ4_BOTJA Snake venom metalloproteinase jararafibrase-4 ... Bothrops jararaca (Jararaca) (Bothrops jajaraca)
VMXP_PHIPA Snake venom metalloproteinase patagonfibrase ... Philodryas patagoniensis (Ringless green snake)

16 entries

Venom metalloproteinase (M12B) family, P-I subfamily

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VM11_BOTAT Snake venom metalloproteinase atroxlysin-1 ... Bothrops atrox (Barba amarilla) (Fer-de-lance)
VM11_DEIAC Snake venom metalloproteinase aculysin-1 (SVMP) ... Deinagkistrodon acutus (Hundred-pace snake) ...
VM1A3_DEIAC Snake venom metalloproteinase acutolysin-C ... Deinagkistrodon acutus (Hundred-pace snake) ...

pdb 1QUA

VM1AA_DEIAC Snake venom metalloproteinase acutolysin-A ... Deinagkistrodon acutus (Hundred-pace snake) ...

pdb 1BSW; 1BUD

VM1AC_CROAT Snake venom metalloproteinase atrolysin-C (SVMP) ... Crotalus atrox (Western diamondback rattlesnake)
VM1AC_DEIAC Snake venom metalloproteinase acutolysin-C ... Deinagkistrodon acutus (Hundred-pace snake) ...
VM1AD_CROAT Snake venom metalloproteinase atrolysin-D (SVMP) ... Crotalus atrox (Western diamondback rattlesnake)

pdb 1ATL; 1DTH; 1HTD

VM1AH_AGKCL Snake venom metalloproteinase ACLH (SVMP) (EC ... Agkistrodon contortrix laticinctus (Broad-banded ...
VM1B1_BOTAS Snake venom metalloproteinase BaP1 (SVMP) (EC ... Bothrops asper (Terciopelo)

pdb 1ND1; 2W12; 2W13; 2W14; 2W15

VM1B1_BOTAT Snake venom metalloproteinase Batx-1 (SVMP) (EC ... Bothrops atrox (Barba amarilla) (Fer-de-lance)
VM1CR_CROAT Snake venom metalloproteinase crotalin (SVMP) ... Crotalus atrox (Western diamondback rattlesnake)
VM1H2_CRORU Snake venom metalloproteinase HT-2 (SVMP) (EC ... Crotalus ruber ruber (Red diamond rattlesnake)
VM1H2_LACMU Snake venom metalloproteinase hemorrhagic factor ... Lachesis muta muta (Bushmaster)
VM1L4_MACLB Snake venom metalloproteinase lebetase-4 (Le-4) ... Macrovipera lebetina (Levantine viper) (Vipera ...
VM1RI_LACMR Snake venom metalloproteinase rhomb-I ... Lachesis muta rhombeata (Bushmaster)
VM1_BOTPI Snake venom metalloproteinase BpirMP (SVMP) (EC ... Bothrops pirajai (Piraja's lancehead)

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM25A_BITAR Zinc metalloproteinase-disintegrin BA-5A (EC ... Bitis arietans (African puff adder)

4 entries

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIa sub-subfamily

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VM2AE_CROAT Zinc metalloproteinase/disintegrin [Cleaved ... Crotalus atrox (Western diamondback rattlesnake)
VM2C1_CRODO Zinc metalloproteinase/disintegrin ... Crotalus durissus collilineatus (Brazilian ...
VM2HA_PROFL Zinc metalloproteinase/disintegrin [Cleaved ... Protobothrops flavoviridis (Habu) (Trimeresurus ...
VM2T3_PROMU Zinc metalloproteinase/disintegrin [Cleaved ... Protobothrops mucrosquamatus (Taiwan habu) ...

pdb 1KUF; 1KUG; 1KUI; 1KUK

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIb sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM2AG_GLOHA Zinc metalloproteinase-disintegrin agkistin (EC ... Gloydius halys (Chinese water mocassin) ...

2 entries

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIc sub-subfamily

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VM2B1_AGKBI Zinc metalloproteinase-disintegrin bilitoxin-1 ... Agkistrodon bilineatus (Cantil) (Tropical ...
VM2H1_BOTLA Zinc metalloproteinase-disintegrin BlatH1 (EC ... Bothriechis lateralis (Side-striped palm ...

2 entries

Venom metalloproteinase (M12B) family, P-III subfamily

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VM3_CROVE Zinc metalloproteinase-disintegrin-like ... Crotalus vegrandis (Uracoan rattlesnake) ...
VMH4A_VIPAA Zinc metalloproteinase-disintegrin-like protein ... Vipera ammodytes ammodytes (Western sand viper)

17 entries

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIa sub-subfamily

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VM31_BOTAT Zinc metalloproteinase-disintegrin-like ... Bothrops atrox (Barba amarilla) (Fer-de-lance)
VM33_BOTAT Zinc metalloproteinase-disintegrin-like ... Bothrops atrox (Barba amarilla) (Fer-de-lance)
VM3AA_CROAT Zinc metalloproteinase-disintegrin-like ... Crotalus atrox (Western diamondback rattlesnake)
VM3AH_DEIAC Zinc metalloproteinase-disintegrin-like ... Deinagkistrodon acutus (Hundred-pace snake) ...
VM3AL_BORPO Zinc metalloproteinase alsophinase (EC 3.4.24.-) ... Borikenophis portoricensis (Puerto Rican racer) ...
VM3B1_BOTJR Zinc metalloproteinase-disintegrin-like ... Bothrops jararacussu (Jararacussu)
VM3DK_DABRR Zinc metalloproteinase-disintegrin-like ... Daboia russelii (Russel's viper) (Vipera ...
VM3DM_DABSI Zinc metalloproteinase-disintegrin-like ... Daboia siamensis (Eastern Russel's viper) ...
VM3E2_ECHOC Zinc metalloproteinase-disintegrin-like EoVMP2 ... Echis ocellatus (Ocellated saw-scaled viper)
VM3H1_CRORU Snake venom metalloproteinase HT-1 (SVMP) (EC ... Crotalus ruber ruber (Red diamond rattlesnake)
VM3H3_BOTJA Zinc metalloproteinase-disintegrin-like HF3 (EC ... Bothrops jararaca (Jararaca) (Bothrops jajaraca)
VM3HA_GLOHA Zinc metalloproteinase-disintegrin-like halysase ... Gloydius halys (Chinese water mocassin) ...
VM3LB_BOTLC Zinc metalloproteinase leucurolysin-B (Leuc-B) ... Bothrops leucurus (Whitetail lancehead)
VM3_CRODD Zinc metalloproteinase-disintegrin-like (EC ... Crotalus durissus durissus (Central American ...
VM3_OPHHA Zinc metalloproteinase-disintegrin-like ohanin ... Ophiophagus hannah (King cobra) (Naja hannah)
VM3_PROJR Zinc metalloproteinase-disintegrin-like ... Protobothrops jerdonii (Jerdon's pitviper) ...
VM3_VIPAA Zinc metalloproteinase-disintegrin-like VaH1 (EC ... Vipera ammodytes ammodytes (Western sand viper)

6 entries

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIb sub-subfamily

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VM3A_BOTAL Zinc metalloproteinase-disintegrin-like ... Bothrops alternatus (Urutu) (Rhinocerophis ...
VM3BP_BOTJA Zinc metalloproteinase-disintegrin-like ... Bothrops jararaca (Jararaca) (Bothrops jajaraca)

pdb 3DSL

VM3H6_GLOBR Zinc metalloproteinase-disintegrin-like ... Gloydius brevicauda (Korean slamosa snake) ...
VM3HA_PROFL Zinc metalloproteinase/disintegrin-like HR1a (EC ... Protobothrops flavoviridis (Habu) (Trimeresurus ...
VM3HB_PROFL Zinc metalloproteinase-disintegrin-like HR1b (EC ... Protobothrops flavoviridis (Habu) (Trimeresurus ...
VM3JA_BOTJA Zinc metalloproteinase-disintegrin-like ... Bothrops jararaca (Jararaca) (Bothrops jajaraca)

9 entries

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIc sub-subfamily

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VM31_CRODC Zinc metalloproteinase-disintegrin-like ... Crotalus durissus cascavella (Northeastern ...
VM31_CRODU Zinc metalloproteinase-disintegrin-like ... Crotalus durissus terrificus (South American ...
VM31_LACMR Zinc metalloproteinase-disintegrin-like ... Lachesis muta rhombeata (Bushmaster)
VM32_BOTAT Zinc metalloproteinase-disintegrin-like ... Bothrops atrox (Barba amarilla) (Fer-de-lance)
VM32_LACMR Zinc metalloproteinase-disintegrin-like ... Lachesis muta rhombeata (Bushmaster)
VM3A_VIPAA Zinc metalloproteinase-disintegrin-like ... Vipera ammodytes ammodytes (Western sand viper)
VM3V1_CROAT Zinc metalloproteinase-disintegrin-like VAP1 (EC ... Crotalus atrox (Western diamondback rattlesnake)

pdb 2ERO; 2ERP; 2ERQ

VM3VA_CROAT Zinc metalloproteinase-disintegrin-like VAP2A ... Crotalus atrox (Western diamondback rattlesnake)
VMH3_VIPAA Zinc metalloproteinase-disintegrin-like protein ... Vipera ammodytes ammodytes (Western sand viper)