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Bitis gabonica
(Gaboon viper)
(taxid:8694)
Venom composition
Figure 1: Composition of B.gabonica venom, studied at the proteomic level (
Calvete et al., 2007
). This venom contains the following families:
CRISP
, PLA2 (
phospholipase A2
), LAAO (
L-amino-acid oxidase
), C-type lectin (
true venom lectin
and
Snaclec
), SVMP (snake
venom metalloproteinase
),
serine protease
, BPP (
bradykinin potentiating peptide
), DC-fragment (disintegrin/cysteine-rich fragment from P-III SVMPs),
disintegrin
,
venom Kunitz-type
,
cystatin
,
PDGF/VEGF growth factor
.
Clinical Effects, Treatment, Antivenoms
See the
Clinical Toxinology Resources Website
.
Miscellaneous
B. gabonica produces the largest amounts of venom of all poisonous snakes; yields in excess of 2 grams of dried venom per milking have been recorded.
There are comparatively few recorded cases of human snakebites, due in part to its nocturnal habits and its daytime concealment (
Marsh et al., 1997
).
Taxonomy
UniProt taxonomy
The Reptile database
Wikipedia
Infraorder
:
Serpentes
Family
:
Viperidae
Genus:
Bitis
Species
:
gabonica
Activity
Hemostasis impairing toxin
Blood coagulation cascade activating toxin
or see
UniProtKB browsing by keyword
Reference
Francischetti et al., 2004
Calvete et al., 2007
Venom protein entries in UniProtKB/Swiss-Prot
(all links/actions below point to
uniprot.org
website)
15 entries
grouped
by species
reorder by family
15 entries
Bitis gabonica (Gaboon adder) (Gaboon viper)
CYT_BITGA
Bitiscystatin (Cystatin)
Cystatin family
DID1_BITGA
Disintegrin gabonin-1 (Bitisgabonin-1)
Disintegrin family, Dimeric
...
DID2_BITGA
Disintegrin gabonin-2 (Bitisgabonin-2)
Disintegrin family, Dimeric
...
LEC1_BITGA
C-type lectin 1 (CTL)
True venom lectin family
OXLA_BITGA
L-amino-acid oxidase (LAAO) (LAO) (EC 1.4.3.2)
Flavin monoamine oxidase family,
...
PA2A_BITGA
Acidic phospholipase A2 (svPLA2) (EC 3.1.1.4)
...
Phospholipase A2 family, Group
...
SL2_BITGA
Snaclec 2 (C-type lectin 2)
Snaclec family
SL3_BITGA
Snaclec 3 (C-type lectin 3)
Snaclec family
VEGFA_BITGA
Vascular endothelial growth factor A (VEGF-A) (Vascular
...
PDGF/VEGF growth factor family
VKT1_BITGA
Kunitz-type serine protease inhibitor bitisilin-1 (BG-11)
...
Venom Kunitz-type family
VKT2_BITGA
Kunitz-type serine protease inhibitor bitisilin-2 (BG-15)
...
Venom Kunitz-type family
VKT3_BITGA
Kunitz-type serine protease inhibitor bitisilin-3 (Two-Kunitz
...
Venom Kunitz-type family
VM2BI_BITGA
Zinc metalloproteinase/disintegrin [Cleaved into: Snake venom
...
Venom metalloproteinase (M12B)
...
VSPG_BITGA
Thrombin-like enzyme gabonase (SVTLE) (EC 3.4.21.55)
...
Peptidase S1 family, Snake venom
...
VSPH1_BITGA
Snake venom serine protease homolog 1 (Venom serine
...
Peptidase S1 family, Snake venom
...