Agkistrodon piscivorus leucostoma (Western cottonmouth)

Venom composition
Figure 1: Composition of A.p.leucostoma venom, studied at proteomic level (Lomonte, et al., 2014 ). This venom contains the following families: SVMP (venom metalloproteinase ), serine protease (peptidase S1 ), peptides (include tripeptide SVMP inhibitors and bradykinin-potentiating and bradykinin-inhibitory peptides), LAAO (L-amino-acid oxidase (flavin monoamine oxidase) ), disintegrin, snaclec (also known as C-type lectin-like), CRISP, PA2 (phospholipase A2 ).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website
and the WHO venomous snake database to access snake distribution and antivenom products.
Lethal dose LD(50) of A.piscivorus is
6.24 mg/kg by intraperitoneal injection and
5.13 mg/kg by intravenous injection (Arce et al., 2003 ).

Venom protein entries in UniProtKB/Swiss-Prot

8 entries grouped by family (browse by taxonomy, browse by keywords)

1 entry

Disintegrin family, Dimeric disintegrin subfamily

"Disintegrin family" VenomZone page
DIDA_AGKPL Disintegrin subunit alpha Agkistrodon piscivorus leucostoma (Western ...

2 entries

Peptidase S1 family, Snake venom subfamily

Select_allDeselect_all "Peptidase S1 family" VenomZone page
VSPCA_AGKPL Protein C activator (APL-C) (EC 3.4.21.-) (Snake ... Agkistrodon piscivorus leucostoma (Western ...
VSPPA_AGKPL Venom plasminogen activator (APL-PA) (EC ... Agkistrodon piscivorus leucostoma (Western ...

1 entry

Phospholipase A2 family, Group II subfamily, D49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2B1_AGKPL Basic phospholipase A2 APL-D49 (svPLA2) (EC ... Agkistrodon piscivorus leucostoma (Western ...

1 entry

Phospholipase A2 family, Group II subfamily, K49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2HB_AGKPL Basic phospholipase A2 homolog (svPLA2 homolog) ... Agkistrodon piscivorus leucostoma (Western ...

1 entry

Venom metalloproteinase (M12B) family, P-I subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM1V1_AGKPL Snake venom metalloproteinase VMP1 (AplVMP-I) ... Agkistrodon piscivorus leucostoma (Western ...

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIe sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM2V2_AGKPL Zinc metalloproteinase/disintegrin VMP-II ... Agkistrodon piscivorus leucostoma (Western ...

1 entry

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIa sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM3V3_AGKPL Zinc metalloproteinase-disintegrin-like VMP-III ... Agkistrodon piscivorus leucostoma (Western ...