Echis ocellatus (Ocellated saw-scaled viper)

Venom composition
Figure 1: Composition of E. ocellatus venom, studied at both proteomic (A) and transcriptomic (B) levels (Wagstaff et al., 2009 ). Families tagged as “venom” are only detected by proteomic analysis, whereas families tagged as “transcr.” are only detected by transcriptomic analysis. Concerning disintegrin and SVMP PII, it is probable that most disintegrins are encoded by SVMP PII and are thus only detected by venomic analysis, whereas SVMP PII are only detected by transcriptomic analysis. Hovewer, it is noteworthy that Juarez and colleague (2006) have described disintegrins encoded by disintegrin genes (and not only encoded by SVMP genes). PA2 (phospholipase A2 ), CRISP, serine protease (peptidase S1 ), snaclec (C-type lectin-like) , LAAO (L-amino-acid oxidase also known as flavin monoamine oxidase family ), disintegrin, DC-fragments (disintegrin/cysteine-rich fragment from PIII SVMPs), SVMP (snake venom metalloproteinase ), SVMP inhibitor, aspartic proteinase, hyaluronidase (glycosyl hydrolase 56 ) and PDGF/VEGF growth factor.
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website
and the WHO venomous snake database to access snake distribution and antivenom products.
Lethal dose LD(50) is 1.005 mg/kg by intravenous injection into mice (Laing et al., 1995 ).

Venom protein entries in UniProtKB/Swiss-Prot

22 entries grouped by family (browse by taxonomy, browse by keywords)

4 entries

Disintegrin family, Dimeric disintegrin subfamily

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DID1_ECHOC Disintegrin Eo1 subunit 1 (Eo1-1) Echis ocellatus (Ocellated saw-scaled viper)
DID4A_ECHOC Disintegrin EO4A (Dim-3 SP6) (Eo-10) (Eo-10c1) Echis ocellatus (Ocellated saw-scaled viper)
DID5A_ECHOC Disintegrin EO5A (Eo-12) Echis ocellatus (Ocellated saw-scaled viper)
DID5B_ECHOC Disintegrin EO5B (EO4B) Echis ocellatus (Ocellated saw-scaled viper)

1 entry

Disintegrin family, Short disintegrin subfamily

"Disintegrin family" VenomZone page
DIS_ECHOC Disintegrin ocellatusin (Short ocellatusion ... Echis ocellatus (Ocellated saw-scaled viper)

1 entry

Flavin monoamine oxidase family, FIG1 subfamily

"Flavin monoamine oxidase family" VenomZone page
OXLA_ECHOC L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2) Echis ocellatus (Ocellated saw-scaled viper)

1 entry

Glycosyl hydrolase 56 family

"Glycosyl hydrolase 56 family" VenomZone page
HYAL_ECHOC Hyaluronidase (Hy) (EC 3.2.1.35) ... Echis ocellatus (Ocellated saw-scaled viper)

1 entry

Natriuretic peptide family; PHpG family

"Natriuretic peptide family" VenomZone page
SVMI_ECHOC Snake venom metalloprotease inhibitor 02D01 ... Echis ocellatus (Ocellated saw-scaled viper)

1 entry

NGF-beta family

"NGF-beta family" VenomZone page
NGFV_ECHOC Venom nerve growth factor (v-NGF) (vNGF) ... Echis ocellatus (Ocellated saw-scaled viper)

1 entry

Peptidase S1 family, Snake venom subfamily

"Peptidase S1 family" VenomZone page
VSP_ECHOC Serine protease sp-Eoc49 (EC 3.4.21.-) (Snake ... Echis ocellatus (Ocellated saw-scaled viper)

1 entry

Phospholipase A2 family, Group II subfamily, D49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2A5_ECHOC Acidic phospholipase A2 5 (svPLA2) (EC 3.1.1.4) ... Echis ocellatus (Ocellated saw-scaled viper)

1 entry

Phospholipase A2 family, Group II subfamily, S49 sub-subfamily

"Phospholipase A2 family" VenomZone page
PA2HS_ECHOC Phospholipase A2 homolog (svPLA2 homolog) ... Echis ocellatus (Ocellated saw-scaled viper)

5 entries

Snaclec family

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SL124_ECHOC Snaclec CTL-Eoc124 (C-type lectin-like ... Echis ocellatus (Ocellated saw-scaled viper)
SL125_ECHOC Snaclec CTL-Eoc125 (C-type lectin-like ... Echis ocellatus (Ocellated saw-scaled viper)
SL1_ECHOC Snaclec 1 (C-type lectin 1) (CTL-1) Echis ocellatus (Ocellated saw-scaled viper)
SL27_ECHOC Snaclec 27 (C-type lectin 27) (CTL-27) ... Echis ocellatus (Ocellated saw-scaled viper)
SL2_ECHOC Snaclec 2 (C-type lectin 2) (CTL-2) Echis ocellatus (Ocellated saw-scaled viper)

2 entries

Venom metalloproteinase (M12B) family, P-II subfamily, P-IIa sub-subfamily

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VM2OC_ECHOC Zinc metalloproteinase/disintegrin (Long ... Echis ocellatus (Ocellated saw-scaled viper)
VM2OI_ECHOC Disintegrin ocellatin Echis ocellatus (Ocellated saw-scaled viper)

2 entries

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIa sub-subfamily

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VM3E2_ECHOC Zinc metalloproteinase-disintegrin-like EoVMP2 ... Echis ocellatus (Ocellated saw-scaled viper)
VM3E6_ECHOC Zinc metalloproteinase-disintegrin-like EoMP06 ... Echis ocellatus (Ocellated saw-scaled viper)

1 entry

Venom metalloproteinase (M12B) family, P-III subfamily, P-IIIc sub-subfamily

"Venom metalloproteinase (M12B) family" VenomZone page
VM3E1_ECHOC Zinc metalloproteinase-disintegrin-like Eoc1 (EC ... Echis ocellatus (Ocellated saw-scaled viper)