Fibrinogenolytic toxin

Fibrinogenolytic toxins are proteases involved in degradation of fibrinogen leading to a decrease of plasma fibrinogen concentration and ultimately reduced blood coagulation, thus facilitating the spread of the toxic components throughout the prey's circulation.

See also UniProtKB-keyword.

Venom protein entries in UniProtKB/Swiss-Prot

(all links/actions below point to uniprot.org website)

107 entries grouped by family

reorder by species

41 entries

Peptidase S1 family, Snake venom subfamily

"Peptidase S1 family" VenomZone page

VAE1_GLOHA Thrombin-like enzyme agkihpin-1 (TLE agkihpin-1) ... Gloydius halys (Chinese water mocassin) ...

VAE2_GLOHA Thrombin-like enzyme agkihpin-2 (TLE agkihpin-2) ... Gloydius halys (Chinese water mocassin) ...

VSP14_BOTJA Snake venom serine protease HS114 (SVSP) (EC ... Bothrops jararaca (Jararaca) (Bothrops jajaraca)

VSP1_BOTAN Thrombin-like enzyme TLBan (SVTLE TLBan) (EC ... Bothrocophias andianus (Andean lancehead) ...

VSP1_CRODM Thrombin-like enzyme Cdc SI (SVTLE) (EC ... Crotalus durissus cumanensis (South American ...

VSP1_GLOBL Thrombin-like enzyme halystase (SVTLE) (EC ... Gloydius blomhoffii (Mamushi) (Agkistrodon halys ...

VSP1_OPHHA Alpha- and beta-fibrinogenase OhS1 (EC 3.4.21.-) ... Ophiophagus hannah (King cobra) (Naja hannah)

VSP1_PROMU Beta-fibrinogenase mucrofibrase-1 (EC 3.4.21.-) ... Protobothrops mucrosquamatus (Taiwan habu) ...

VSP2_CRODM Thrombin-like enzyme Cdc SII (SVTLE) (EC ... Crotalus durissus cumanensis (South American ...

VSP2_LACMR Thrombin-like enzyme LmrSP-2 (SVTLE) (EC ... Lachesis muta rhombeata (Bushmaster)

VSP2_PROMU Beta-fibrinogenase mucrofibrase-2 (EC 3.4.21.-) ... Protobothrops mucrosquamatus (Taiwan habu) ...

VSP3_BOTJA Snake venom serine protease BPA (SVSP) (EC ... Bothrops jararaca (Jararaca) (Bothrops jajaraca)

VSP3_CROAT Alpha-fibrinogenase A3 (EC 3.4.21.-) (Snake ... Crotalus atrox (Western diamondback rattlesnake)

VSP3_LACMR Thrombin-like enzyme LmrSP-3 (SVTLE) (EC ... Lachesis muta rhombeata (Bushmaster)

VSP3_PROMU Beta-fibrinogenase mucrofibrase-3 (EC 3.4.21.-) ... Protobothrops mucrosquamatus (Taiwan habu) ...

VSP4_LACMR Snake venom serine protease LmrSP-4 (SVSP) (EC ... Lachesis muta rhombeata (Bushmaster)

VSP4_PROMU Beta-fibrinogenase mucrofibrase-4 (EC 3.4.21.-) ... Protobothrops mucrosquamatus (Taiwan habu) ...

VSP5_PROMU Beta-fibrinogenase mucrofibrase-5 (EC 3.4.21.-) ... Protobothrops mucrosquamatus (Taiwan habu) ...

VSPA1_CROAT Alpha-fibrinogenase A1 (EC 3.4.21.-) (Snake ... Crotalus atrox (Western diamondback rattlesnake)

VSPA2_CROAT Alpha-fibrinogenase A2 (EC 3.4.21.-) (Snake ... Crotalus atrox (Western diamondback rattlesnake)

VSPAA_CERCE Snake venom serine protease Afaacytin ... Cerastes cerastes (Horned desert viper)

VSPAF_DABSI Alpha-fibrinogenase-like (RVAF) (EC 3.4.21.-) ... Daboia siamensis (Eastern Russel's viper) ...

VSPAF_TRIAB Alpha-fibrinogenase albofibrase (EC 3.4.21.-) ... Trimeresurus albolabris (White-lipped pit viper) ...

VSPA_MACLB Alpha-fibrinogenase (VLAF) (EC 3.4.21.-) (Snake ... Macrovipera lebetina (Levantine viper) (Vipera ...

VSPBF_MACLB Beta-fibrinogenase (VLBF) (EC 3.4.21.-) (Snake ... Macrovipera lebetina (Levantine viper) (Vipera ...

VSPB_DABSI Beta-fibrinogenase-like (RVBF) (EC 3.4.21.-) ... Daboia siamensis (Eastern Russel's viper) ...

VSPB_GLOBL Beta-fibrinogenase brevinase (EC 3.4.21.-) ... Gloydius blomhoffii (Mamushi) (Agkistrodon halys ...

VSPC_TRIAB Thrombin-like enzyme chitribrisin (SVTLE ... Trimeresurus albolabris (White-lipped pit viper) ...

VSPF_LACMR Thrombin-like enzyme LMR-47 (SVTLE LM-47) (SVTLE ... Lachesis muta rhombeata (Bushmaster)

VSPHA_HYDHA Serine protease harobin (EC 3.4.21.-) ... Hydrophis hardwickii (Hardwick's spine-bellied ...

VSPI_GLOHA Thrombin-like enzyme AhV_TL-I (SVTLE AhV_TL-I) ... Gloydius halys (Chinese water mocassin) ...

pdb 4E7N

VSPJF_PROJR Beta-fibrinogenase jerdofibrase (EC 3.4.21.-) ... Protobothrops jerdonii (Jerdon's pitviper) ...

VSPJN_PROJR Snake venom serine protease jerdonase (SVSP) (EC ... Protobothrops jerdonii (Jerdon's pitviper) ...

VSPP_DEIAC Snake venom serine protease Dav-PA (SVSP) ... Deinagkistrodon acutus (Hundred-pace snake) ...

pdb 1OP0; 1OP2

VSPS1_TRIST Alpha- and beta-fibrinogenase stejnefibrase-1 ... Trimeresurus stejnegeri (Chinese green tree ...

VSPS2_TRIST Beta-fibrinogenase stejnefibrase-2 (EC 3.4.21.-) ... Trimeresurus stejnegeri (Chinese green tree ...

VSPSH_GLOSH Alpha-fibrinogenase shedaoenase (EC 3.4.21.-) ... Gloydius shedaoensis (Shedao island pit viper) ...

VSPY_MACLB Chymotrypsin-like protease VLCTLP (EC 3.4.21.-) ... Macrovipera lebetina (Levantine viper) (Vipera ...

VSP_BITAR Snake venom serine proteinase (SVSP) ... Bitis arietans (African puff adder)

VSP_BOTBA Thrombin-like enzyme barnettobin (Bb-TLE) ... Bothrops barnetti (Barnett's lancehead) ...

VSP_CRODC Thrombin-like enzyme F202 (SVTLE) (EC 3.4.21.-) ... Crotalus durissus cascavella (Northeastern ...

2 entries

Venom metalloproteinase (M12B) family

"Venom metalloproteinase (M12B) family" VenomZone page

VMPAR_HIPPR Zinc metalloproteinase partitagin (EC 3.4.24.-) Hippasa partita (Funnel-web spider) (Hippasa ...

VMXCA_CROAT Snake venom metalloproteinase catroxase (SVMP) ... Crotalus atrox (Western diamondback rattlesnake)

18 entries

Venom metalloproteinase (M12B) family, P-I subfamily

"Venom metalloproteinase (M12B) family" VenomZone page

VM11_BOTPA Snake venom metalloproteinase BpMP-1 (SVMP) (EC ... Bothrops pauloensis (Neuwied's lancehead) ...

VM1AH_AGKCL Snake venom metalloproteinase ACLH (SVMP) (EC ... Agkistrodon contortrix laticinctus (Broad-banded ...

VM1AT_CROAT Snake venom metalloproteinase atroxase (SVMP) ... Crotalus atrox (Western diamondback rattlesnake)

VM1B1_BOTAS Snake venom metalloproteinase BaP1 (SVMP) (EC ... Bothrops asper (Terciopelo)

pdb 1ND1; 2W12; 2W13; 2W14; 2W15

VM1B1_BOTAT Snake venom metalloproteinase Batx-1 (SVMP) (EC ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

VM1B1_BOTBA Zinc metalloproteinase barnettlysin-1 (EC ... Bothrops barnetti (Barnett's lancehead) ...

VM1B1_BOTPA Snake venom metalloproteinase BnP1 (SVMP) (EC ... Bothrops pauloensis (Neuwied's lancehead) ...

VM1B2_BOTPA Snake venom metalloproteinase BnP2 (SVMP) (EC ... Bothrops pauloensis (Neuwied's lancehead) ...

VM1BI_BOTMO Snake venom metalloproteinase BmooMPalpha-I ... Bothrops moojeni (Lance-headed viper) (Caissaca)

pdb 3GBO

VM1BJ_BOTJA Snake venom metalloproteinase bothrojaractivase ... Bothrops jararaca (Jararaca) (Bothrops jajaraca)

VM1B_BOTLC Snake venom metalloproteinase BleucMP (SVMP) (EC ... Bothrops leucurus (Whitetail lancehead)

VM1CR_CROAT Snake venom metalloproteinase crotalin (SVMP) ... Crotalus atrox (Western diamondback rattlesnake)

VM1F_MACLB Snake venom metalloproteinase fibrolase (SVMP) ... Macrovipera lebetina (Levantine viper) (Vipera ...

VM1H1_BOTMA Snake venom metalloproteinase HF-1 (BmHF-1) ... Bothrops marajoensis (Marajo lancehead)

VM1L4_MACLB Snake venom metalloproteinase lebetase-4 (Le-4) ... Macrovipera lebetina (Levantine viper) (Vipera ...

VM1N_BOTPA Snake venom metalloproteinase neuwiedase (SVMP) ... Bothrops pauloensis (Neuwied's lancehead) ...

VM1V1_AGKPL Snake venom metalloproteinase VMP1 (AplVMP-I) ... Agkistrodon piscivorus leucostoma (Western ...

VM1_BOTPI Snake venom metalloproteinase BpirMP (SVMP) (EC ... Bothrops pirajai (Piraja's lancehead)

2 entries

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIa sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page

VM2A_CROAT Snake venom metalloproteinase CatroxMP-II (SVMP) ... Crotalus atrox (Western diamondback rattlesnake)

VM2T3_PROMU Zinc metalloproteinase/disintegrin [Cleaved ... Protobothrops mucrosquamatus (Taiwan habu) ...

pdb 1KUF; 1KUG; 1KUI; 1KUK

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIb sub-subfamily

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIc sub-subfamily

2 entries

Venom metalloproteinase (M12B) family, P-II subfamily, P-IId sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page

VM2MC_GLOBR Zinc metalloproteinase/disintegrin [Cleaved ... Gloydius brevicauda (Korean slamosa snake) ...

VM2MD_GLOBR Zinc metalloproteinase/disintegrin [Cleaved ... Gloydius brevicauda (Korean slamosa snake) ...

2 entries

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIe sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page

VM2L2_MACLB Zinc metalloproteinase/disintegrin [Cleaved ... Macrovipera lebetina (Levantine viper) (Vipera ...

VM2V2_AGKPL Zinc metalloproteinase/disintegrin VMP-II ... Agkistrodon piscivorus leucostoma (Western ...

3 entries

Venom metalloproteinase (M12B) family, P-III subfamily

"Venom metalloproteinase (M12B) family" VenomZone page

VM3A2_DEIAC Zinc metalloproteinase recombinant fibrinogenase ... Deinagkistrodon acutus (Hundred-pace snake) ...

VM3_CROVE Zinc metalloproteinase-disintegrin-like ... Crotalus vegrandis (Uracoan rattlesnake) ...

VMH4A_VIPAA Zinc metalloproteinase-disintegrin-like protein ... Vipera ammodytes ammodytes (Western sand viper)

18 entries

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIa sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page

VM31_BOTAT Zinc metalloproteinase-disintegrin-like ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

VM32A_GLOBR Zinc metalloproteinase-disintegrin-like ... Gloydius brevicauda (Korean slamosa snake) ...

VM32B_GLOBR Zinc metalloproteinase-disintegrin-like ... Gloydius brevicauda (Korean slamosa snake) ...

VM33_BOTAT Zinc metalloproteinase-disintegrin-like ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

VM3AH_NAJAT Zinc metalloproteinase atrahagin (EC 3.4.24.-) ... Naja atra (Chinese cobra)

VM3AL_BORPO Zinc metalloproteinase alsophinase (EC 3.4.24.-) ... Borikenophis portoricensis (Puerto Rican racer) ...

VM3B1_BOTJR Zinc metalloproteinase-disintegrin-like ... Bothrops jararacussu (Jararacussu)

VM3BA_BOTAS Snake venom metalloproteinase basparin-A (SVMP) ... Bothrops asper (Terciopelo)

VM3B_NAJAT Zinc metalloproteinase-disintegrin-like atrase-B ... Naja atra (Chinese cobra)

VM3DK_DABRR Zinc metalloproteinase-disintegrin-like ... Daboia russelii (Russel's viper) (Vipera ...

VM3DM_DABSI Zinc metalloproteinase-disintegrin-like ... Daboia siamensis (Eastern Russel's viper) ...

VM3LB_BOTLC Zinc metalloproteinase leucurolysin-B (Leuc-B) ... Bothrops leucurus (Whitetail lancehead)

VM3_BUNFA Zinc metalloproteinase-disintegrin-like BfMP (EC ... Bungarus fasciatus (Banded krait) (Pseudoboa ...

VM3_BUNMU Zinc metalloproteinase-disintegrin-like BmMP (EC ... Bungarus multicinctus (Many-banded krait)

VM3_NAJAT Zinc metalloproteinase-disintegrin-like NaMP (EC ... Naja atra (Chinese cobra)

VM3_OPHHA Zinc metalloproteinase-disintegrin-like ohanin ... Ophiophagus hannah (King cobra) (Naja hannah)

VM3_VIPAA Zinc metalloproteinase-disintegrin-like VaH1 (EC ... Vipera ammodytes ammodytes (Western sand viper)

VMF1_VIPAA Zinc metalloproteinase-disintegrin-like protein ... Vipera ammodytes ammodytes (Western sand viper)

4 entries

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIb sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page

VM3AL_TRIAB Zinc metalloproteinase-disintegrin-like ... Trimeresurus albolabris (White-lipped pit viper) ...

VM3H6_GLOBR Zinc metalloproteinase-disintegrin-like ... Gloydius brevicauda (Korean slamosa snake) ...

VM3JA_BOTJA Zinc metalloproteinase-disintegrin-like ... Bothrops jararaca (Jararaca) (Bothrops jajaraca)

VM3_BOTMO Zinc metalloproteinase-disintegrin-like moojenin ... Bothrops moojeni (Lance-headed viper) (Caissaca)

13 entries

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIc sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page

VM31_CRODC Zinc metalloproteinase-disintegrin-like ... Crotalus durissus cascavella (Northeastern ...

VM31_CRODU Zinc metalloproteinase-disintegrin-like ... Crotalus durissus terrificus (South American ...

VM31_LACMR Zinc metalloproteinase-disintegrin-like ... Lachesis muta rhombeata (Bushmaster)

VM32_BOTAT Zinc metalloproteinase-disintegrin-like ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

VM32_LACMR Zinc metalloproteinase-disintegrin-like ... Lachesis muta rhombeata (Bushmaster)

VM3A_VIPAA Zinc metalloproteinase-disintegrin-like ... Vipera ammodytes ammodytes (Western sand viper)

VM3E1_ECHOC Zinc metalloproteinase-disintegrin-like Eoc1 (EC ... Echis ocellatus (Ocellated saw-scaled viper)

VM3H1_PROFL Zinc metalloproteinase-disintegrin-like HV1 (EC ... Protobothrops flavoviridis (Habu) (Trimeresurus ...

VM3TM_TRIST Zinc metalloproteinase-disintegrin-like TSV-DM ... Trimeresurus stejnegeri (Chinese green tree ...

VM3V1_CROAT Zinc metalloproteinase-disintegrin-like VAP1 (EC ... Crotalus atrox (Western diamondback rattlesnake)

pdb 2ERO; 2ERP; 2ERQ

VM3VA_MACLB Zinc metalloproteinase-disintegrin-like VLAIP-A ... Macrovipera lebetina (Levantine viper) (Vipera ...

VM3VB_MACLB Zinc metalloproteinase-disintegrin-like VLAIP-B ... Macrovipera lebetina (Levantine viper) (Vipera ...

VMH3_VIPAA Zinc metalloproteinase-disintegrin-like protein ... Vipera ammodytes ammodytes (Western sand viper)

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