Bothrops atrox (barba amarilla)

Venom composition
Figure 1: Composition of B.atrox venom, studied at both proteomic (A) (Kohlhoffa, et al., 2012 ) and transcriptomic levels (B) (Neiva et al., 2009 ). Disintegrins have been detected by proteomic analysis but not by transcriptomic analysis, suggesting that they are encoded by the SVMP family. VEGF (PDGF/VEGF growth factor ), PA2 inhibitor and BPP precursor (bradykinin-potentiating peptide ) have only been detected by transcriptomic analysis, whereas all other families have been detected by both proteomic and transcriptomic analysis. CRISP, PA2 (phospholipase A2 ), serine protease, C-type lectin (true venom lectin ), LAAO (L-amino-acid oxidase also known as flavin monoamine oxidase ), SVMP (snake venom metalloproteinase ).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website
and the WHO venomous snake database to access snake distribution and antivenom products.
Lethal dose LD(50) is 5.89 mg/kg by intraperitoneal injection into mice
(117.8 (103.7-137.3) ug/mice) (Kohlhoff et al., 2012 ).

Venom protein entries in UniProtKB/Swiss-Prot

13 entries grouped by family (browse by taxonomy, browse by keywords)

1 entry

Bradykinin-potentiating peptide family

"Bradykinin-potentiating peptide family" VenomZone page
BPP12_BOTAT Bradykinin-potentiating peptide 12a (BPP-12a) ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

1 entry

Cathelicidin family

"Cathelicidin family" VenomZone page
CAMP_BOTAT Cathelicidin-related peptide batroxicidin ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

1 entry

Flavin monoamine oxidase family, FIG1 subfamily

"Flavin monoamine oxidase family" VenomZone page
OXLA_BOTAT L-amino-acid oxidase (BatroxLAAO) (LAO) (EC ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

1 entry

Not in a family

VPA_BOTAT Venom prothrombin activator (vPA) (Fragment) Bothrops atrox (Barba amarilla) (Fer-de-lance)

1 entry

Peptidase S1 family, Snake venom subfamily

"Peptidase S1 family" VenomZone page
VSPF_BOTAT Thrombin-like enzyme batroxobin (BX) (SVTLE) (EC ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

1 entry

Phospholipase A2 family, Group II subfamily, K49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2H1_BOTAT Phospholipase A2 homolog 1 (svPLA2 homolog) ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

1 entry

True venom lectin family

"True venom lectin family" VenomZone page
LECG_BOTAT C-type lectin galatrox (CTL) (Fragments) Bothrops atrox (Barba amarilla) (Fer-de-lance)

2 entries

Venom metalloproteinase (M12B) family, P-I subfamily

Select_allDeselect_all "Venom metalloproteinase (M12B) family" VenomZone page
VM11_BOTAT Snake venom metalloproteinase atroxlysin-1 ... Bothrops atrox (Barba amarilla) (Fer-de-lance)
VM1B1_BOTAT Snake venom metalloproteinase Batx-1 (SVMP) (EC ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

1 entry

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIa sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM2_BOTAT Disintegrin batroxostatin (Disintegrin ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

2 entries

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIa sub-subfamily

Select_allDeselect_all "Venom metalloproteinase (M12B) family" VenomZone page
VM31_BOTAT Zinc metalloproteinase-disintegrin-like ... Bothrops atrox (Barba amarilla) (Fer-de-lance)
VM33_BOTAT Zinc metalloproteinase-disintegrin-like ... Bothrops atrox (Barba amarilla) (Fer-de-lance)

1 entry

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIc sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM32_BOTAT Zinc metalloproteinase-disintegrin-like ... Bothrops atrox (Barba amarilla) (Fer-de-lance)