Agkistrodon piscivorus piscivorus (Eastern cottonmouth)

Venom composition
Figure 1: Composition of A.p.piscivorus venom, studied at proteomic level (Lomonte, et al., 2014 ). This venom contains the following families: SVMP (venom metalloproteinase ), serine protease (peptidase S1 ), peptides (include tripeptide SVMP inhibitors and bradykinin-potentiating and bradykinin-inhibitory peptides), LAAO (L-amino-acid oxidase (flavin monoamine oxidase) ), disintegrin, snaclec (also known as C-type lectin-like), CRISP, PA2 (phospholipase A2 ).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website
and the WHO venomous snake database to access snake distribution and antivenom products.
Lethal dose LD(50) of A.piscivorus is
6.24 mg/kg by intraperitoneal injection and
5.13 mg/kg by intravenous injection (Arce et al., 2003 ).

Venom protein entries in UniProtKB/Swiss-Prot

10 entries grouped by species (browse by taxonomy, browse by keywords)

10 entries

Agkistrodon piscivorus piscivorus (Eastern cottonmouth)

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BPPF_AGKPI Bradykinin-potentiating peptide F (AppF) (BPP-F) Bradykinin-potentiating peptide ...
CRVP_AGKPI Cysteine-rich venom protein piscivorin CRISP family
DIDA_AGKPI Disintegrin piscivostatin-alpha (PVS-alpha) Disintegrin family, Dimeric ...
LECG_AGKPI C-type lectin APL (CTL) True venom lectin family
PA2B1_AGKPI Basic phospholipase A2 APP-D49 (svPLA2) (EC 3.1.1.4) (App-dimer) ... Phospholipase A2 family, Group ...
PA2HB_AGKPI Basic phospholipase A2 homolog (svPLA2 homolog) (APP-K49) ... Phospholipase A2 family, Group ...
TXVE_AGKPI Snake venom vascular endothelial growth factor toxin apiscin ... PDGF/VEGF growth factor family, ...
VEGFA_AGKPI Vascular endothelial growth factor A PDGF/VEGF growth factor family
VM2PB_AGKPI Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2_AGKPI Disintegrin applaggin (Applagin) (Platelet aggregation ... Venom metalloproteinase (M12B) ...