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Echis ocellatus
(Ocellated saw-scaled viper)
(taxid:99586)
Venom composition
Figure 1: Composition of E. ocellatus venom, studied at both proteomic (A) and transcriptomic (B) levels (
Wagstaff et al., 2009
). Families tagged as "venom" are only detected by proteomic analysis, whereas families tagged as "transcr." are only detected by transcriptomic analysis. Concerning disintegrin and SVMP PII, it is probable that most disintegrins are encoded by SVMP PII and are thus only detected by venomic analysis, whereas SVMP PII are only detected by transcriptomic analysis. Hovewer, it is noteworthy that
Juarez and colleague (2006)
have described disintegrins encoded by disintegrin genes (and not only encoded by SVMP genes). PA2 (
phospholipase A2
),
CRISP
, serine protease (
peptidase S1
),
snaclec (C-type lectin-like)
, LAAO (
L-amino-acid oxidase also known as flavin monoamine oxidase family
),
disintegrin
, DC-fragments (disintegrin/cysteine-rich fragment from PIII SVMPs), SVMP (
snake venom metalloproteinase
), SVMP inhibitor, aspartic proteinase, hyaluronidase (
glycosyl hydrolase 56
) and
PDGF/VEGF growth factor
.
Clinical Effects, Treatment, Antivenoms
See the
Clinical Toxinology Resources Website
.
Lethal dose
LD(50) is 1.005 mg/kg by intravenous injection into mice (
Laing et al., 1995
).
Taxonomy
UniProt taxonomy
The Reptile database
Wikipedia
Infraorder
:
Serpentes
Family
:
Viperidae
Genus:
Echis
Species
:
ocellatus
Activity
see
UniProtKB browsing by keyword
Reference
principal reference:
Wagstaff et al., 2009
other reference:
Wagstaff and Harrison, 2006
Venom protein entries in UniProtKB/Swiss-Prot
(all links/actions below point to
uniprot.org
website)
24 entries
grouped
by species
reorder by family
24 entries
Echis ocellatus (Ocellated saw-scaled viper)
DID1_ECHOC
Disintegrin Eo1 subunit 1 (Eo1-1)
Disintegrin family, Dimeric
...
DID4A_ECHOC
Disintegrin EO4A (Dim-3 SP6) (Eo-10) (Eo-10c1)
Disintegrin family, Dimeric
...
DID5A_ECHOC
Disintegrin EO5A (Eo-12)
Disintegrin family, Dimeric
...
DID5B_ECHOC
Disintegrin EO5B (EO4B)
Disintegrin family, Dimeric
...
DIS_ECHOC
Disintegrin ocellatusin (Short ocellatusion precursor Eo10c-10)
Disintegrin family, Short
...
HYAL_ECHOC
Hyaluronidase (Hy) (EC 3.2.1.35) (Hyaluronoglucosaminidase)
...
Glycosyl hydrolase 56 family
NGFV_ECHOC
Venom nerve growth factor (v-NGF) (vNGF)
NGF-beta family
OXLA_ECHOC
L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2)
Flavin monoamine oxidase family,
...
PA2A5_ECHOC
Acidic phospholipase A2 5 (svPLA2) (EC 3.1.1.4) (PLA2-Eoc79)
...
Phospholipase A2 family, Group
...
PA2HS_ECHOC
Phospholipase A2 homolog (svPLA2 homolog) (PLA2-Eoc15)
Phospholipase A2 family, Group
...
RE123_ECHOC
Renin (EC 3.4.23.15) (Angiotensinogenase) (Renin-like aspartic
...
Peptidase A1 family
RE51_ECHOC
Renin (EC 3.4.23.15) (Angiotensinogenase) (Renin-like aspartic
...
Peptidase A1 family
SL124_ECHOC
Snaclec CTL-Eoc124 (C-type lectin-like CTL-Eoc124)
Snaclec family
SL125_ECHOC
Snaclec CTL-Eoc125 (C-type lectin-like CTL-Eoc125)
Snaclec family
SL1_ECHOC
Snaclec 1 (C-type lectin 1) (CTL-1)
Snaclec family
SL27_ECHOC
Snaclec 27 (C-type lectin 27) (CTL-27)
Snaclec family
SL2_ECHOC
Snaclec 2 (C-type lectin 2) (CTL-2)
Snaclec family
SVMI_ECHOC
Snake venom metalloprotease inhibitor 02D01 (02E11) (10F07)
...
Natriuretic peptide family; PHpG
...
VM2OC_ECHOC
Zinc metalloproteinase/disintegrin (Long ocellatusin precursor
...
Venom metalloproteinase (M12B)
...
VM2OI_ECHOC
Disintegrin ocellatin
Venom metalloproteinase (M12B)
...
VM3E1_ECHOC
Zinc metalloproteinase-disintegrin-like Eoc1 (EC 3.4.24.-)
...
Venom metalloproteinase (M12B)
...
VM3E2_ECHOC
Zinc metalloproteinase-disintegrin-like EoVMP2 (EC 3.4.24.-)
...
Venom metalloproteinase (M12B)
...
VM3E6_ECHOC
Zinc metalloproteinase-disintegrin-like EoMP06 (EC 3.4.24.-)
...
Venom metalloproteinase (M12B)
...
VSP_ECHOC
Serine protease sp-Eoc49 (EC 3.4.21.-) (Snake venom serine
...
Peptidase S1 family, Snake venom
...
