Agkistrodon piscivorus piscivorus (Eastern cottonmouth) (taxid:8716)

Venom composition image
Figure 1: Composition of A.p.piscivorus venom, studied at proteomic level (Lomonte, et al., 2014). This venom contains the following families: SVMP (venom metalloproteinase), serine protease (peptidase S1), peptides (include tripeptide SVMP inhibitors and bradykinin-potentiating and bradykinin-inhibitory peptides), LAAO (L-amino-acid oxidase (flavin monoamine oxidase) ), disintegrin, snaclec (also known as C-type lectin-like), CRISP, PA2 (phospholipase A2).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website.
Lethal dose LD(50) of A.piscivorus is
6.24 mg/kg by intraperitoneal injection and
5.13 mg/kg by intravenous injection (Arce et al., 2003).

Venom protein entries in UniProtKB/Swiss-Prot

(all links/actions below point to uniprot.org website)

10 entries grouped by family

1 entry

Bradykinin-potentiating peptide family

"Bradykinin-potentiating peptide family" VenomZone page
BPPF_AGKPI Bradykinin-potentiating peptide F (AppF) (BPP-F) Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

CRISP family

"CRISP family" VenomZone page
CRVP_AGKPI Cysteine-rich venom protein piscivorin Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

Disintegrin family, Dimeric disintegrin subfamily

"Disintegrin family" VenomZone page
DIDA_AGKPI Disintegrin piscivostatin-alpha (PVS-alpha) Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

PDGF/VEGF growth factor family

"PDGF/VEGF growth factor family" VenomZone page
VEGFA_AGKPI Vascular endothelial growth factor A (VEGF-A) Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

PDGF/VEGF growth factor family, Snake venom VEGF subfamily

"PDGF/VEGF growth factor family" VenomZone page
TXVE_AGKPI Snake venom vascular endothelial growth factor ... Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

Phospholipase A2 family, Group II subfamily, D49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2B1_AGKPI Basic phospholipase A2 APP-D49 (svPLA2) (EC ... Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

Phospholipase A2 family, Group II subfamily, K49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2HB_AGKPI Basic phospholipase A2 homolog AppP2 (svPLA2 ... Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

True venom lectin family

"True venom lectin family" VenomZone page
LECG_AGKPI C-type lectin APL (CTL) Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIa sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM2_AGKPI Disintegrin applaggin (Applagin) (Platelet ... Agkistrodon piscivorus piscivorus (Eastern ...

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIe sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM2PB_AGKPI Zinc metalloproteinase/disintegrin [Cleaved ... Agkistrodon piscivorus piscivorus (Eastern ...