Naja atra (Chinese cobra)


Venom composition
Figure 1: Composition of N. atra venom, studied at the transcriptomic level. This venom contains the following families: 3FT (snake three-finger toxin ), NGF (NGF-beta ), LAAO (flavin monoamine oxidase (L-amino-acid oxidase) ), ohanin/vespryn , CRISP, lectin (true venom lectin ), kunitz (venom Kunitz-type ), PA2 (phospholipase A2 ), cystatin, metalloproteinase (venom metalloproteinase ) (Jiang et al., 2011 ).
Cathelicidin, natriuretic peptide, and peptidase S1 (serine protease) have not been observed in this study, but these proteins have been described in this venom (Zhao et al., 2008, Zhan et al., 2011, and Jin et al., 2007 ).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website (Postsynaptic neurotoxins)
and the WHO venomous snake database to access snake distribution and antivenom products.
Lethal dose LD(50) is 0.29 mg/kg when subcutaneously injected (Jiang et al., 2011 ).

Venom protein entries in UniProtKB/Swiss-Prot

62 entries grouped by family (browse by taxonomy, browse by keywords)

1 entry

Cathelicidin family

"Cathelicidin family" VenomZone page
CAMP_NAJAT Cathelicidin-related peptide Na_CRAMP ... Naja atra (Chinese cobra)

2 entries

CRISP family

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CRVP1_NAJAT Cysteine-rich venom protein natrin-1 ... Naja atra (Chinese cobra)
CRVP2_NAJAT Cysteine-rich venom protein natrin-2 ... Naja atra (Chinese cobra)

1 entry

Cystatin family

"Cystatin family" VenomZone page
CYT_NAJAT Cystatin (Fragment) Naja atra (Chinese cobra)

1 entry

Flavin monoamine oxidase family, FIG1 subfamily

"Flavin monoamine oxidase family" VenomZone page
OXLA_NAJAT L-amino-acid oxidase (LAAO) (LAO) (NA-LAAO) (EC ... Naja atra (Chinese cobra)

1 entry

Natriuretic peptide family

"Natriuretic peptide family" VenomZone page
VNP_NAJAT Natriuretic peptide Na-NP Naja atra (Chinese cobra)

1 entry

NGF-beta family

"NGF-beta family" VenomZone page
NGFV_NAJAT Venom nerve growth factor (v-NGF) (vNGF) Naja atra (Chinese cobra)

1 entry

Peptidase S1 family, Snake venom subfamily

"Peptidase S1 family" VenomZone page
VSP1_NAJAT Snake venom serine protease NaSP (SVSP) (EC ... Naja atra (Chinese cobra)

3 entries

Phospholipase A2 family, Group I subfamily, D49 sub-subfamily

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PA2A1_NAJAT Acidic phospholipase A2 1 (svPLA2) (EC 3.1.1.4) ... Naja atra (Chinese cobra)
PA2A2_NAJAT Acidic phospholipase A2 2 (svPLA2) (EC 3.1.1.4) ... Naja atra (Chinese cobra)
PA2A_NAJAT Acidic phospholipase A2 natratoxin (svPLA2) (EC ... Naja atra (Chinese cobra)

5 entries

Snake three-finger toxin family, Non-conventional subfamily, Orphan group II sub-subfamily

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3NO21_NAJAT Probable weak neurotoxin NNAM1 Naja atra (Chinese cobra)
3NO22_NAJAT Probable weak neurotoxin NNAM2 (TA-N9) Naja atra (Chinese cobra)
3NO23_NAJAT Probable weak neurotoxin NNAM3 Naja atra (Chinese cobra)
3NO2H_NAJAT Long neurotoxin homolog (Kappa-cobrotoxin) Naja atra (Chinese cobra)
3NO2I_NAJAT Probable weak neurotoxin NNAM2I Naja atra (Chinese cobra)

1 entry

Snake three-finger toxin family, Short-chain subfamily, Orphan group I sub-subfamily

"Snake three-finger toxin family" VenomZone page
3SO1_NAJAT Neurotoxin-like protein NTL2 Naja atra (Chinese cobra)

1 entry

Snake three-finger toxin family, Short-chain subfamily, Orphan group VIII (haditoxin) sub-subfamily

"Snake three-finger toxin family" VenomZone page
3SO8_NAJAT Neurotoxin homolog NL1 Naja atra (Chinese cobra)

8 entries

Snake three-finger toxin family, Short-chain subfamily, Orphan group XV sub-subfamily

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3SOF3_NAJAT Cytotoxin homolog Clbp-3 (Cardiotoxin-like basic ... Naja atra (Chinese cobra)
3SOF5_NAJAT Cytotoxin A5 (CTX A5) (CT A5) (Cardiotoxin A5) ... Naja atra (Chinese cobra)
3SOF7_NAJAT Cytotoxin 7 (Cardiotoxin-7) (CTX7) (Ctx-7) ... Naja atra (Chinese cobra)
3SOFA_NAJAT Cardiotoxin 7a Naja atra (Chinese cobra)
3SOFH_NAJAT Cardiotoxin-like basic polypeptide ah (CLBPah) ... Naja atra (Chinese cobra)
3SOFL_NAJAT Cytotoxin homolog 5 (Cardiotoxin V-like) Naja atra (Chinese cobra)
3SOFP_NAJAT Cardiotoxin 7'' (Cardiotoxin 7') (Cardiotoxin ... Naja atra (Chinese cobra)
3SOFV_NAJAT Cytotoxin homolog 5V (Cardiotoxin-5V) (CTX5V) Naja atra (Chinese cobra)

2 entries

Snake three-finger toxin family, Short-chain subfamily, Type I alpha-neurotoxin sub-subfamily

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3S1CB_NAJAT Cobrotoxin (CBT) (Atratoxin) (Short neurotoxin ... Naja atra (Chinese cobra)
3S1CC_NAJAT Cobrotoxin-b (CBT-b) (Atratoxin-b) (Cobrotoxin ... Naja atra (Chinese cobra)

27 entries

Snake three-finger toxin family, Short-chain subfamily, Type IA cytotoxin sub-subfamily

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3SA1A_NAJAT Cytotoxin 1a (Cardiotoxin-1a) Naja atra (Chinese cobra)
3SA1B_NAJAT Cytotoxin 1b (Cardiotoxin-1b) Naja atra (Chinese cobra)
3SA1C_NAJAT Cytotoxin 1c (Cardiotoxin-1c) Naja atra (Chinese cobra)
3SA1D_NAJAT Cytotoxin 1d/1e (Cardiotoxin-1d/1e) Naja atra (Chinese cobra)
3SA1F_NAJAT Cytotoxin 1f (Cardiotoxin 1f) (Fragment) Naja atra (Chinese cobra)
3SA1_NAJAT Cytotoxin 1 (CX1) (Cardiotoxin 1) (CTX-1) (CTX1) ... Naja atra (Chinese cobra)
3SA2_NAJAT Cytotoxin 2 (Cardiotoxin 1A) (Cardiotoxin 2) ... Naja atra (Chinese cobra)
3SA3A_NAJAT Cytotoxin 3a (Cardiotoxin-31) (Ctx-31) ... Naja atra (Chinese cobra)
3SA3B_NAJAT Cytotoxin 3b (Cardiotoxin 3b) Naja atra (Chinese cobra)
3SA3D_NAJAT Cytotoxin 3d (Cardiotoxin 3d) Naja atra (Chinese cobra)
3SA3_NAJAT Cytotoxin 3 (Cardiotoxin 3) (CTX-3) (CTX3) ... Naja atra (Chinese cobra)
3SA4N_NAJAT Cytotoxin 4N (Cardiotoxin-4N) (CTX-4N) Naja atra (Chinese cobra)
3SA4_NAJAT Cytotoxin 4 (CTX-4M) (CTX4) (Cardiotoxin A4) ... Naja atra (Chinese cobra)
3SA5_NAJAT Cytotoxin 5 (Cardiotoxin 5) (CTX5) Naja atra (Chinese cobra)
3SA6_NAJAT Cytotoxin 6 (Cardiotoxin-6) (CTX6) Naja atra (Chinese cobra)
3SA8A_NAJAT Cytotoxin 8 (Cardiotoxin-8) (CTX8) Naja atra (Chinese cobra)
3SA8B_NAJAT Cytotoxin 8 (Cardiotoxin VIII) (Cardiotoxin-8) ... Naja atra (Chinese cobra)
3SAA_NAJAT Cytotoxin 10 (Cardiotoxin-10) (CTX10) (Ctx-10) Naja atra (Chinese cobra)
3SADB_NAJAT Cytotoxin SP13b Naja atra (Chinese cobra)
3SAFA_NAJAT Cytotoxin SP15a Naja atra (Chinese cobra)
3SAFC_NAJAT Cytotoxin SP15c Naja atra (Chinese cobra)
3SAFD_NAJAT Cytotoxin SP15d Naja atra (Chinese cobra)
3SAG_NAJAT Cytotoxin najalgesin (Fragment) Naja atra (Chinese cobra)
3SAN_NAJAT Cytotoxin 6 (Cardiotoxin 6) (CTX6) (Cardiotoxin ... Naja atra (Chinese cobra)
3SAPF_NAJAT Cytotoxin I-like P-15 (Cardiotoxin I-like P-15) Naja atra (Chinese cobra)
3SATF_NAJAT Cytotoxin I-like T-15 (Cardiotoxin I-like T-15) Naja atra (Chinese cobra)
3SAT_NAJAT Cytotoxin 5 (Cardiotoxin A4b) (CTX-A4b) ... Naja atra (Chinese cobra)

1 entry

Venom Kunitz-type family

"Venom Kunitz-type family" VenomZone page
VKT_NAJAT Kunitz-type serine protease inhibitor NACI (Naja ... Naja atra (Chinese cobra)

6 entries

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIa sub-subfamily

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VM3AH_NAJAT Zinc metalloproteinase atrahagin (EC 3.4.24.-) ... Naja atra (Chinese cobra)
VM3A_NAJAT Zinc metalloproteinase-disintegrin-like atrase-A ... Naja atra (Chinese cobra)
VM3B_NAJAT Zinc metalloproteinase-disintegrin-like atrase-B ... Naja atra (Chinese cobra)
VM3H_NAJAT Zinc metalloproteinase-disintegrin-like atragin ... Naja atra (Chinese cobra)
VM3KL_NAJAT Zinc metalloproteinase-disintegrin-like ... Naja atra (Chinese cobra)
VM3_NAJAT Zinc metalloproteinase-disintegrin-like NaMP (EC ... Naja atra (Chinese cobra)