Pseudonaja textilis (Eastern brown snake)

Venom composition A proteomic analysis of the venom was done in 2006 (Birrell et al., 2006). This study describes the identification of most of the venom proteins previously known: the prothrombin activator complex, which is composed of factor Va-like (from the multicopper oxidase family) and factor Xa-like (from the peptidase S1 family), serine proteinase inhibitors (from the venom Kunitz-type family), various phospholipases A2 (phospholipase A2 family), and pre- and postsynaptic neurotoxins (from the phospholipase A2 family and the three-finger toxin family, respectively). In addition, glucose-regulated protein 78, a protein not previously reported in venom before this study was identified, which is a member of the heat shock protein 70 (HSP70) family. This protein is supposed to play a role in facilitating the assembly of multimeric protein complexes known to exist in the venom (Birrell et al., 2006).

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Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website
and the WHO venomous snake database to access snake distribution and antivenom products.

Venom protein entries in UniProtKB/Swiss-Prot

37 entries grouped by species (browse by taxonomy, browse by keywords)

30 entries

Pseudonaja textilis (Eastern brown snake)

Select_allDeselect_all
3L21_PSETE Long neurotoxin 1 (LNTX-1) Snake three-finger toxin family, ...
3L2B_PSETE Pseudonajatoxin b (Long neurotoxin B) Snake three-finger toxin family, ...
3L2P_PSETE Pseudonajatoxin b homolog (Pt-bp) Snake three-finger toxin family, ...
3S31_PSETE Short neurotoxin 1/5 (SNTX1) (SNTX5) (Alpha-neurotoxin 1/5) Snake three-finger toxin family, ...
3S32_PSETE Short neurotoxin 2 (SNTX2) (Alpha-neurotoxin 2) Snake three-finger toxin family, ...
3S331_PSETE Short neurotoxin N1 (Alpha-neurotoxin) (Fragment) Snake three-finger toxin family, ...
3S332_PSETE Short neurotoxin N2 (Alpha-neurotoxin) (Fragment) Snake three-finger toxin family, ...
3S33_PSETE Short neurotoxin 3 (SNTX3) (Alpha-neurotoxin 3) Snake three-finger toxin family, ...
3S34_PSETE Short neurotoxin 4 (SNTX4) (Alpha-neurotoxin 4) Snake three-finger toxin family, ...
3S36_PSETE Short neurotoxin 6 (SNTX6) (Alpha-neurotoxin 6) Snake three-finger toxin family, ...
3S37_PSETE Short neurotoxin 7 (SNTX7) (Alpha-neurotoxin 7) Snake three-finger toxin family, ...
3S38_PSETE Short neurotoxin 8 (SNTX8) Snake three-finger toxin family, ...
CALGL_PSETE Calglandulin Calmodulin family, Calglandulin ...
CAMP1_PSETE Cathelicidin-related peptide Pt_CRAMP1 (Cathelicidin-related ... Cathelicidin family
CAMP2_PSETE Cathelicidin-related peptide Pt_CRAMP2 (Cathelicidin-related ... Cathelicidin family
CRVP_PSETE Cysteine-rich venom protein pseudechetoxin-like (CRVP) CRISP family
CYT_PSETE Cystatin Cystatin family
FA102_PSETE Coagulation factor X isoform 2 (PFX2) (EC 3.4.21.6) [Cleaved ... Peptidase S1 family, Snake venom ...
FA5V_PSETE Venom prothrombin activator pseutarin-C non-catalytic subunit ... Multicopper oxidase family
FAXC_PSETE Venom prothrombin activator pseutarin-C catalytic subunit (PCCS) ... Peptidase S1 family, Snake venom ...
NGFV1_PSETE Venom nerve growth factor 1 (v-NGF-1) (vNGF-1) NGF-beta family
NGFV2_PSETE Venom nerve growth factor 2 (v-NGF-2) (vNGF-2) NGF-beta family
PA2A1_PSETE Acidic phospholipase A2 1 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...
PA2A2_PSETE Acidic phospholipase A2 2 (svPLA2) (EC 3.1.1.4) ... Phospholipase A2 family, Group I ...
PA2BA_PSETE Basic phospholipase A2 textilotoxin A chain (svPLA2) (EC ... Phospholipase A2 family, Group I ...
PA2HB_PSETE Basic phospholipase A2 homolog textilotoxin B chain (svPLA2 ... Phospholipase A2 family, Group I ...
PA2HC_PSETE Acidic phospholipase A2 homolog textilotoxin C chain (svPLA2 ... Phospholipase A2 family, Group I ...
PA2HD_PSETE Acidic phospholipase A2 homolog textilotoxin D chain (svPLA2 ... Phospholipase A2 family, Group I ...
VNPA_PSETE Natriuretic peptide PtNP-a (Fragment) Natriuretic peptide family
WAPA_PSETE Textwaprin-a Snake waprin family

7 entries

Pseudonaja textilis textilis (Eastern brown snake)

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VKT1_PSETT Kunitz-type serine protease inhibitor textilinin-1 (Txln-1) Venom Kunitz-type family
VKT2_PSETT Kunitz-type serine protease inhibitor textilinin-2 (Txln-2) Venom Kunitz-type family
VKT3_PSETT Kunitz-type serine protease inhibitor textilinin-3 (Txln-3) Venom Kunitz-type family
VKT4_PSETT Kunitz-type serine protease inhibitor textilinin-4 (Txln-4) Venom Kunitz-type family
VKT5_PSETT Kunitz-type serine protease inhibitor textilinin-5 (Txln-5) Venom Kunitz-type family
VKT6_PSETT Kunitz-type serine protease inhibitor textilinin-6 (Txln-6) Venom Kunitz-type family
VKT7_PSETT Kunitz-type serine protease inhibitor textilinin-7 (Txln-7) Venom Kunitz-type family