Tityus serrulatus (Brazilian scorpion)

Venom composition
Figure 1: Composition of T. serrulatus venom, studied at the proteomic level. This venom contains the following families (classified by activity): sodium channel toxins (NaTx), potassium channel toxins (KTx), diuretic toxins, bradykinin potentiating peptides (BPPs), antimicrobial peptides (AMP), enzymes, and other toxins (Verano-Braga et al., 2013 ).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website.
Lethal dose
Taxonomy

UniProt taxonomy
Wikipedia

Order: Scorpiones


Family: Buthidae
Genus: Tityus
Species:serrulatus
Activity Antimicrobial
Hypotensive agent
Neurotoxin
Vasodilator
and also
G-protein coupled receptor impairing toxin
Ion channel impairing toxin
or see
UniProtKB browsing by keyword
Reference Cologna et al., 2009
Verano-Braga et al., 2013

Venom protein entries in UniProtKB/Swiss-Prot

37 entries grouped by species (browse by taxonomy, browse by keywords)

37 entries

Tityus serrulatus (Brazilian scorpion)

Select_allDeselect_all
AMY_TITSE Alpha-amylase (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) ... Glycosyl hydrolase 13 family
CLCPP_TITSE Intracellular calcium channel modulator CCP-Ts (Cell penetrating ... Scorpion calcin-like family
HYAL1_TITSE Hyaluronidase 1 (TsHyal-1) (EC 3.2.1.35) ... Glycosyl hydrolase 56 family
HYAL2_TITSE Hyaluronidase 2 (TsHyal-2) (EC 3.2.1.35) ... Glycosyl hydrolase 56 family
HYTL_TITSE Hypotensin-like peptide (Fragment) Not in a family
KA121_TITSE Potassium channel toxin alpha-KTx 12.1 (Butantoxin) (BuTX) (Ts6) ... Short scorpion toxin ...

pdb 1C55; 1C56; 1WT7

KA20_TITSE Toxin Ts16 (Tityustoxin-16) Short scorpion toxin ...

pdb 2LO7

KA211_TITSE Potassium channel toxin alpha-KTx 21.1 (Tityustoxin-15) (Ts15) Short scorpion toxin ...
KAX41_TITSE Potassium channel toxin alpha-KTx 4.1 (TSK4) (Tityustoxin ... Short scorpion toxin ...

pdb 1HP2

KAX42_TITSE Potassium channel toxin alpha-KTx 4.2 (Neurotoxin Ts-kappa) ... Short scorpion toxin ...

pdb 1TSK; 6ATL

KBX1_TITSE Potassium channel toxin TsTXK-beta (Potassium channel toxin ... Long chain scorpion toxin ...
KBX2_TITSE Ts19 (Potassium channel toxin beta-Ktx 2) [Cleaved into: Ts19 ... Long chain scorpion toxin ...
KEX11_TITSE Potassium channel toxin epsilon-KTx 1.1 (Ts11) (TsPep1) Short scorpion toxin ...

pdb 2MSF

KEX12_TITSE Potassium channel toxin epsilon-KTx 1.2 (Ts12) (TsPep2) Short scorpion toxin ...
KEX1S_TITSE Peptide TsPep3 (Ts13) Short scorpion toxin ...
NDB11_TITSE Bradykinin-potentiating peptide T (BPP-T) (Non-disulfide-bridged ... Non-disulfide-bridged peptide ...
NDB4N_TITSE Antimicrobial peptide TsAP-2 (Non-disulfide-bridged peptide ... Non-disulfide-bridged peptide ...
NDB4S_TITSE Venom peptide 1 [Cleaved into: Venom peptide 2] Non-disulfide-bridged peptide ...
NDB4T_TITSE Venom peptide 3 [Cleaved into: Venom peptide 4; Venom peptide 5] Non-disulfide-bridged peptide ...
NDB4U_TITSE Venom peptide 6 Non-disulfide-bridged peptide ...
NDB4V_TITSE Venom peptide 7.1 (Venom peptide 7) [Cleaved into: Venom peptide ... Non-disulfide-bridged peptide ...
NDBH1_TITSE Hypotensin-1 (Hypotensin I) (TsHpt-I) [Cleaved into: ... Non-disulfide-bridged peptide ...
NDBH2_TITSE Hypotensin-2 (Hypotensin II) (TsHpt-II) [Cleaved into: ... Non-disulfide-bridged peptide ...
NDBM_TITSE Antimicrobial peptide TsAP-1 (Non-disulfide-bridged peptide ... Non-disulfide-bridged peptide ...
NDBP8_TITSE Venom peptide 8 Non-disulfide-bridged peptide ...
PAPE_TITSE Pape peptide (Fragment) Not in a family
SCX1_TITSE Beta-mammal/insect toxin Ts1 (PT-Mice-Ins-beta NaTx6.1) ... Long (4 C-C) scorpion toxin ...

pdb 1B7D; 1NPI

SCX2_TITSE Alpha-mammal toxin Ts2 (P-Mice-beta* NaTx5.1) (Tityustoxin II) ... Long (4 C-C) scorpion toxin ...
SCX3_TITSE Toxin-5 (Tityustoxin V) (Ts V) (TsV) (Toxin V) [Cleaved into: ... Long (4 C-C) scorpion toxin ...

pdb 5CY0

SCX4_TITSE Toxin Ts4 (Non-toxic protein TsNTxP) (NTxP) (P-Allerg-alpha* ... Long (4 C-C) scorpion toxin ...
SCX5_TITSE Alpha-toxin Ts5 (P-alpha* NaTx3.2) (Tityustoxin V) (Toxin V) (Ts ... Long (4 C-C) scorpion toxin ...
TS20_TITSE Peptide Ts20 (Fragment) Not in a family
TSNP_TITSE Natriuretic peptide TsNP Natriuretic peptide family
VA5_TITSE Venom allergen 5 (Antigen 5) (Cysteine-rich venom protein) ... CRISP family, Venom allergen ...
VMPA1_TITSE Venom metalloproteinase antarease TserMP_A (VMPA) (EC 3.4.24.-) ... Venom metalloproteinase (M12B) ...
VMPA2_TITSE Venom metalloproteinase antarease-like TserMP_B (VMPA) (EC ... Venom metalloproteinase (M12B) ...
VMXP_TITSE Venom metalloproteinase (VMP) (EC 3.4.24.-) (Fragments) Venom metalloproteinase (M12B) ...