Terebra subulata (Photo courtesy of Juliette Gorson). Hastula hectica (Photo courtesy of Yves Terryn).
Use of photos governed by creative commons noncommercial license.
The table below shows the cysteine frameworks (using the Conus nomenclature) that are found in this family of gastropods.
Cysteine framework
number of Cys
Cys pattern
UniProtKB entries or reference
I
4
CC-C-C
α2/8 (CCxxCxxxxxxxxC
α4/4 (CCxxCxxxxxxxxC
α4/5 (CCxxCxxxxxxxxC
VI/VII
6
C-C-CC-C-C
VIII
10
C-C-C-C-C-C-C-C-C-C
IX
6
C-C-C-C-C-C
XI
8
C-C-CC-CC-C-C
XIII
8
C-C-C-CC-C-C-C
XIV
4
C-C-C-C
XV
8
C-C-CC-C-C-C-C
XVI
4
C-C-CC
XVII
8
C-C-CC-C-CC-C
XXII
8
C-C-C-C-C-C-C-C
Novel-8-cys
8
C-C-C-C-C-CCC
Novel-10-cys
10
C-CC-C-C-C-C-C-C-C
Novel-12-cys
12
C-CC-CC-C-C-C-C-C-C-C
The table below shows the classification of teretoxins based on similarities in precursor signal peptide sequences.
Protein family or Superfamily in UniProtKB
UniProtKB entries or reference
Teretoxin A (TA) superfamily
Teretoxin B (TB) superfamily
Teretoxin C (TC) superfamily
Teretoxin D (TD) superfamily
Teretoxin E (TE) superfamily
Teretoxin F (TF) superfamily
Teretoxin G (TG) superfamily
Teretoxin H (TH) superfamily
Teretoxin I (TI) superfamily
Teretoxin J (TJ) superfamily
Teretoxin K (TK) superfamily
Teretoxin L (TL) superfamily
Teretoxin M (TM ) superfamily
Teretoxin N (TN) superfamily
Vasopressin/oxytocin family
Porin family
Venom protein entries in UniProtKB/Swiss-Prot
(all links/actions below point to uniprot.org website)