Agkistrodon piscivorus piscivorus (Eastern cottonmouth) (taxid:8716)

Venom composition image
Figure 1: Composition of A.p.piscivorus venom, studied at proteomic level (Lomonte, et al., 2014). This venom contains the following families: SVMP (venom metalloproteinase), serine protease (peptidase S1), peptides (include tripeptide SVMP inhibitors and bradykinin-potentiating and bradykinin-inhibitory peptides), LAAO (L-amino-acid oxidase (flavin monoamine oxidase) ), disintegrin, snaclec (also known as C-type lectin-like), CRISP, PA2 (phospholipase A2).
Clinical Effects, Treatment, Antivenoms See the Clinical Toxinology Resources Website.
Lethal dose LD(50) of A.piscivorus is
6.24 mg/kg by intraperitoneal injection and
5.13 mg/kg by intravenous injection (Arce et al., 2003).

Venom protein entries in UniProtKB/Swiss-Prot

(all links/actions below point to uniprot.org website)

10 entries grouped by species

10 entries

Agkistrodon piscivorus piscivorus (Eastern cottonmouth)

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BPPF_AGKPI Bradykinin-potentiating peptide F (AppF) (BPP-F) Bradykinin-potentiating peptide ...
CRVP_AGKPI Cysteine-rich venom protein piscivorin CRISP family
DIDA_AGKPI Disintegrin piscivostatin-alpha (PVS-alpha) Disintegrin family, Dimeric ...
LECG_AGKPI C-type lectin APL (CTL) True venom lectin family
PA2B1_AGKPI Basic phospholipase A2 APP-D49 (svPLA2) (EC 3.1.1.4) (App-dimer) ... Phospholipase A2 family, Group ...
PA2HB_AGKPI Basic phospholipase A2 homolog AppP2 (svPLA2 homolog) (APP-K49) Phospholipase A2 family, Group ...
TXVE_AGKPI Snake venom vascular endothelial growth factor toxin apiscin ... PDGF/VEGF growth factor family, ...
VEGFA_AGKPI Vascular endothelial growth factor A (VEGF-A) PDGF/VEGF growth factor family
VM2PB_AGKPI Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom ... Venom metalloproteinase (M12B) ...
VM2_AGKPI Disintegrin applaggin (Applagin) (Platelet aggregation ... Venom metalloproteinase (M12B) ...