Agkistrodon piscivorus leucostoma (Western cottonmouth)

Venom composition image
Figure 1: Composition of A.p.leucostoma venom, studied at proteomic level (Lomonte, et al., 2014). This venom contains the following families: SVMP (venom metalloproteinase), serine protease (peptidase S1), peptides (include tripeptide SVMP inhibitors and bradykinin-potentiating and bradykinin-inhibitory peptides), LAAO (L-amino-acid oxidase (flavin monoamine oxidase) ), disintegrin, snaclec (also known as C-type lectin-like), CRISP, PA2 (phospholipase A2).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website.
Lethal dose LD(50) of A.piscivorus is
6.24 mg/kg by intraperitoneal injection and
5.13 mg/kg by intravenous injection (Arce et al., 2003).

Venom protein entries in UniProtKB/Swiss-Prot

(all links/actions below point to uniprot.org website)

9 entries grouped by family (browse by taxonomy, browse by keywords)

1 entry

Disintegrin family, Dimeric disintegrin subfamily

"Disintegrin family" VenomZone page
DIDA_AGKPL Disintegrin subunit alpha Agkistrodon piscivorus leucostoma (Western ...

2 entries

Peptidase S1 family, Snake venom subfamily

Select_allDeselect_all "Peptidase S1 family" VenomZone page
VSPCA_AGKPL Protein C activator (APL-C) (EC 3.4.21.-) (Snake ... Agkistrodon piscivorus leucostoma (Western ...
VSPPA_AGKPL Venom plasminogen activator (APL-PA) (EC ... Agkistrodon piscivorus leucostoma (Western ...

2 entries

Phospholipase A2 family, Group II subfamily, D49 sub-subfamily

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PA21_AGKPL Acidic phospholipase A2 AplTX-I (svPLA2) (EC ... Agkistrodon piscivorus leucostoma (Western ...
PA2B1_AGKPL Basic phospholipase A2 APL-D49 (svPLA2) (EC ... Agkistrodon piscivorus leucostoma (Western ...

1 entry

Phospholipase A2 family, Group II subfamily, K49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2HB_AGKPL Basic phospholipase A2 homolog APL-K49 (svPLA2 ... Agkistrodon piscivorus leucostoma (Western ...

1 entry

Venom metalloproteinase (M12B) family, P-I subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM1V1_AGKPL Snake venom metalloproteinase VMP1 (AplVMP-I) ... Agkistrodon piscivorus leucostoma (Western ...

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIe sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM2V2_AGKPL Zinc metalloproteinase/disintegrin VMP-II ... Agkistrodon piscivorus leucostoma (Western ...

1 entry

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIa sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM3V3_AGKPL Zinc metalloproteinase-disintegrin-like VMP-III ... Agkistrodon piscivorus leucostoma (Western ...