Bothrops pauloensis (Neuwied's lancehead) (taxid:1042543)

Venom composition

Figure 1: Composition of B.pauloensis venom, studied at the proteomic level (A) and at the transcriptomic level (B) (Rodrigues etal., 2012). The following families are represented: CRISP, PLA2 (phospholipase A2), LAAO (L-amino-acid oxidase), true venom lectin, SVMP (snake venom metalloproteinase), serine protease, BPP-natriuretic peptide (bradykinin-potentiating peptide and natriuretic peptide), NGF-beta, ohanin/vespryn, 5'-nucleotidase, hyaluronidase (glycosyl hydrolase 56), svVEGF (PDGF/VEGF growth factor), disintegrin.
Calvete et al., 2009 also describes the characterization of the venom proteome of B.Pauloensis. CRISP and PLA2 families are most abundant in this study, whereas serine protease BPP-natriuretic peptide families are less abundant.

Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website.

Lethal dose

Taxonomy

UniProt taxonomy
The Reptile database
Wikipedia missing

Infraorder:	Serpentes

Family:	Viperidae
Genus:	Bothrops
Species:	pauloensis

Activity Antimicrobial
Hemostasis impairing toxin
Blood coagulation cascade activating toxin
Blood coagulation cascade inhibiting toxin
Fibrinogenolytic toxin
Fibrinolytic toxin
Platelet agg. activating toxin
Myotoxin
Neurotoxin
Presynaptic neurotoxin
or see
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Some history Neuwied's lancehead, a B.pauloensis patronym honoring Prince Alexander Philipp Maximilian zu Wied-Neuwied (1782?1867), the German explorer and naturalist,who led an expedition to southeast Brazil from 1815 to 1817, and found the tribe of the Botocudos, about which he gave exact details for the first time.

Reference Rodrigues et al., 2012

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Bothrops pauloensis (Neuwied's lancehead) (taxid:1042543)

Venom protein entries in UniProtKB/Swiss-Prot

Flavin monoamine oxidase family, FIG1 subfamily

Peptidase S1 family, Snake venom subfamily

Phospholipase A2 family, Group II subfamily, D49 sub-subfamily

Phospholipase A2 family, Group II subfamily, K49 sub-subfamily

True venom lectin family

Venom metalloproteinase (M12B) family, P-I subfamily