Agkistrodon piscivorus piscivorus (Eastern cottonmouth)

Venom composition
Figure 1: Composition of A.p.piscivorus venom, studied at proteomic level (Lomonte, et al., 2014 ). This venom contains the following families: SVMP (venom metalloproteinase ), serine protease (peptidase S1 ), peptides (include tripeptide SVMP inhibitors and bradykinin-potentiating and bradykinin-inhibitory peptides), LAAO (L-amino-acid oxidase (flavin monoamine oxidase) ), disintegrin, snaclec (also known as C-type lectin-like), CRISP, PA2 (phospholipase A2 ).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website
and the WHO venomous snake database to access snake distribution and antivenom products.
Lethal dose LD(50) of A.piscivorus is
6.24 mg/kg by intraperitoneal injection and
5.13 mg/kg by intravenous injection (Arce et al., 2003 ).

Venom protein entries in UniProtKB/Swiss-Prot

10 entries grouped by family (browse by taxonomy, browse by keywords)

1 entry

Bradykinin-potentiating peptide family

"Bradykinin-potentiating peptide family" VenomZone page
BPPF_AGKPI Bradykinin-potentiating peptide F (AppF) (BPP-F) Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

CRISP family

"CRISP family" VenomZone page
CRVP_AGKPI Cysteine-rich venom protein piscivorin Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

Disintegrin family, Dimeric disintegrin subfamily

"Disintegrin family" VenomZone page
DIDA_AGKPI Disintegrin piscivostatin-alpha (PVS-alpha) Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

PDGF/VEGF growth factor family

"PDGF/VEGF growth factor family" VenomZone page
VEGFA_AGKPI Vascular endothelial growth factor A Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

PDGF/VEGF growth factor family, Snake venom VEGF subfamily

"PDGF/VEGF growth factor family" VenomZone page
TXVE_AGKPI Snake venom vascular endothelial growth factor ... Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

Phospholipase A2 family, Group II subfamily, D49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2B1_AGKPI Basic phospholipase A2 APP-D49 (svPLA2) (EC ... Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

Phospholipase A2 family, Group II subfamily, K49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2HB_AGKPI Basic phospholipase A2 homolog (svPLA2 homolog) ... Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

True venom lectin family

"True venom lectin family" VenomZone page
LECG_AGKPI C-type lectin APL (CTL) Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIa sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM2_AGKPI Disintegrin applaggin (Applagin) (Platelet ... Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIe sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM2PB_AGKPI Zinc metalloproteinase/disintegrin [Cleaved ... Agkistrodon piscivorus piscivorus (Eastern ...