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Channel/receptor | Descriptor | Biological function associated with descriptor |
Ion channel (voltage-gated and ligand-gated) | ||
Voltage-gated sodium (Nav) channel & | β (beta) | Shifts voltage-dependence of Nav channel activation |
Voltage-gated sodium (Nav) channel & | δ (delta) | Delays inactivation of voltage-activated Nav channels |
Voltage-gated sodium (Nav) channel & | ι (iota) | Nav channel agonist |
Voltage-gated sodium (Nav) channel & | μ (mu) | Inhibits voltage-activated sodium (Nav) channels |
Voltage-gated potassium (Kv) channel | κ (kappa) | Inhibits voltage-activated potassium (Kv) channels |
Calcium-activated potassium (KCa) channel | λ (lambda) | Inhibits calcium-activated potassium (KCa) channels |
Inward-rectifier potassium (KIR) channel | η (eta) | |
Nicotinic acetylcholine receptor (nAChR) # | α (alpha) | Targets acetylcholine receptor |
Nicotinic acetylcholine receptor (nAChR) # | ψ (psi) | Noncompetitive antagonist of acetylcholine receptor |
Voltage-gated calcium (Cav) channel | ω (omega) | Inhibits voltage-gated calcium (Cav) channels |
Ryanodine-sensitive calcium-release (RyR) channel | φ (phi) | |
P2X receptor (P2RX) | Ο (OMICRON) | |
Voltage-gated chloride (ClC) channel | ε (epsilon) | |
CFTR channel | Σ (SIGMA) | |
Ionotropic GABA receptor | Λ (LAMBDA) | |
Ionotropic glutamate receptor | Γ (GAMMA) | |
HCNa nonspecific cation channel | γ (gamma) | |
Cyclic nucleotide-gated channel (CNG) | ζ (zeta) | |
Transient receptor potential (TRP) channel | τ (tau) | |
Acid-sensing ion (ASICs) channel (ACCN) | π (pi) | |
5-HT receptor | σ (sigma) | |
receptor 7TM / G-protein coupled receptor (GPCR) | ||
Adrenergic receptor | ρ (rho) | |
Bradykinin receptor | ||
Cholecystokinin receptor | ||
Endothelin receptor | ξ (xi) | |
Dopamine receptor | ||
Glucagon-like peptide receptor | ||
Muscarinic acetylcholine receptor | ||
Neurotensin receptor | ν (nu) | |
Opioid receptor | ||
Somatostatin receptor | ||
Vasoactive intestinal polypeptide receptor | ||
Vasopressin/oxytocin receptor | υ (upsilon) | |
receptor 1TM | ||
Vascular endothelial growth factor receptor (VEGFR) | ||
Epidermal growth factor receptor (EGFR) | Ω (OMEGA) | |
Transporter | ||
Noradrenaline transporter | χ (chi) | |
Glutamate transporter | ||
Other activity | ||
Phospholipase A2 activity | A2 | |
Cytolytic activity | Δ (DELTA) | |
Antimicrobial activity | M | |
Protease inhibition | PI | |
Unknown activity | U | |
Activity for which no toxin has been discovered yet | Two-pore domain potassium (K2P) channel (KCNK) | θ (theta) |
Octopamine receptor | ο (omicron) |