Mesobuthus martensii (Chinese scorpion) (taxid:34649)

Venom composition Unfortunately, there is no transcriptomic or proteomic analysis reporting the venom composition of M.martensii yet. However, a first draft of the genome has been submitted. A total of 116 neurotoxin genes have been reported, the prediction can be viewed below. NaTx (sodium channel toxins), KTx (potassium channel toxins), ClTx (chloride channel toxins) and CaTx (ryanodine receptor toxins) (Cao et al., 2013).

Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website.

Lethal dose

Miscellaneous M. martensii is a raw material for traditional Chinese medicine and is used to treat diseases like rheumatoid arthritis, apoplexy, epilepsy and chronic pain (Cao et al., 2013).

Venom protein entries in UniProtKB/Swiss-Prot

(all links/actions below point to uniprot.org website)

114 entries grouped by family

reorder by species

1 entry

Glycosyl hydrolase 56 family

1 entry

Invertebrate defensin family

5 entries

Invertebrate defensin family, Type 2 subfamily

DEF1_MESMA Defensin BmKDfsin1 Mesobuthus martensii (Manchurian scorpion) ...

DEF2_MESMA Defensin BmKDfsin2 Mesobuthus martensii (Manchurian scorpion) ...

DEF3_MESMA Defensin BmKDfsin3 Mesobuthus martensii (Manchurian scorpion) ...

pdb 5XA6

DEF5_MESMA Defensin BmKDfsin5 Mesobuthus martensii (Manchurian scorpion) ...

DEF6_MESMA Defensin BmKDfsin6 Mesobuthus martensii (Manchurian scorpion) ...

2 entries

Long (3 C-C) scorpion toxin superfamily

LV1A_MESMA Lipolysis-activating peptide 1-alpha chain ... Mesobuthus martensii (Manchurian scorpion) ...

LV1B_MESMA HMG-CoA reductase inhibitor bumarsin (JCH2) ... Mesobuthus martensii (Manchurian scorpion) ...

1 entry

Long (3 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Beta subfamily

4 entries

Long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family

SCAS_MESMA Beta-toxin BmKAS (BmK AS) (BmK-AS) (BmK-PL) Mesobuthus martensii (Manchurian scorpion) ...

SCAT_MESMA Beta-toxin BmKAs1 (BmK AS-1) (BmK activator of ... Mesobuthus martensii (Manchurian scorpion) ...

SCX11_MESMA Toxin BmKNJX11 Mesobuthus martensii (Manchurian scorpion) ...

SIXI_MESMA Depressant scorpion toxin BmKIM Mesobuthus martensii (Manchurian scorpion) ...

30 entries

Long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Alpha subfamily

MKTX1_MESMA Makatoxin-1 (Makatoxin I) (MKTXI) (MakatxI) ... Mesobuthus martensii (Manchurian scorpion) ...

MKTX2_MESMA Makatoxin-2 (Makatoxin II) (MKTXII) (MakatxII) ... Mesobuthus martensii (Manchurian scorpion) ...

MKTX3_MESMA Makatoxin-3 (Makatoxin III) (MKTXIII) ... Mesobuthus martensii (Manchurian scorpion) ...

SC10_MESMA Toxin BmKaTx10 (Alpha-neurotoxin Tx10) ... Mesobuthus martensii (Manchurian scorpion) ...

SC11_MESMA BmK AGP-SYPU2 (Alpha-neurotoxin Tx11) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 2KBH; 2KBJ

SC12_MESMA Toxin BmKaIT1 (BmKalphaIT1) (Alpha-neurotoxin ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1OMY; 2E0H

SC13_MESMA Toxin BmKaTx13 (Alpha-neurotoxin Tx13) ... Mesobuthus martensii (Manchurian scorpion) ...

SC15_MESMA Toxin BmKaTX15 (Alpha-neurotoxin Tx15) ... Mesobuthus martensii (Manchurian scorpion) ...

SC16_MESMA Toxin BmKaTx16 (Alpha-neurotoxin Tx16) ... Mesobuthus martensii (Manchurian scorpion) ...

SC17_MESMA Toxin BmKaTx17 (Alpha-neurotoxin Tx17) ... Mesobuthus martensii (Manchurian scorpion) ...

SC18_MESMA Neurotoxin BmK 18(2) Mesobuthus martensii (Manchurian scorpion) ...

SCA1_MESMA Toxin BmKa1 (Alpha-toxin 1) (BmKalpha1) Mesobuthus martensii (Manchurian scorpion) ...

SCA3_MESMA Toxin BmKa3 (Alpha-toxin 3) (BmKalpha3) Mesobuthus martensii (Manchurian scorpion) ...

SCA4_MESMA Alpha-toxin 4 (BmK alpha IV) (BmKalpha4) Mesobuthus martensii (Manchurian scorpion) ...

SCAA2_MESMA Neurotoxin BmK AGAP-SYPU2 Mesobuthus martensii (Manchurian scorpion) ...

SCAA_MESMA Toxin BmKT (BmK T) (Antitumor-analgesic peptide) ... Mesobuthus martensii (Manchurian scorpion) ...

SCBK_MESMA Bukatoxin (BukaTx) (BuK-alpha-Tx) Mesobuthus martensii (Manchurian scorpion) ...

SCM1_MESMA Alpha-like toxin BmK M1 (BmK-M1) (BmKM1) (BmK-I) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1DJT; 1SN1; 1T7A; 1T7B; 1T7E; 1ZU3; 1ZUT; 1ZVE; 1ZVG; 1ZYV; 1ZYW

SCM2_MESMA Alpha-like toxin BmK M2 (BmK-M2) (BmKM2) Mesobuthus martensii (Manchurian scorpion) ...

pdb 1CHZ

SCU1_MESMA Neurotoxin BmK AGP-SYPU1 Mesobuthus martensii (Manchurian scorpion) ...

SCX2_MESMA Neurotoxin BmK-II (BmK II) (BmKII) (BmK2) Mesobuthus martensii (Manchurian scorpion) ...

SCX3_MESMA Neurotoxin BmK-M3 (BmK3) (BmKM3) (Bmk M3) (BmK ... Mesobuthus martensii (Manchurian scorpion) ...

SCX47_MESMA Alpha-toxin BmalphaTx47 Mesobuthus martensii (Manchurian scorpion) ...

SCX4_MESMA Alpha-like toxin BmK-M4 (BmK4) (BmKM4) (Bmk M4) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1SN4

SCX7_MESMA Alpha-like toxin BmK-M7 (BmKM7) (Bmk M7) Mesobuthus martensii (Manchurian scorpion) ...

pdb 1KV0

SCX8_MESMA Alpha-mammal toxin BmK-M8 (BmK8) (Bmk M8) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1SNB

SCX9_MESMA Neurotoxin BmK-M9 (BmK9) (Bmk M9) (BmkM9) ... Mesobuthus martensii (Manchurian scorpion) ...

SCXA_MESMA Neurotoxin BmK-M10 (Alpha-neurotoxin TX9) (BmK ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 2KBK

SCXB_MESMA Neurotoxin BmK-M11 (BmK11) (Bmk M11) (BmkM11) ... Mesobuthus martensii (Manchurian scorpion) ...

SCXT2_MESMA Sodium channel neurotoxin BmK NT2 ... Mesobuthus martensii (Manchurian scorpion) ...

16 entries

Long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Beta subfamily

AEP1_MESMA Toxin BmKAEP (Anti-epilepsy peptide) (BmK AEP) Mesobuthus martensii (Manchurian scorpion) ...

AEP2_MESMA Neurotoxin BmKAEP2 (AEP2) Mesobuthus martensii (Manchurian scorpion) ...

SCBTY_MESMA BmKBT-like peptide (Beta-toxin BmKBy) Mesobuthus martensii (Manchurian scorpion) ...

SCBT_MESMA Toxin BmKBT (BmK BT) (BmKabT) (BmK abT) Mesobuthus martensii (Manchurian scorpion) ...

SCN2_MESMA Anti-neuroexcitation peptide 2 (BmKANEP2) ... Mesobuthus martensii (Manchurian scorpion) ...

SCN3_MESMA Anti-neuroexcitation peptide 3 (BmKANEP3) ... Mesobuthus martensii (Manchurian scorpion) ...

SIX1_MESMA Beta-insect excitatory toxin BmKIT1 (Bm32-VI) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1WWN

SIX2_MESMA Beta-insect depressant toxin BmKIT2 (Depressant ... Mesobuthus martensii (Manchurian scorpion) ...

SIX3_MESMA Toxin BmKIT3 (BmK IT3) (Insect toxin 3) Mesobuthus martensii (Manchurian scorpion) ...

SIX4_MESMA Beta-insect depressant toxin BmKIT4 (BmK IT4) ... Mesobuthus martensii (Manchurian scorpion) ...

SIXA1_MESMA Depressant insect toxin BmK ITa1 Mesobuthus martensii (Manchurian scorpion) ...

SIXA_MESMA Beta-insect depressant toxin BmKITa (BmK ITa) ... Mesobuthus martensii (Manchurian scorpion) ...

SIXB_MESMA Beta-insect depressant toxin BmKITb (BmK ITb) Mesobuthus martensii (Manchurian scorpion) ...

SIXC_MESMA Toxin BmKITc (BmK ITc) Mesobuthus martensii (Manchurian scorpion) ...

SIXP1_MESMA Insect toxin BmK AngP1 Mesobuthus martensii (Manchurian scorpion) ...

SIXP_MESMA Beta-insect excitatory toxin BmK IT-AP (Bm33-I) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1T0Z

1 entry

Long chain scorpion toxin family, Class 1 subfamily

1 entry

Long chain scorpion toxin family, Class 2 subfamily

1 entry

Non-disulfide-bridged peptide (NDBP) superfamily

2 entries

Non-disulfide-bridged peptide (NDBP) superfamily, Long chain multifunctional peptide (group 2) family

NDB22_MESMA Bradykinin-potentiating peptide BmKbpp (Bpp ... Mesobuthus martensii (Manchurian scorpion) ...

NDB2S_MESMA Peptide BmKa2 (Acidic venom peptide Ka2) ... Mesobuthus martensii (Manchurian scorpion) ...

3 entries

Non-disulfide-bridged peptide (NDBP) superfamily, Short antimicrobial peptide (group 4) family

NDB43_MESMA Peptide BmKb1 (Antimicrobial peptide-like ... Mesobuthus martensii (Manchurian scorpion) ...

NDB44_MESMA Peptide BmKn2 (Kn2) (Non-disulfide-bridged ... Mesobuthus martensii (Manchurian scorpion) ...

NDB4U_MESMA Peptide BmKn1 (Biologically active peptide 4) ... Mesobuthus martensii (Manchurian scorpion) ...

7 entries

Not in a family

KS4_MESMA Toxin BmTxKS4 (KS3 toxin) Mesobuthus martensii (Manchurian scorpion) ...

SCK6_MESMA Neurotoxin BmK A3-6 Mesobuthus martensii (Manchurian scorpion) ...

SCKH_MESMA Neurotoxin X-29S Mesobuthus martensii (Manchurian scorpion) ...

SCKI_MESMA Neurotoxin BmP08 (Short-chain peptide BmKX) Mesobuthus martensii (Manchurian scorpion) ...

pdb 1RJI; 1WT8

SCKJ_MESMA Neurotoxin BmKX-A1-S31 Mesobuthus martensii (Manchurian scorpion) ...

SCS1_MESMA Putative potassium channel blocker TXKS1 ... Mesobuthus martensii (Manchurian scorpion) ...

YA_MESMA BmK-YA precursor [Cleaved into: BmK-YA 1 ... Mesobuthus martensii (Manchurian scorpion) ...

1 entry

Peptidase S1 family

1 entry

Scorpion calcin-like family

1 entry

Scorpion La1-like peptide family

1 entry

Serine protease inhibitor-like (TIL domain-containing) family

2 entries

Short scorpion toxin superfamily, Chloride channel inhibitor family

CTXLB_MESMA Chlorotoxin-like peptide Bm12-b Mesobuthus martensii (Manchurian scorpion) ...

CTXL_MESMA Chlorotoxin-like BmK CT (BmKCT) (Bm-12) (BmKCL1) ... Mesobuthus martensii (Manchurian scorpion) ...

5 entries

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 01 subfamily

KAX15_MESMA Potassium channel toxin alpha-KTx 1.5 (BmTX1) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1BIG; 6AVC

KAX16_MESMA Potassium channel toxin alpha-KTx 1.6 (BmTX2) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 2BMT

KAX1E_MESMA Potassium channel toxin alpha-KTx 1.14 (BmKcug1) ... Mesobuthus martensii (Manchurian scorpion) ...

KAX1F_MESMA Potassium channel toxin alpha-KTx 1.15 (BmKcug2) ... Mesobuthus martensii (Manchurian scorpion) ...

KAX1X_MESMA Potassium channel toxin alpha-KTx BmKcug1a ... Mesobuthus martensii (Manchurian scorpion) ...

2 entries

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 03 subfamily

KAX36_MESMA Potassium channel toxin alpha-KTx 3.6 (BmKTX) Mesobuthus martensii (Manchurian scorpion) ...

pdb 1BKT; 2K4U; 2MLA; 2MLD

KAX3V_MESMA Toxin BmK NSPK (Buthus martensii Karsch ... Mesobuthus martensii (Manchurian scorpion) ...

1 entry

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 05 subfamily

1 entry

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 08 subfamily

2 entries

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 09 subfamily

KAX91_MESMA Potassium channel toxin alpha-KTx 9.1 (BmKK6) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1DU9

KAX92_MESMA Potassium channel toxin alpha-KTx 9.2 ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1WM8

1 entry

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 11 subfamily

5 entries

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 14 subfamily

KA141_MESMA Potassium channel toxin alpha-KTx 14.1 (BmKK1) ... Mesobuthus martensii (Manchurian scorpion) ...

KA142_MESMA Potassium channel toxin alpha-KTx 14.2 (BmKK2) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1PVZ

KA143_MESMA Potassium channel toxin alpha-KTx 14.3 (BmKK3) ... Mesobuthus martensii (Manchurian scorpion) ...

KA144_MESMA Potassium channel toxin alpha-KTx 14.4 (BmSKTx1) ... Mesobuthus martensii (Manchurian scorpion) ...

KA14_MESMA Potassium channel toxin alpha-KTx 14.x (BmKK14) Mesobuthus martensii (Manchurian scorpion) ...

2 entries

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 15 subfamily

KA152_MESMA Potassium channel toxin alpha-KTx 15.2 (BmTX3) ... Mesobuthus martensii (Manchurian scorpion) ...

KA158_MESMA Potassium channel toxin alpha-KTx 15.8 (BmKKx1) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 6AY8

2 entries

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 16 subfamily

KA162_MESMA Potassium channel toxin alpha-KTx 16.2 (BmK 622) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1M2S

KA163_MESMA Potassium channel toxin alpha-KTx 16.3 ... Mesobuthus martensii (Manchurian scorpion) ...

3 entries

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 17 subfamily

KA171_MESMA Potassium channel toxin alpha-KTx 17.1 (BmKK4) ... Mesobuthus martensii (Manchurian scorpion) ...

pdb 1S8K

KA17C_MESMA Toxin BmKK12 Mesobuthus martensii (Manchurian scorpion) ...

KA17G_MESMA Toxin BmKK16 Mesobuthus martensii (Manchurian scorpion) ...

1 entry

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 19 subfamily

1 entry

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 22 subfamily

2 entries

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 26 subfamily

KA261_MESMA Potassium channel toxin alpha-KTx 26.1 ... Mesobuthus martensii (Manchurian scorpion) ...

KA26U_MESMA Mesomartoxin (MMTX) Mesobuthus martensii (Manchurian scorpion) ...

pdb 2RTZ

1 entry

Short scorpion toxin superfamily, Potassium channel inhibitor family, Gamma-KTx 2 subfamily

1 entry

Venom Kunitz-type family, Scorpion delta-Ktx subfamily, Delta-Ktx 1 sub-subfamily

1 entry

Venom Kunitz-type family, Scorpion delta-Ktx subfamily, Delta-Ktx 2 sub-subfamily

1 entry

Venom Kunitz-type family, Scorpion delta-Ktx subfamily, Delta-Ktx 3 sub-subfamily

1 entry

Venom metalloproteinase (M12B) family

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Order:	Scorpiones

Family:	Buthidae
Genus:	Mesobuthus
Species:	martensii