Agkistrodon contortrix contortrix ~ VenomZone

Venom composition

Figure 1: Composition of contortrix contortrix venom, studied at proteomic level (Lomonte, et al., 2014).

This venom contains the following families: SVMP (venom metalloproteinase), serine protease (peptidase S1), peptides (include tripeptide SVMP inhibitors and bradykinin-potentiating and bradykinin-inhibitory peptides), LAAO (L-amino-acid oxidase (flavin monoamine oxidase) ), disintegrin, snaclec (also known as C-type lectin-like), NGF (-beta) , CRISP, oha (ohanin/vespryn), DC-fragments (disintegrin/cysteine-rich fragment from P-III SVMPs) and PA2 (phospholipase A2).

Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website.

Lethal dose LD(50) of A.contortrix is
9.17 mg/kg by intraperitoneal injection and
10.17 mg/kg by intravenous injection (Arce et al., 2003).

Venom protein entries in UniProtKB/Swiss-Prot

(all links/actions below point to uniprot.org website)

7 entries grouped by family

1 entry

1 entry

2 entries

"Peptidase S1 family" VenomZone page

VSP2_AGKCO Thrombin-like enzyme contortrixobin (SVTLE) (EC ... Agkistrodon contortrix contortrix (Southern ...

VSPCA_AGKCO Protein C activator (EC 3.4.21.-) (ACC-C) (Snake ... Agkistrodon contortrix contortrix (Southern ...

1 entry

1 entry

1 entry

"Venom metalloproteinase (M12B) family" VenomZone page

VM2AB_AGKCO Zinc metalloproteinase/disintegrin [Cleaved ... Agkistrodon contortrix contortrix (Southern ...

Agkistrodon contortrix contortrix (southern copperhead) (taxid:8713)