Naja atra (Chinese cobra) (taxid:8656)


Venom composition image
Figure 1: Composition of N. atra venom, studied at the transcriptomic level. This venom contains the following families: 3FT (snake three-finger toxin), NGF (NGF-beta), LAAO (flavin monoamine oxidase (L-amino-acid oxidase) ), ohanin/vespryn, CRISP, lectin (true venom lectin), kunitz (venom Kunitz-type), PA2 (phospholipase A2), cystatin, metalloproteinase (venom metalloproteinase) (Jiang et al., 2011).
Cathelicidin, natriuretic peptide, and peptidase S1 (serine protease) have not been observed in this study, but these proteins have been described in this venom (Zhao et al., 2008, Zhan et al., 2011, and Jin et al., 2007).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website (Postsynaptic neurotoxins).
Lethal dose LD(50) is 0.29 mg/kg when subcutaneously injected (Jiang et al., 2011).
Taxonomy

UniProt taxonomy
The Reptile database
Wikipedia

Infraorder: Serpentes


Family: Elapidae
Genus: Naja
Species: atra
Activity Antimicrobial
Cardiotoxin
Complement system impairing toxin
Cell adhesion impairing toxin
Hemostasis impairing toxin
  Blood coagulation cascade inhibiting toxin
  Fibrinogenolytic toxin
  Platelet agg. activating toxin
  Platelet agg. inhibiting toxin
Hypotensive agent
Neurotoxin
  Postsynaptic neurotoxin
Vasodilator
or see
UniProtKB browsing by keyword
Reference Jiang et al., 2011

Venom protein entries in UniProtKB/Swiss-Prot

(all links/actions below point to uniprot.org website)

66 entries grouped by species

66 entries

Naja atra (Chinese cobra)

Select_allDeselect_all
3NO21_NAJAT Probable weak neurotoxin NNAM1 Three-finger toxin family, ...
3NO22_NAJAT Probable weak neurotoxin NNAM2 (TA-N9) Three-finger toxin family, ...
3NO23_NAJAT Probable weak neurotoxin NNAM3 Three-finger toxin family, ...
3NO2H_NAJAT Long neurotoxin homolog (Kappa-cobrotoxin) Three-finger toxin family, ...
3NO2I_NAJAT Probable weak neurotoxin NNAM2I Three-finger toxin family, ...
3S11A_NAJAT Alpha-elapitoxin-Na1a (Alpha-EPTX-Na1a) (Three-finger toxin) Three-finger toxin family, ...
3S1CB_NAJAT Cobrotoxin (CBT) (CBTX) (CTX) (Atratoxin) (Cobratide) (Short ... Three-finger toxin family, ...

pdb 1COE; 1V6P

3S1CC_NAJAT Cobrotoxin-b (CBT-b) (Atratoxin-b) (Cobrotoxin III) (CBT-III) ... Three-finger toxin family, ...

pdb 1ONJ; 1VB0

3SA1A_NAJAT Cytotoxin 1a (Cardiotoxin-1a) Three-finger toxin family, ...
3SA1B_NAJAT Cytotoxin 1b (Cardiotoxin-1b) Three-finger toxin family, ...
3SA1C_NAJAT Cytotoxin 1c (Cardiotoxin-1c) Three-finger toxin family, ...
3SA1D_NAJAT Cytotoxin 1d/1e (Cardiotoxin-1d/1e) Three-finger toxin family, ...
3SA1F_NAJAT Cytotoxin 1f (Cardiotoxin 1f) Three-finger toxin family, ...
3SA1_NAJAT Cytotoxin 1 (CX1) (Cardiotoxin 1) (CTX-1) (CTX1) (Cardiotoxin ... Three-finger toxin family, ...

pdb 2CDX

3SA2_NAJAT Cytotoxin 2 (Cardiotoxin 1A) (Cardiotoxin 2) (CTX-2) ... Three-finger toxin family, ...

pdb 1CRE; 1CRF; 4OM4

3SA3A_NAJAT Cytotoxin 3a (Cardiotoxin-31) (Ctx-31) (Cardiotoxin-3a) Three-finger toxin family, ...
3SA3B_NAJAT Cytotoxin 3b (Cardiotoxin 3b) Three-finger toxin family, ...
3SA3D_NAJAT Cytotoxin 3d (Cardiotoxin 3d) Three-finger toxin family, ...
3SA3_NAJAT Cytotoxin 3 (Cardiotoxin 3) (CTX-3) (CTX3) (Cardiotoxin A3) (CTX ... Three-finger toxin family, ...

pdb 1H0J; 1I02; 1XT3; 2BHI; 2CRS; 2CRT

3SA4N_NAJAT Cytotoxin 4N (Cardiotoxin-4N) (CTX-4N) Three-finger toxin family, ...
3SA4_NAJAT Cytotoxin 4 (CTX-4M) (CTX4) (Cardiotoxin A4) (CTX A4) ... Three-finger toxin family, ...

pdb 1KBS; 1KBT; 4OM5

3SA5_NAJAT Cytotoxin 5 (Cardiotoxin 5) (CTX5) Three-finger toxin family, ...
3SA6_NAJAT Cytotoxin 6 (Cardiotoxin-6) (CTX6) Three-finger toxin family, ...
3SA8A_NAJAT Cytotoxin 8 (Cardiotoxin-8) (CTX8) Three-finger toxin family, ...
3SA8B_NAJAT Cytotoxin 8 (Cardiotoxin VIII) (Cardiotoxin-8) (CTX8) Three-finger toxin family, ...
3SAA_NAJAT Cytotoxin 10 (Cardiotoxin-10) (CTX10) (Ctx-10) Three-finger toxin family, ...
3SADB_NAJAT Cytotoxin SP13b Three-finger toxin family, ...
3SAFA_NAJAT Cytotoxin SP15a Three-finger toxin family, ...
3SAFC_NAJAT Cytotoxin SP15c Three-finger toxin family, ...
3SAFD_NAJAT Cytotoxin SP15d Three-finger toxin family, ...
3SAG_NAJAT Cytotoxin najalgesin Three-finger toxin family, ...
3SAN_NAJAT Cytotoxin 6 (Cardiotoxin 6) (CTX6) (Cardiotoxin A6) (CTX A6) ... Three-finger toxin family, ...

pdb 1UG4

3SAPF_NAJAT Cytotoxin I-like P-15 (Cardiotoxin I-like P-15) Three-finger toxin family, ...
3SATF_NAJAT Cytotoxin I-like T-15 (Cardiotoxin I-like T-15) Three-finger toxin family, ...
3SAT_NAJAT Cytotoxin 5 (Cardiotoxin A4b) (CTX-A4b) (Cardiotoxin T) ... Three-finger toxin family, ...

pdb 1CHV

3SO1_NAJAT Neurotoxin-like protein NTL2 Three-finger toxin family, ...
3SO8_NAJAT Neurotoxin homolog NL1 Three-finger toxin family, ...
3SOF1_NAJAT Mu-elapitoxin-Na1a (Mu-EPTX-Na1a) Three-finger toxin family, ...
3SOF3_NAJAT Cytotoxin homolog Clbp-3 (Cardiotoxin-like basic protein 3) ... Three-finger toxin family, ...
3SOF5_NAJAT Cytotoxin A5 (CTX A5) (CT A5) (Cardiotoxin A5) (Cardiotoxin V) ... Three-finger toxin family, ...

pdb 1CVO; 1KXI

3SOF7_NAJAT Cytotoxin 7 (Cardiotoxin-7) (CTX7) (Ctx-7) (Cardiotoxin-like ... Three-finger toxin family, ...
3SOFA_NAJAT Cardiotoxin 7a Three-finger toxin family, ...
3SOFH_NAJAT Cardiotoxin-like basic polypeptide ah (CLBPah) Three-finger toxin family, ...
3SOFL_NAJAT Cytotoxin homolog 5 (Cardiotoxin V-like) Three-finger toxin family, ...
3SOFP_NAJAT Cardiotoxin 7'' (Cardiotoxin 7') (Cardiotoxin VII) Three-finger toxin family, ...
3SOFV_NAJAT Cytotoxin homolog 5V (Cardiotoxin-5V) (CTX5V) Three-finger toxin family, ...
CAMP_NAJAT Cathelicidin-related antimicrobial peptide Na_CRAMP ... Cathelicidin family
CRVP1_NAJAT Cysteine-rich venom protein natrin-1 (Cysteine-rich venom ... CRISP family

pdb 1XTA; 1XX5; 2GIZ; 3MZ8

CRVP2_NAJAT Cysteine-rich venom protein natrin-2 (Cysteine-rich venom ... CRISP family
CYT_NAJAT Cystatin Cystatin family
NGFV_NAJAT Venom nerve growth factor (v-NGF) (vNGF) (Cobra nerve growth ... NGF-beta family

pdb 4EC7

OXLA_NAJAT L-amino-acid oxidase (LAO) (NA-LAAO) (EC 1.4.3.2) Flavin monoamine oxidase family, ...

pdb 5Z2G

PA2A1_NAJAT Acidic phospholipase A2 1 (svPLA2) (EC 3.1.1.4) (Muscarinic ... Phospholipase A2 family, Group I ...

pdb 1POA; 1POB

PA2A2_NAJAT Acidic phospholipase A2 2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...
PA2A_NAJAT Acidic phospholipase A2 natratoxin (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...

pdb 2OSH

PDE_NAJAT Venom phosphodiesterase (PDE) (EC 3.6.1.-) Nucleotide ...

pdb 5GZ4; 5GZ5; 7CBA

V5NTD_NAJAT Snake venom 5'-nucleotidase (5'-NT) (EC 3.1.3.5) ... 5'-nucleotidase family

pdb 5H7W; 7D0V

VKT_NAJAT Kunitz-type serine protease inhibitor NACI (Naja atra ... Venom Kunitz-type family

pdb 2M99

VM3AH_NAJAT Zinc metalloproteinase atrahagin (EC 3.4.24.-) (Snake venom ... Venom metalloproteinase (M12B) ...
VM3A_NAJAT Zinc metalloproteinase-disintegrin-like atrase-A (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM3B_NAJAT Zinc metalloproteinase-disintegrin-like atrase-B (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VM3H_NAJAT Zinc metalloproteinase-disintegrin-like atragin (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...

pdb 3K7L

VM3KL_NAJAT Zinc metalloproteinase-disintegrin-like kaouthiagin-like ... Venom metalloproteinase (M12B) ...

pdb 3K7N

VM3_NAJAT Zinc metalloproteinase-disintegrin-like NaMP (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VNP_NAJAT Natriuretic peptide Na-NP Natriuretic peptide family
VSP1_NAJAT Snake venom serine protease NaSP (SVSP) (EC 3.4.21.-) Peptidase S1 family, Snake venom ...