Naja atra (Chinese cobra) (taxid:8656)

Venom composition

Figure 1: Composition of N. atra venom, studied at the transcriptomic level. This venom contains the following families: 3FT (snake three-finger toxin), NGF (NGF-beta), LAAO (flavin monoamine oxidase (L-amino-acid oxidase) ), ohanin/vespryn, CRISP, lectin (true venom lectin), kunitz (venom Kunitz-type), PA2 (phospholipase A2), cystatin, metalloproteinase (venom metalloproteinase) (Jiang et al., 2011).
Cathelicidin, natriuretic peptide, and peptidase S1 (serine protease) have not been observed in this study, but these proteins have been described in this venom (Zhao et al., 2008, Zhan et al., 2011, and Jin et al., 2007).

Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website (Postsynaptic neurotoxins).

Lethal dose LD(50) is 0.29 mg/kg when subcutaneously injected (Jiang et al., 2011).

Venom protein entries in UniProtKB/Swiss-Prot

(all links/actions below point to uniprot.org website)

66 entries grouped by family

reorder by species

1 entry

5'-nucleotidase family

1 entry

Cathelicidin family

2 entries

CRISP family

"CRISP family" VenomZone page

CRVP1_NAJAT Cysteine-rich venom protein natrin-1 ... Naja atra (Chinese cobra)

pdb 1XTA; 1XX5; 2GIZ; 3MZ8

CRVP2_NAJAT Cysteine-rich venom protein natrin-2 ... Naja atra (Chinese cobra)

1 entry

Cystatin family

1 entry

Flavin monoamine oxidase family, FIG1 subfamily

1 entry

Natriuretic peptide family

1 entry

NGF-beta family

1 entry

Nucleotide pyrophosphatase/phosphodiesterase family

"Nucleotide pyrophosphatase/phosphodiesterase family" VenomZone page

PDE_NAJAT Venom phosphodiesterase (PDE) (EC 3.6.1.-) Naja atra (Chinese cobra)

pdb 5GZ4; 5GZ5; 7CBA

1 entry

Peptidase S1 family, Snake venom subfamily

3 entries

Phospholipase A2 family, Group I subfamily, D49 sub-subfamily

"Phospholipase A2 family" VenomZone page

PA2A1_NAJAT Acidic phospholipase A2 1 (svPLA2) (EC 3.1.1.4) ... Naja atra (Chinese cobra)

pdb 1POA; 1POB

PA2A2_NAJAT Acidic phospholipase A2 2 (svPLA2) (EC 3.1.1.4) ... Naja atra (Chinese cobra)

PA2A_NAJAT Acidic phospholipase A2 natratoxin (svPLA2) (EC ... Naja atra (Chinese cobra)

pdb 2OSH

5 entries

Snake three-finger toxin family, Ancestral subfamily, Orphan group II sub-subfamily

"Snake three-finger toxin family" VenomZone page

3NO21_NAJAT Probable weak neurotoxin NNAM1 Naja atra (Chinese cobra)

3NO22_NAJAT Probable weak neurotoxin NNAM2 (TA-N9) Naja atra (Chinese cobra)

3NO23_NAJAT Probable weak neurotoxin NNAM3 Naja atra (Chinese cobra)

3NO2H_NAJAT Long neurotoxin homolog (Kappa-cobrotoxin) Naja atra (Chinese cobra)

3NO2I_NAJAT Probable weak neurotoxin NNAM2I Naja atra (Chinese cobra)

1 entry

Snake three-finger toxin family, Short-chain subfamily, Orphan group I sub-subfamily

1 entry

Snake three-finger toxin family, Short-chain subfamily, Orphan group VIII (haditoxin) sub-subfamily

9 entries

Snake three-finger toxin family, Short-chain subfamily, Orphan group XV sub-subfamily

"Snake three-finger toxin family" VenomZone page

3SOF1_NAJAT Mu-elapitoxin-Na1a (Mu-EPTX-Na1a) Naja atra (Chinese cobra)

3SOF3_NAJAT Cytotoxin homolog Clbp-3 (Cardiotoxin-like basic ... Naja atra (Chinese cobra)

3SOF5_NAJAT Cytotoxin A5 (CTX A5) (CT A5) (Cardiotoxin A5) ... Naja atra (Chinese cobra)

pdb 1CVO; 1KXI

3SOF7_NAJAT Cytotoxin 7 (Cardiotoxin-7) (CTX7) (Ctx-7) ... Naja atra (Chinese cobra)

3SOFA_NAJAT Cardiotoxin 7a Naja atra (Chinese cobra)

3SOFH_NAJAT Cardiotoxin-like basic polypeptide ah (CLBPah) Naja atra (Chinese cobra)

3SOFL_NAJAT Cytotoxin homolog 5 (Cardiotoxin V-like) Naja atra (Chinese cobra)

3SOFP_NAJAT Cardiotoxin 7'' (Cardiotoxin 7') (Cardiotoxin ... Naja atra (Chinese cobra)

3SOFV_NAJAT Cytotoxin homolog 5V (Cardiotoxin-5V) (CTX5V) Naja atra (Chinese cobra)

3 entries

Snake three-finger toxin family, Short-chain subfamily, Type I alpha-neurotoxin sub-subfamily

"Snake three-finger toxin family" VenomZone page

3S11A_NAJAT Alpha-elapitoxin-Na1a (Alpha-EPTX-Na1a) ... Naja atra (Chinese cobra)

3S1CB_NAJAT Cobrotoxin (CBT) (CBTX) (CTX) (Atratoxin) ... Naja atra (Chinese cobra)

pdb 1COE; 1V6P

3S1CC_NAJAT Cobrotoxin-b (CBT-b) (Atratoxin-b) (Cobrotoxin ... Naja atra (Chinese cobra)

pdb 1ONJ; 1VB0

27 entries

Snake three-finger toxin family, Short-chain subfamily, Type IA cytotoxin sub-subfamily

"Snake three-finger toxin family" VenomZone page

3SA1A_NAJAT Cytotoxin 1a (Cardiotoxin-1a) Naja atra (Chinese cobra)

3SA1B_NAJAT Cytotoxin 1b (Cardiotoxin-1b) Naja atra (Chinese cobra)

3SA1C_NAJAT Cytotoxin 1c (Cardiotoxin-1c) Naja atra (Chinese cobra)

3SA1D_NAJAT Cytotoxin 1d/1e (Cardiotoxin-1d/1e) Naja atra (Chinese cobra)

3SA1F_NAJAT Cytotoxin 1f (Cardiotoxin 1f) Naja atra (Chinese cobra)

3SA1_NAJAT Cytotoxin 1 (CX1) (Cardiotoxin 1) (CTX-1) (CTX1) ... Naja atra (Chinese cobra)

pdb 2CDX

3SA2_NAJAT Cytotoxin 2 (Cardiotoxin 1A) (Cardiotoxin 2) ... Naja atra (Chinese cobra)

pdb 1CRE; 1CRF; 4OM4

3SA3A_NAJAT Cytotoxin 3a (Cardiotoxin-31) (Ctx-31) ... Naja atra (Chinese cobra)

3SA3B_NAJAT Cytotoxin 3b (Cardiotoxin 3b) Naja atra (Chinese cobra)

3SA3D_NAJAT Cytotoxin 3d (Cardiotoxin 3d) Naja atra (Chinese cobra)

3SA3_NAJAT Cytotoxin 3 (Cardiotoxin 3) (CTX-3) (CTX3) ... Naja atra (Chinese cobra)

pdb 1H0J; 1I02; 1XT3; 2BHI; 2CRS; 2CRT

3SA4N_NAJAT Cytotoxin 4N (Cardiotoxin-4N) (CTX-4N) Naja atra (Chinese cobra)

3SA4_NAJAT Cytotoxin 4 (CTX-4M) (CTX4) (Cardiotoxin A4) ... Naja atra (Chinese cobra)

pdb 1KBS; 1KBT; 4OM5

3SA5_NAJAT Cytotoxin 5 (Cardiotoxin 5) (CTX5) Naja atra (Chinese cobra)

3SA6_NAJAT Cytotoxin 6 (Cardiotoxin-6) (CTX6) Naja atra (Chinese cobra)

3SA8A_NAJAT Cytotoxin 8 (Cardiotoxin-8) (CTX8) Naja atra (Chinese cobra)

3SA8B_NAJAT Cytotoxin 8 (Cardiotoxin VIII) (Cardiotoxin-8) ... Naja atra (Chinese cobra)

3SAA_NAJAT Cytotoxin 10 (Cardiotoxin-10) (CTX10) (Ctx-10) Naja atra (Chinese cobra)

3SADB_NAJAT Cytotoxin SP13b Naja atra (Chinese cobra)

3SAFA_NAJAT Cytotoxin SP15a Naja atra (Chinese cobra)

3SAFC_NAJAT Cytotoxin SP15c Naja atra (Chinese cobra)

3SAFD_NAJAT Cytotoxin SP15d Naja atra (Chinese cobra)

3SAG_NAJAT Cytotoxin najalgesin Naja atra (Chinese cobra)

3SAN_NAJAT Cytotoxin 6 (Cardiotoxin 6) (CTX6) (Cardiotoxin ... Naja atra (Chinese cobra)

pdb 1UG4

3SAPF_NAJAT Cytotoxin I-like P-15 (Cardiotoxin I-like P-15) Naja atra (Chinese cobra)

3SATF_NAJAT Cytotoxin I-like T-15 (Cardiotoxin I-like T-15) Naja atra (Chinese cobra)

3SAT_NAJAT Cytotoxin 5 (Cardiotoxin A4b) (CTX-A4b) ... Naja atra (Chinese cobra)

pdb 1CHV

1 entry

Venom Kunitz-type family

6 entries

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIa sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page

VM3AH_NAJAT Zinc metalloproteinase atrahagin (EC 3.4.24.-) ... Naja atra (Chinese cobra)

VM3A_NAJAT Zinc metalloproteinase-disintegrin-like atrase-A ... Naja atra (Chinese cobra)

VM3B_NAJAT Zinc metalloproteinase-disintegrin-like atrase-B ... Naja atra (Chinese cobra)

VM3H_NAJAT Zinc metalloproteinase-disintegrin-like atragin ... Naja atra (Chinese cobra)

pdb 3K7L

VM3KL_NAJAT Zinc metalloproteinase-disintegrin-like ... Naja atra (Chinese cobra)

pdb 3K7N

VM3_NAJAT Zinc metalloproteinase-disintegrin-like NaMP (EC ... Naja atra (Chinese cobra)

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Infraorder:	Serpentes

Family:	Elapidae
Genus:	Naja
Species:	atra