Bitis gabonica (Gaboon viper) (taxid:8694)


Venom composition image
Figure 1: Composition of B.gabonica venom, studied at the proteomic level (Calvete et al., 2007). This venom contains the following families: CRISP, PLA2 (phospholipase A2), LAAO (L-amino-acid oxidase), C-type lectin (true venom lectin and Snaclec), SVMP (snake venom metalloproteinase), serine protease, BPP (bradykinin potentiating peptide), DC-fragment (disintegrin/cysteine-rich fragment from P-III SVMPs), disintegrin, venom Kunitz-type, cystatin, PDGF/VEGF growth factor.
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website.
Miscellaneous B. gabonica produces the largest amounts of venom of all poisonous snakes; yields in excess of 2 grams of dried venom per milking have been recorded.
There are comparatively few recorded cases of human snakebites, due in part to its nocturnal habits and its daytime concealment (Marsh et al., 1997).
Taxonomy

UniProt taxonomy
The Reptile database
Wikipedia

Infraorder: Serpentes


Family: Viperidae
Genus: Bitis
Species: gabonica
Activity Hemostasis impairing toxin
  Blood coagulation cascade activating toxin
or see
UniProtKB browsing by keyword
Reference Francischetti et al., 2004
Calvete et al., 2007

Venom protein entries in UniProtKB/Swiss-Prot

(all links/actions below point to uniprot.org website)

15 entries grouped by family

1 entry

Cystatin family

"Cystatin family" VenomZone page
CYT_BITGA Bitiscystatin (Cystatin) Bitis gabonica (Gaboon adder) (Gaboon viper)

2 entries

Disintegrin family, Dimeric disintegrin subfamily

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DID1_BITGA Disintegrin gabonin-1 (Bitisgabonin-1) Bitis gabonica (Gaboon adder) (Gaboon viper)
DID2_BITGA Disintegrin gabonin-2 (Bitisgabonin-2) Bitis gabonica (Gaboon adder) (Gaboon viper)

1 entry

Flavin monoamine oxidase family, FIG1 subfamily

"Flavin monoamine oxidase family" VenomZone page
OXLA_BITGA L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) Bitis gabonica (Gaboon adder) (Gaboon viper)

1 entry

PDGF/VEGF growth factor family

"PDGF/VEGF growth factor family" VenomZone page
VEGFA_BITGA Vascular endothelial growth factor A (VEGF-A) ... Bitis gabonica (Gaboon adder) (Gaboon viper)

2 entries

Peptidase S1 family, Snake venom subfamily

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VSPG_BITGA Thrombin-like enzyme gabonase (SVTLE) (EC ... Bitis gabonica (Gaboon adder) (Gaboon viper)
VSPH1_BITGA Snake venom serine protease homolog 1 (Venom ... Bitis gabonica (Gaboon adder) (Gaboon viper)

1 entry

Phospholipase A2 family, Group II subfamily, D49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2A_BITGA Acidic phospholipase A2 (svPLA2) (EC 3.1.1.4) ... Bitis gabonica (Gaboon adder) (Gaboon viper)

2 entries

Snaclec family

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SL2_BITGA Snaclec 2 (C-type lectin 2) Bitis gabonica (Gaboon adder) (Gaboon viper)
SL3_BITGA Snaclec 3 (C-type lectin 3) Bitis gabonica (Gaboon adder) (Gaboon viper)

1 entry

True venom lectin family

"True venom lectin family" VenomZone page
LEC1_BITGA C-type lectin 1 (CTL) Bitis gabonica (Gaboon adder) (Gaboon viper)

3 entries

Venom Kunitz-type family

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VKT1_BITGA Kunitz-type serine protease inhibitor ... Bitis gabonica (Gaboon adder) (Gaboon viper)
VKT2_BITGA Kunitz-type serine protease inhibitor ... Bitis gabonica (Gaboon adder) (Gaboon viper)
VKT3_BITGA Kunitz-type serine protease inhibitor ... Bitis gabonica (Gaboon adder) (Gaboon viper)

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIe sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM2BI_BITGA Zinc metalloproteinase/disintegrin [Cleaved ... Bitis gabonica (Gaboon adder) (Gaboon viper)